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Dom DeLuise

Lactate inflection point (LIP), is the exercise intensity at which the blood concentration of lactate and/or lactic acid begins to increase exponentially. It is often expressed as 85% of maximum heart rate or 75% of maximum oxygen intake. When exercising at or below the lactate threshold, any lactate produced by the muscles is removed by the body without it building up.

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Dominick DeLuise (August 1, 1933 – May 4, 2009) was an American actor, voice actor, comedian, director, producer, chef and author. He was the husband of actress Carol Arthur and the father of actor, director, pianist, and writer Peter DeLuise, and actors David DeLuise and Michael DeLuise. He starred in a number of movies directed by Mel Brooks, in a series of films with career-long best friend Burt Reynolds, and as a voice actor in various animated films by Don Bluth.

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Sia Kate Isobelle Furler

Actor, voice actor, comedian, director, producer, author

Lactate inflection point (LIP), is the exercise intensity at which the blood concentration of lactate and/or lactic acid begins to increase exponentially. It is often expressed as 85% of maximum heart rate or 75% of maximum oxygen intake. When exercising at or below the lactate threshold, any lactate produced by the muscles is removed by the body without it building up. The onset of blood lactate accumulation (OBLA) is often confused with the lactate threshold. With a higher exercise intensity the lactate production exceeds at a rate which it cannot be broken down, the blood lactate concentration will show an increase equal to 4.0mM; it then accumulates at the muscle and then moves to the bloodstream. Regular endurance exercise leads to adaptations in skeletal muscle which prevent lactate levels from rising. This is mediated via activation of PGC-1α which alters the isoenzyme composition of the LDH complex and decreases the activity of the lactate generating enzyme LDHA, while increasing the activity of the lactate metabolizing enzyme LDHB.
Lactate threshold

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Sia