Ohio State Route 341

State Route 703 (SR 703) is a state highway in western Ohio. Its western terminus is in Montezuma at SR 219, and its eastern terminus is in St. Mary's at an intersection with SR 29, SR 66, and the southern terminus of SR 116 in St. Mary's. The route is mainly an east–west highway along the shores of Grand Lake St. Marys, although the section between Celina and Montezuma travels in a more north-south fashion. In 1937, the route was designated from SR 219 to US 127, and it was fully paved by 1940. SR 703 was extended to the northern side of the Grand Lake in 1973, replacing an old alignment of SR 29.

State Route 674 (SR 674) is a state highway located southeast of Columbus, Ohio. Most of the route straddles a county line; about 11 miles (18 km) of the southern part of route is on the Pickaway–Fairfield County line while the next 1.4 miles (2.3 km) is on the Fairfield-Franklin County line. The route's southern terminus is at US 22 just north of Stoutsville while the northern terminus is at an interchange with US 33 in the city of Canal Winchester.

Ohio State Route 23

Ohio State Route 334

Ohio State Route 592

Ohio State Route 523 (OH 523) is a state highway in North Central Ohio. A short connector route, OH 523 links OH 19 at its western terminus with OH 53 at its eastern terminus. OH 523's intersection with OH 53 is located less than 4 miles (6.4 km) northeast of the OH 53 exit off of I-80/I-90/Ohio Turnpike.

In Ohio, State Route 42 may refer to:
* U.S. Route 42 in Ohio, the only Ohio highway numbered 42 since 1927
* Ohio State Route 42 (1923-1927), now SR 95 (Marion to Fredericktown), US 36 (Mount Vernon to Coshocton), and SR 541 (Coshocton to near Kimbolton)

State Route 435 (SR 435, OH 435) is a 4.084-mile (6.573 km) long east–west state highway in the southwestern portion of the U.S. state of Ohio. The western terminus of SR 435 is at a partial interchange with U.S. Route 35 (US 35) approximately 5.50 miles (8.85 km) southwest of Jeffersonville, and its eastern terminus is a T-intersection with SR 729 nearly 2 miles (3.2 km) northeast of Milledgeville. This route follows a former alignment of US 35, which now bypasses this area along a freeway alignment. SR 435 provides access between current U.S. Route 35 and Interstate 71 (I-71), as no direct interchange exists between the two highways.

Ohio State Route 14T

State Route 603 (SR 603) is a north–south state highway in the northern portion of the U.S. state of Ohio. Its southern terminus is at State Route 95 near Perrysville, and its northern terminus is at State Routes 61 and 98 in Plymouth along the Baseline Road that separates Huron County and Richland County, and subsequently the southern boundary of the Firelands and Connecticut Western Reserve.

State Route 370 (SR 370) is 1.21-mile (1.95 km) long north–south state highway in the western part of the U.S. state of Ohio. The highway runs from its southern terminus at the main entrance to John Bryan State Park nearly two miles (3.2 km) southeast of Yellow Springs to its northern terminus at SR 343 about 0.75 miles (1.21 km) east of Yellow Springs. SR 370 was established in the middle of the 1930s. A spur route, it connects John Bryan State Park to the state highway system. This two-lane highway is located in the northern portion of Greene County.

State Route 100 (SR 100) is a north–south highway in northwestern Ohio. Its southern terminus is at State Route 309 near Iberia, and its northern terminus is at State Route 53 in Tiffin.

State Route 117 (SR 117) is an east–west highway in the western part of the U.S. state of Ohio. Its western terminus is at State Route 118 near Rockford, and its eastern terminus is at U.S. Route 33 near Huntsville. It goes through the towns of Spencerville and Lima, and comes close to Indian Lake. East of Lima, the route takes a southeast to south-southeast heading to its eastern terminus.

State Route 46 is a north–south state highway in the northeastern portion of the U.S. state of Ohio. Its southern terminus is at State Route 170 in East Palestine (this point is also the eastern terminus of State Route 558), and its northern terminus is at State Route 11 several miles south of State Route 531 in Plymouth Township. In its northernmost portion, from south of Ashtabula to Cortland, Route 46 is a 2-lane highway while running parallel within a few miles to limited-access State Route 11 to the east.

Ohio State Route 4 (1923)

Ohio State Route 200 (1938)

Ohio State Route 280 (disambiguation)

State Route 323 (SR 323) is an east–west state highway in southwestern Ohio. State Route 323's western terminus is at State Route 41 in South Solon. Its eastern terminus is at State Route 56 just northwest of Mount Sterling.

Ohio State Route 197

Ohio State Route 607 (1986-2006)

Ohio State Route 550

State Route 369 (SR 369) is a short, two-lane north–south state highway in the western portion of the U.S. state of Ohio. The southern terminus of SR 369 is at an interchange with SR 4 approximately two and a half miles (4.0 km) northeast of Enon. Its northern terminus is at U.S. Route 40 (US 40) nearly one and a half miles (2.4 km) east of Donnelsville. SR 369 was created in the mid-1930s. In addition to serving as a connector between SR 4 and US 40 southwest of Springfield, it provides access to a county park named in honor of George Rogers Clark.

Ohio State Route 720

State Route 115 (SR 115, OH 115) is a 21.71-mile (34.94 km) long north–south state highway in the western portion of the U.S. state of Ohio. The highway has its southern terminus at a T-intersection with SR 65 in the northernmost portion of the city of Lima. The northern terminus of SR 115 is at a T-intersection with SR 15 approximately 3.75 miles (6.04 km) southeast of the village of Continental.

State Route 720 (SR 720) is an east–west state highway in the western portion of the U.S. state of Ohio. The highway runs from its western terminus at SR 65 approximately 3.75 miles (6.04 km) north of Jackson Center to its eastern terminus at US 33 in Russells Point. SR 720 was designated in the late 1930s. The route traverses primarily farmland-dominated terrain in southeastern Auglaize County and northwestern Logan County as it connects SR 65 with the vicinity of the southwestern shore of Indian Lake.

Ohio State Highway 87

State Route 258 (SR 258, OH 258) is a state highway that runs 25.64 miles (41.26 km) in eastern Ohio. It travels from US 36 in Newcomerstown to SR 800 in Rush Township community of Stillwater. Most of the route is in Tuscarawas County but the route briefly enters Guernsey and Harrison Counties.

Ohio State Route 164 (1923)

Ohio State Route 607

Ohio State Route 557

Ohio State Highway 797

Ohio State Route 141

Ohio State Route 139

Ohio State Route 311

State Route 167 (SR 167) is a 14.08-mile-long (22.66 km) east–west state highway in the northeastern portion of the U.S. state of Ohio. Its western terminus is at the northern end of the SR 46 and SR 307 concurrency in Jefferson, and its eastern terminus is at the Pennsylvania state line about 13 miles (21 km) south of Conneaut, where Pennsylvania Route 198 (PA 198) continues east. The route was designated in 1923, and has been rerouted three times since.

State Route 500 (SR 500) is a 13.32-mile-long (21.44 km) Ohio State Route that runs between the Indiana state line and Paulding in the US state of Ohio. None of the highway is listed on the National Highway System. Most of the route is a rural two-lane highway and passes through both farmland and residential properties. For much of its path, SR 500 runs generally parallel to the north of Flatrock Creek. The highway was first signed in 1937 on much of the same alignment as today. SR 500 replaced the SR 194 designation of the highway which dated back to 1923; SR 194 ran between Payne and Paulding. Some of the highway was paved in 1937, with the rest of the route being paved in 1951.

In Ohio, State Route 70 may refer to:
* Interstate 70 in Ohio, the only Ohio highway numbered 70 since about 1962
* Ohio State Route 70 (1923), now SR 753 (near Sinking Spring to Greenfield) and SR 41 (Greenfield to Covington)

In Ohio, State Route 40 may refer to:
* U.S. Route 40 in Ohio, the only Ohio highway numbered 40 since 1927
* Ohio State Route 40 (1923-1927), now US 22 (Washington Court House to Zanesville)

State Route 109 (SR 109) is a 52.9-mile (85.1 km) state route that runs between Ottawa and the Michigan state line in the US state of Ohio. It crosses a major river, the Maumee, east of Napoleon. Most of the route is a rural two-lane highway and passes through both farmland and residential properties. The highway was first signed in 1930 on much the same alignment as today. SR 109 replaced the SR 65 designation, between SR 110 and the Michigan state line, that dates back to 1923. Some of the highway was paved in 1930, with the rest of the route being paved in 1939.

Ohio State Route 26 (1923)

State Route 67 (SR 67) is an east–west state highway in the U.S. state of Ohio. Its western terminus is at an interchange with U.S. Route 33 (US 33) just south of Wapakoneta, which is also the southern terminus for both SR 198 and SR 501, and its eastern terminus is at SR 18 and SR 19 in Republic.

State Route 197 (SR 197) is 25.28-mile (40.68 km) east–west state highway in the western part of the U.S. state of Ohio. The western terminus of SR 197 is at a signalized intersection in downtown Celina that marks the junction of U.S. Route 127 (US 127), SR 29 and SR 703. SR 197 has its eastern terminus at SR 198 nearly 2 miles (3.2 km) southeast of the village of Buckland.

State Route 612 (SR 612) was a state route located in Cuyahoga County, Ohio. The route existed from 1937 until 1951.

State Route 557 (SR 557, OH 557) is a two-lane north–south state highway in the central portion of Ohio, a U.S. state. The highway's southern terminus is at a T-intersection with State Route 643 approximately 2 miles (3.2 km) north of Baltic. Its northern terminus is at a T-intersection with the concurrency of U.S. Route 62 and State Route 39 nearly 1.5 miles (2.4 km) west of the unincorporated community of Berlin.

Ohio State Route 223 (1927-1930)

Ohio State Route 619

State Route 630 (SR 630) is a 2.56-mile-long (4.12 km) east–west state highway in the northeastern quadrant of the U.S. state of Ohio. The western terminus of SR 630 is at a signalized intersection with SR 170 in the northern end of the village of New Middletown. Its eastern terminus is at the Pennsylvania state line nearly two miles (3.2 km) east of New Middletown. Upon crossing the border, SR 630 becomes Pennsylvania Route 317 (PA 317), which continues east to Bessemer.

State Route 253 (SR 253) is a very short east–west state highway in the southern part of the U.S. state of Ohio. With an overall length of just 0.56 miles (0.90 km), the majority of SR 253 is a part of the Jesse Stuart Memorial Bridge, which crosses over the Ohio River near Franklin Furnace, Ohio. The western terminus of SR 253 is at about the midspan of the bridge, where it crosses the Kentucky State Line and becomes Kentucky Route 10 (KY 10). The eastern terminus of the highway is at a diamond interchange with U.S. Route 52 (US 52) near the eastern landing of the Ohio River crossing. The current SR 253 was established in the late 1980s. However, an earlier version of the highway existed in the Medina vicinity from the early 1920s until the late 1950s.

Ohio State Route 153

Ohio State Route 235

In Ohio, State Route 68 may refer to:
* U.S. Route 68 in Ohio, the only Ohio highway numbered 68 since about 1933
* Ohio State Route 68 (1923), now SR 47

State Route 53 is a north–south state highway in the U.S. state of Ohio (physically northeast-southwest). Its southern terminus is at the beginning of the U.S. 68/S.R. 67 concurrency in Kenton, Ohio, and its northern terminus is on Catawba Island in Ottawa County, north of Port Clinton.

Ohio State Route 46

Ohio State Route 167

Ohio State Route 18 (1923)

State Route 141 (SR 141) is an east–west highway crossing through southeast Ohio, though it predominantly runs more north–south. Its western terminus is at U.S. Route 52 in Ironton. The eastern terminus at State Route 7 is in Gallipolis. The route is very scenic as it travels through rural areas of Lawrence and Gallia Counties. The road is hilliest in the westernmost 12 miles (19 km). As you move further east, the road becomes somewhat flatter as it often parallels Symmes Creek. Traveling the road from end to end, one will cross Symmes Creek five times and pass through several communities including Ironton, Hecla, Kitts Hill, Aid, Wilgus, Arabia, Waterloo, Cadmus, Gage, Centenary, and Gallipolis. Symmes Valley High School and Symmes Valley Elementary School are also located along State Route 141, just to the east of Aid. Because of the close proximity to Symmes Creek through the central portion of the route, the roadway is sometimes flooded in rainy periods. This occurs most notably just south of Cadmus. The route in Gallia County is scenic in that there are several Amish settlements.

Ohio State Route 20 (1923)

Monastery Road

Ohio State Route 612

State Route 300 (SR 300, OH 300) is a 6.33-mile (10.19 km) long north–south state highway in northwestern Ohio, a U.S. state. The southern terminus of SR 300 is at a T-intersection with U.S. Route 6 (US 6) approximately 1.50 miles (2.41 km) west of the village of Helena. Its northern terminus is at US 20 just over 2.50 miles (4.02 km) southeast of Woodville.

State Route 582 (SR 582) is an east–west state highway in the northwestern portion of the U.S. state of Ohio. The western terminus of SR 582 is at a T-intersection with SR 65 nearly 2 miles (3.2 km) west of Haskins. Its eastern terminus is also at a T-intersection, this time with SR 105 less than 0.50 miles (0.80 km) southwest of Woodville.

State Route 575 (SR 575) is a 2.60-mile-long (4.18 km) north–south state highway located in the northern portion of the U.S. state of Ohio. The route is located entirely within the western half of Kelleys Island, one of the Lake Erie Islands. The highway runs from its southern terminus at the Neumans Ferry Dock at the south end of the island to its northern terminus at a T-intersection with Division Street in the northern part of the island. This highway, along with SR 357 on South Bass Island, is isolated from the rest of Ohio, and all other Ohio state highways. The route was created in 1937 and has not changed since.

Ohio State Route 181 (1923)

Ohio State Route 53

State Route 444 (SR 444, Ohio 444) is an 8.43-mile (13.57 km) state route that runs from Dayton through Fairborn in the US state of Ohio. Most of the north–south signed route is an urban four-lane highway which passes through both commercial and residential properties. For some of its path, SR 444 passes through Wright-Patterson Air Force Base.

State Route 242 (SR 242) was an east–west state highway in the west-central portion of Ohio. The western terminus of the route was at U.S. Route 127 approximately 5 miles (8.0 km) north of Greenville. Its eastern terminus was at a T-intersection with SR 121 adjacent to Darke County Airport about 1.5 miles (2.4 km) southwest of Versailles.

Ohio Glass Museum

In Ohio, State Route 234 may refer to:
* Ohio State Route 234 (1920s), now part of SR 93
* Ohio State Route 234 (1930s), now part of SR 60 and SR 754

State Route 661 (SR 661) is a 22.22-mile (35.76 km) long north–south state highway in the central portion of the U.S. state of Ohio. The southern terminus of SR 661 is at a diamond interchange with SR 16 and SR 37 just 0.25 miles (0.40 km) south of Granville. SR 661 has its northern terminus at a signalized T-intersection with SR 13 in the southern end of Mount Vernon.

State Route 217 (SR 217) is an east–west state highway in the southern portion of the U.S. state of Ohio. The western terminus of State Route 217 is at a T-intersection with State Route 141 approximately 1.75 miles (2.82 km) east of the unincorporated community of Kitts Hill. Its eastern terminus is at State Route 7 nearly 1.25 miles (2.01 km) north of the village of Athalia. The route mainly passes through some hilly terrain and drops in elevation before reaching the Ohio River valley.

Ohio State Route 729

Ohio State Route 435

Ohio State Route 207

State Route 141 (SR 141) is an east–west highway crossing through southeast Ohio, though it predominantly runs more north–south. Its western terminus is at U.S. Route 52 in Ironton. The eastern terminus at State Route 7 is in Gallipolis. The route is very scenic as it travels through rural areas of Lawrence and Gallia Counties. The road is hilliest in the westernmost 12 miles (19 km). As you move further east, the road becomes somewhat flatter as it often parallels Symmes Creek. Traveling the road from end to end, one will cross Symmes Creek five times and pass through several communities including Ironton, Hecla, Kitts Hill, Aid, Wilgus, Arabia, Waterloo, Cadmus, Gage, Centenary, and Gallipolis. Symmes Valley High School and Symmes Valley Elementary School are also located along State Rou

Ohio State Route 647

Ohio State Route 10 (1923-1927)

State Route 619 (SR 619) is an east–west state highway in the northeastern quadrant of the U.S. state of Ohio. The western terminus of State Route 619 is at an interchange with the Interstate 76/U.S. Route 224 freeway in Barberton. Its eastern terminus is at State Route 183 in Alliance.

Ohio State Route 242

Ohio State Route 161J

Ohio State Route 130

Ohio State Route 228 (1923)

State Route 707 (SR 707) is a 19.45-mile-long (31.30 km) east–west state highway in the western portion of the U.S. state of Ohio. The western terminus of SR 707 is at the Indiana state line approximately 7.50 miles (12.07 km) southwest of Willshire, where it transitions into Indiana State Road 218. The eastern terminus of SR 707 is at SR 117 nearly 3 miles (4.8 km) north of Mendon.

Ohio State Route 224 (disambiguation)

Ohio State Highway 684

Ohio State Route 681

Ohio State Route 125

Ohio State Route 102 (1923)

Ohio State Route 180

State Route 222 (SR 222) is a 29.14-mile-long (46.90 km) north–south state highway in the southwestern part of the U.S. state of Ohio. The southern terminus of SR 222 is at U.S. Route 52 (US 52) in the village of Chilo. Its northern terminus is at a signalized T-intersection with US 50 approximately 3.50 miles (5.63 km) northwest of Batavia.

Ohio State Route 172 (1923)

Ohio State Route 115

Ohio State Route 326 (1930s)

State Route 304 (SR 304) is an east–west state highway in the northeastern portion of Ohio, a U.S. state. The western terminus of SR 304 is at a signalized intersection with US 422 in Girard. Its eastern terminus is at the Pennsylvania State Line nearly 3 miles (4.8 km) east of Hubbard, where the highway continues east as Pennsylvania Route 318. Created in the early 1930s, SR 304 traverses the northern suburban portions of the Youngstown area. The state highway generally runs in parallel with Interstate 80 for its entire length.

State Route 681 (SR 681) is a 39.53-mile (63.62 km) long east–west state highway in the southern portion of the U.S. state of Ohio. The western terminus of SR 681 is at a T-intersection with SR 356 approximately 6.75 miles (10.86 km) northwest of Albany. Its eastern terminus is also at a T-intersection, this time with SR 124 nearly 9.50 miles (15.29 km) southeast of Coolville.

State Route 175 (SR 175) is a 15.70-mile (25.27 km) long north–south state highway in the northeastern part of the U.S. state of Ohio. The southern terminus of SR 175 is at a signalized intersection with SR 43 in Solon. Its northern terminus is at a signalized intersection with SR 283 in Euclid.

In Ohio, State Route 23 may refer to:
* U.S. Route 23 in Ohio, the only Ohio highway numbered 23 since 1927
* Ohio State Route 23 (1923-1927), now SR 2 (Port Clinton to Toledo), SR 120 (Toledo to near Sylvania), and US 20 (near Sylvania to Indiana)

Ohio State Route 703

Ohio State Route 33 (1923)

Ohio State Route 2 (1920s)

State Route 153 (SR 153) is a 14.69-mile (23.64 km) long east–west state highway in the northeastern portion of the U.S. state of Ohio. The western terminus of SR 153 is at a signalized intersection with southbound SR 43 in Canton, along a stretch of SR 43 where that highway is divided into a one-way couplet. SR 153 has its eastern endpoint at SR 183 nearly 4 miles (6.4 km) south of Alliance.

Ohio State Route 136

State Route 287 (SR 287) is a 13.69-mile-long (22.03 km) east–west state highway in the western portion of the U.S. state of Ohio. The western terminus of SR 287 is at SR 245 nearly 1.75 miles (2.82 km) east of West Liberty. Its eastern terminus is at an interchange with U.S. Route 33 (US 33) about 5.25 miles (8.45 km) northeast of North Lewisburg that dually serves as the southern terminus of SR 739. This two-lane state route was created in the early 1930s. Until an extension in the late 1990s, SR 287 was entirely within Logan County. The extension into Union County was formerly part of US 33.

State Route 365 (SR 365) is a very short two-lane east–west state highway in western Ohio. Its western terminus is at a T-intersection with the SR 235/SR 366 concurrency one mile (1.6 km) north of the village of Lakeview. After running east and south for less than 980 feet (300 m), the highway arrives at its eastern terminus in Indian Lake State Park, serving a boat launch on the western shore of Indian Lake. This spur route was created in 1934, and runs exclusively in Logan County. At a length of just 0.16 miles (260 m), SR 365 is one of the shortest state highways in Ohio.

State Route 647 (SR 647) is a state highway in eastern Ohio connecting the city of Martins Ferry with the village of Mount Pleasant. 9.96 miles (16.03 km) in length, its southern terminus is at SR 7 and its northern terminus is at SR 150.

Ohio State Route 690J

Ohio State Route 127 (disambiguation)

Ohio State Route 575

Ohio State Route 100

Ohio State Route 193 (SR 193, OH 193) is a north–south state highway in the northeastern portion of the U.S. state of Ohio. Its southern terminus is at an interchange with I-680 in Youngstown, and its northern terminus is at OH 531 in North Kingsville.

Ohio State Route 508

State Route 266 (SR 266) is a 14-mile-long (23 km) east–west state highway located in the southeastern portion of Ohio. SR 266's western terminus is at an intersection with SR 377 nearly 3 1⁄2 miles (5.6 km) northwest of Stockport, and its eastern terminus is an intersection with SR 60 approximately 4 1⁄2 miles (7.2 km) northwest of Beverly.

State Route 238 (SR 238) was a short northwest–southeast state highway in the southwestern portion of Ohio. At just over 1 mile (1.6 km) in length, State Route 238 had its southern terminus at the U.S. Route 62 (US 62)/SR 3 concurrency less than 1 mile (1.6 km) southeast of Bloomingburg. Its northern terminus was at SR 38 in the downtown of the Fayette County village.

State Route 180 (SR 180) is a 29.55-mile (47.56 km) long east–west state highway in the southern portion of the U.S. state of Ohio. SR 180 has its western terminus at a T-intersection with SR 159 nearly 5 miles (8.0 km) northeast of Chillicothe. Its eastern terminus is at a diamond interchange with the U.S. Route 33 (US 33) expressway approximately 3.75 miles (6.04 km) northwest of Logan.

State Route 293 (SR 293) is a 6.277-mile-long (10.102 km) north–south state highway in the northwestern portion of the U.S. state of Ohio. The southern terminus of SR 293 is at SR 53 nearly one-half mile (0.80 km) south of the village limits of Kirby. Its northern terminus is at the intersection of Sandusky Street and Cass Street in Wharton. The route was designated in 1932, and was extended south in 1997.

Ohio State Route 49 (1923-1927)

Ohio State Route 214

State Route 444 (SR 444, Ohio 444) is an 8.43-mile (13.57 km) state route that runs from Dayton through Fairborn in the US state of Ohio. Most of the north–south signed route is an urban four-lane highway which passes through both commercial and residential properties. For some of its path, SR 444 passes through Wright-Patterson Air Force Base. The highway was first signed in 1959 on much the same alignment as today. SR 444 replaced the SR 4 designation of the highway, which dated back to 1927. In 1927, SR 4 replaced SR 52, which was established in 1923. The northern terminus was moved to its current location when a section of Interstate 675 (I–675) opened in 1976. In 2012 a section of the road was rerouted away from the base, using city streets in Fairborn.

Ohio State Issue 1 (2004)

State Route 557 (SR 557, OH 557) is a two-lane north–south state highway in the central portion of Ohio, a U.S. state. The highway's southern terminus is at a T-intersection with State Route 643 approximately 2 miles (3.2 km) north of Baltic. Its northern terminus is at a T-intersection with the concurrency of U.S. Route 62 and State Route 39 nearly 1.5 miles (2.4 km) west of the unincorporated community of Berlin. Established in 1937, SR 557 runs exclusively within Holmes County. The highway had a temporary designation from the late 1940s to the early 1960s. The entire road was paved in 1950. The entire route is part of a scenic byway.

Ohio State Route 42

State Route 235 (SR 235) is a 133.2-mile-long (214.4 km) north–south state highway in the western portion of the U.S. state of Ohio. Its southern terminus is at US 68 near the small town of Oldtown just north of Xenia, and its northern terminus is at State Route 65 at the Maumee River nearly 5 miles (8.0 km) east of Grand Rapids. Prior to late 1968, it was numbered State Route 69, but was renumbered 235. There are a number of urban legends pertaining to why this renumbering occurred. One is that the number 69 has certain sexual meanings in popular culture, and the signs kept getting stolen. (There were actually numerous cases of people stealing the signs for this route.) Another was that it was too close to Interstate 69 (less than 70 miles (110 km) in some areas) and the state decided to avoid the confusion.

Ohio State Route 238

State Route 356 (SR 356) is a 10.74-mile-long (17.28 km) state highway in southeastern Ohio. The route connects US 50 in the Knox Township, Vinton County community of Bolins Mills to SR 56 in Waterloo Township, Athens County.

State Route 204 (SR 204) is a state route in central Ohio. It starts at SR 256 in Pickerington, and ends at US 22 near Mount Perry. At a length of 37.79 miles (60.82 km), the route is located parallel to Interstate 70 in Fairfield and Perry counties east of Columbus, the state capital.

Ohio State Route 35 (1923)

Ohio State Route 293

Ohio State Route 674

State Route 41 (SR 41) is a north–south state highway in the southern and western portions of the U.S. state of Ohio. Its southern terminus is at U.S. Route 52, US 62 Business, and US 68 Business in Aberdeen. (US 62 Bus. and US 68 Bus. continue south through Maysville, Kentucky crossing the Ohio River at the Simon Kenton Memorial Bridge from this point); and its northern terminus is along SR 48 at US 36 in Covington. Throughout its southern portion the route is quite hilly as it passes predominantly northward through scenic areas with state parks and monuments. Along its northern portion the route heads in a more westerly direction across mainly flat terrain as a major road through the cities of Washington Court House, Springfield, and Troy.

State Route 145 (SR 145, OH 145) is a 46.14-mile (74.26 km) long north–south state highway in the southeastern quadrant of the U.S. state of Ohio. The western terminus of SR 145 is at a T-intersection with SR 821 in Lower Salem. Its eastern terminus is at a T-intersection with SR 148 approximately 5.25 miles (8.45 km) northeast of Beallsville.

Ohio State Route 32

State Route 607 (SR 607) is a north–south highway near McConnelsville, Ohio. The route starts at SR 60 and travels north to its terminus at SR 78, all located inside Morgan County. SR 607 was designated in 2011, after Monastery Road was transferred from township-maintenance to state-maintenance. The road was then repaved and realigned in 2012, and became signed on July 25, 2013. The route opened to the public on the next day.

Ohio State Route 68

State Route 287 (SR 287) is a 13.69-mile-long (22.03 km) east–west state highway in the western portion of the U.S. state of Ohio. The western terminus of SR 287 is at SR 245 nearly 1.75 miles (2.82 km) east of West Liberty. Its eastern terminus is at an interchange with U.S. Route 33 (US 33) about 5.25 miles (8.45 km) northeast of North Lewisburg that dually serves as the southern terminus of SR 739.

Ohio State Route 117

Ohio State Route 541 (1930s-1940s)

State Route 435 (SR 435, OH 435) is a 4.084-mile (6.573 km) long east–west state highway in the southwestern portion of the U.S. state of Ohio. The western terminus of SR 435 is at a partial interchange with U.S. Route 35 (US 35) approximately 5.50 miles (8.85 km) southwest of Jeffersonville, and its eastern terminus is a T-intersection with SR 729 nearly 2 miles (3.2 km) northeast of Milledgeville.

Ohio State Motto

Ohio State Route 129 (1923)

Ohio State Route 274

Perrysburg–Holland Road

Ohio State Route 290 (1930s-1960s)

State Route 32, also known as SR 32 and the James A. Rhodes Appalachian Highway, is a major east–west highway across the southern portion of the U.S. state of Ohio. It is the eighth longest state route in Ohio. It leads from eastern Cincinnati, near the border between the neighborhoods of Linwood, Mount Lookout, and Columbia-Tusculum, to the Parkersburg-Belpre Bridge across the Ohio River in Belpre. Except in Belpre, leading up to the bridge into West Virginia, the entire route outside Cincinnati's beltway (Interstate 275) is a high-speed four-lane divided highway, forming the Ohio portion of Corridor D of the Appalachian Development Highway System. This corridor continues east across the Ohio River over the Blennerhassett Island Bridge.

State Route 276 (SR 276) is a 6.46-mile (10.40 km) long state highway located entirely in Clermont County, Ohio. The route runs from an intersection with West Main Street (SR 133) and 5th Street in Williamsburg to US 50 and SR 132 in Owensville.

Ohio State Route 356

Ohio State Route 175

State Route 110 (SR 110) is a 10.73-mile (17.27 km) state route that runs between Napoleon and north of McClure in the US state of Ohio. Most of the route is a rural two-lane highway and passes through both farmland and commercial properties. For much of its path, SR 110 runs generally parallel to the south of the Maumee River.

State Route 615 (SR 615) is a 6.93-mile-long (11.15 km) north–south state highway in the northeastern portion of the U.S. state of Ohio. SR 615 runs from its southern terminus at a signalized intersection with SR 306 in Kirtland to its northern terminus at a signalized intersection with SR 283 in Mentor-on-the-Lake.

State Route 626 (SR 626) is a north–south state highway in the northeastern portion of the U.S. state of Ohio. The southern terminus of SR 626 is at SR 165 approximately one and a half miles (2.4 km) southeast of the hamlet of North Lima. Its northern terminus is at SR 7 nearly two miles (3.2 km) south of the township of Boardman.

Ohio State Route 638

Ohio State Route 25 (disambiguation)

Ohio State Route 110

Ohio State Route 262

Ohio State Route 229 (mid-1920s)

Ohio State Route 520

Ohio State Route 664J

Ohio State Highway 746

Ohio State Route 626

Ohio State Route 204

Ohio State Highway 618

State Route 545 (SR 545) is a 17.01-mile (27.37 km) long north–south state highway in the northern portion of the U.S. state of Ohio. The southern terminus of SR 545 is at a T-intersection with SR 39 in the city of Mansfield. Its northern terminus is at the U.S. Route 250 (US 250) and SR 60 concurrency in the village of Savannah.

Ohio State Highway 9

Ohio State Route 194 (1923)

Ohio State Route 370

Ohio State Highway 510

Ohio State Route 563

State Route 266 (SR 266) is a 14-mile-long (23 km) east–west state highway located in the southeastern portion of Ohio. SR 266's western terminus is at an intersection with SR 377 nearly 3 1⁄2 miles (5.6 km) northwest of Stockport, and its eastern terminus is an intersection with SR 60 approximately 4 1⁄2 miles (7.2 km) northwest of Beverly. Located in southeastern Morgan County, SR 266 was first designated in the middle of the 1920s along its current routing. The highway serves the village of Stockport. From the SR 376 intersection to its eastern terminus at SR 60, SR 266 generally straddles the northern banks of the Muskingum River.

Ohio State Route 685

Ohio State Route 240 (1940s-1960s)

Ohio State Route 283 (1931)

Ohio State Route 511C

Ohio State Route 120 (1923)

Ohio State Route 56 (1923)

Ohio State Route 234

Ohio State Route 276

Ohio State Route 471

Ohio State Route 250 (1920s)

State Route 630 (SR 630) is a 2.56-mile-long (4.12 km) east–west state highway in the northeastern quadrant of the U.S. state of Ohio. The western terminus of SR 630 is at a signalized intersection with SR 170 in the northern end of the village of New Middletown. Its eastern terminus is at the Pennsylvania state line nearly two miles (3.2 km) east of New Middletown. Upon crossing the border, SR 630 becomes Pennsylvania Route 317 (PA 317), which continues east to Bessemer. SR 630 was created in the late 1930s. The two–lane highway is provides a connection between PA 317 and the Ohio state highway system.

Ohio State Route 707

Ohio State Route 657

State Route 638 (SR 638) is a two-lane north–south state highway in the west central portion of Ohio, a U.S. state. SR 638 has its southern terminus at an intersection with U.S. Route 68 (US 68) just over six miles (9.7 km) north of the city of Bellefontaine. The northern terminus of the route is at SR 273 at the extreme southeastern corner of the village of Belle Center. Created in the late 1930s, SR 638 runs exclusively within Logan County. Serving as a cutoff route between US 68 and SR 273, the highway passes amid a topography that consists mostly of farm fields, although it also passes several small wooded areas.

Old Oxford Road

Richmond Road

State Route 136 (SR 136) is a north–south state highway in the southwestern portion of the U.S. state of Ohio. Its southern terminus is at its interchange with U.S. Route 52 in Manchester and its northern terminus is at its interchange with U.S. Route 62 near Winchester.

State Route 130 (SR 130) is a short east–west state route in southwestern Ohio. The entirety of SR 130 lies within Butler County. SR 130 has its western terminus at a signalized intersection with U.S. Route 27 (US 27) in McGonigle. Its eastern terminus is also at a signalized intersection, this time at SR 177 in the extreme northwestern corner of Hamilton. For its entire length, SR 130 is alternately known as Old Oxford Road.

State Route 520 (SR 520) is an east–west state highway in the central part of Ohio. SR 520's western terminus is at a T-intersection with SR 514 about 4 miles (6.4 km) southwest of Nashville. The highway's eastern terminus is also at a T-intersection, this time with US 62 just 0.5 miles (0.80 km) southwest of the village Killbuck and US 62's junction with SR 60. SR 520 provides access to the village of Glenmont.

State Route 508 (SR 508) is a two-lane east-west state highway in the western portion of Ohio, a U.S. state. The western terminus of State Route 508 is at a signalized intersection with State Route 235 in the village of De Graff. The route's eastern terminus is at a T-intersection with U.S. Route 68 in West Liberty.

Ohio State Route 59T

Ohio State Route 296 (1930s)

State Route 188 (SR 188) is a 39.04-mile-long (62.83 km) east–west state highway located in the central part of the U.S. state of Ohio. SR 188's western terminus is in Circleville at a signalized intersection where it meets the concurrency of U.S. Route 22 (US 22) and SR 56. Its eastern terminus is at a signalized intersection with SR 204 in the central business district of the village of Thornville.

State Route 657 (SR 657) is a state highway in central Ohio, a U.S. state. While signed as a north–south route, State Route 657 actually travels in a northwest–southeast fashion. The southern terminus of the route is at a T-intersection with SR 13 immediately north of the city limits of Newark. Its northern terminus is at a T-intersection with the concurrency of US 36 and SR 3 about 1 mile (1.6 km) northeast of Centerburg.

Ohio State Route 24 (1923-1927)

Ohio State Route 278

Ohio State Route 21 (1923)

Ohio State Route 155 (1923)

Ohio State Route 253

Ohio State Route 500

Ohio State Route 40

Ohio State Route 103 (1923)

Ohio State Route 523

State Route 326 (SR 326) was the final designation for a short state highway near Holland, Ohio. At the time the route was removed from the state highway system in 1934, the road had been a state highway since the system's creation but with different designations throughout its history.

Ohio State Route 50 (disambiguation)

Ohio State Route 518J

Ohio State Lottery

Ohio State Route 699

State Route 500 (SR 500) is a 13.32-mile-long (21.44 km) Ohio State Route that runs between the Indiana state line and Paulding in the US state of Ohio. None of the highway is listed on the National Highway System. Most of the route is a rural two-lane highway and passes through both farmland and residential properties. For much of its path, SR 500 runs generally parallel to the north of Flatrock Creek.

Ohio State Route 300

Ohio State Route 1 (1923–1927)

Ohio State Route 58 (1923)

Ohio State Route 629

State Route 579 (SR 579) is an east–west state highway in northwestern Ohio, a U.S. state. The western terminus of SR 579 is at SR 51 just south of the city limits of Northwood. Its eastern terminus is at a T-intersection with SR 2 approximately four miles (6.4 km) to the east of Williston.

Ohio State Route 670 (disambiguation)

Ohio State Route 365

In Ohio, State Route 33 may refer to:
* U.S. Route 33 in Ohio, the only Ohio highway numbered 33 since about 1938
* Ohio State Route 33 (1923), now SR 108

State Route 125 (SR 125) is an east–west state highway in the southwestern portion of the U.S. state of Ohio. Its western terminus is within the Cincinnati city limits, about 5 miles (8.0 km) east of downtown, at U.S. Route 50 – this is also the western terminus of State Route 32 and the southern terminus of State Route 561. The route’s eastern terminus is at U.S. Route 52 approximately 7 miles (11 km) west of Portsmouth near the village of Friendship. See also National Scenic Byway, , and Shawnee State Forest and Park map

Ohio State Route 567

Ohio State Route 323

State Route 274 (SR 274) is a two-lane east–west state highway located in the western portion of the U.S. state of Ohio. The western terminus of State Route 274 is at a T-intersection with U.S. Route 127 approximately 4 miles (6.4 km) west of Chickasaw. Its eastern terminus is at another T-intersection, this time with State Route 273 about 3.5 miles (5.6 km) northeast of Rushsylvania.

Ohio State Route 41

State Route 729 (SR 729) is a state highway in central Ohio. The 33.58-mile-long (54.04 km) route runs from SR 73 and SR 350 in the community of Snow Hill, northwest of New Vienna to SR 323 north of Jeffersonville.

State Route 685 (SR 685) is a short east–west state highway in southeastern Ohio, a U.S. state. The western terminus of SR 685 is at SR 78 in the village of Buchtel. Its eastern terminus is at SR 13 approximately one mile (1.6 km) southwest of Jacksonville.

In Ohio, State Route 333 may refer to:
* Ohio State Route 333 (1930s), now part of SR 152
* Ohio State Route 333 (1946–1962), Holland Sylvania Road north of US 20

Ohio State Route 266

Ohio State Route 352

Ohio State Route 345

State Route 553 (SR 553) is a north–south state highway in the southern portion of the U.S. state of Ohio. SR 553 has its southern terminus at a T-intersection with SR 7 in Crown City. The route's northern terminus is at SR 218 approximately two miles (3.2 km) northwest of Crown City. Created in the late 1930s, this highway in extreme southern Gallia County acts primarily as a connector roadway between SR 7 and SR 218. SR 553 is a steep, narrow, and somewhat dangerous route with a large incline from the Ohio River valley heading north into Wayne National Forest.

Ohio State Route 70

Ohio State Route 582

Ohio State Route 603

Ohio State Route 287

State Route 300 (SR 300, OH 300) is a 6.33-mile (10.19 km) long north–south state highway in northwestern Ohio, a U.S. state. The southern terminus of SR 300 is at a T-intersection with U.S. Route 6 (US 6) approximately 1.50 miles (2.41 km) west of the village of Helena. Its northern terminus is at US 20 just over 2.50 miles (4.02 km) southeast of Woodville. SR 300 is a two-lane highway that provides access to the village of Gibsonburg from both US 6 and US 20. When first designated in the early 1930s, SR 300 only connected US 20 to Gibsonburg. Later in that decade, it would be extended south to link the village with US 6.

Ohio State Route 553

Ohio State Route 258

State Route 123 (SR 123) is a state highway in southwestern Ohio. The route runs from SR 251 about seven miles (11 km) southeast of Blanchester to Germantown at SR 4, a distance of 43.6 miles (70.2 km). The section of road from Franklin to Lebanon was originally a toll road until it was taken over by Warren County and made free for public use.

Ohio State Highway 82

State Route 159 (SR 159) is a northeast-southwest state highway (signed north–south) in the south-central portion of the U.S. state of Ohio. Its southern terminus is in Chillicothe at the U.S. Route 50 and State Route 104 concurrency; its northern terminus is at U.S. Route 22 approximately 4 miles (6.4 km) southeast Lancaster.

State Route 334 (SR 334, OH 334) is an east–west state highway in the western part of the U.S. state of Ohio. The western terminus of State Route 334 is at an interchange with U.S. Route 68 less than 0.25 miles (0.40 km) north of the city limits of Springfield. Its eastern terminus is at a T-intersection with State Route 4 approximately 2 miles (3.2 km) northeast of Springfield.

State Route 32, also known as SR 32 and the James A. Rhodes Appalachian Highway, is a major east–west highway across the southern portion of the U.S. state of Ohio. It is the eighth longest state route in Ohio. It leads from eastern Cincinnati, near the border between the neighborhoods of Linwood, Mount Lookout, and Columbia-Tusculum, to the Parkersburg-Belpre Bridge across the Ohio River in Belpre.

Ohio State Route 148 (1923)

Ohio State Route 222

State Route 125 (SR 125) is an east–west state highway in the southwestern portion of the U.S. state of Ohio. Its western terminus is within the Cincinnati city limits, about 5 miles (8.0 km) east of downtown, at U.S. Route 50 – this is also the western terminus of State Route 32 and the southern terminus of State Route 561. The route’s eastern terminus is at U.S. Route 52 approximately 7 miles (11 km) west of Portsmouth near the village of Friendship. Heading east from the Cincinnati neighborhoods of Mount Lookout, Linwood, and Mount Washington, State Route 125 passes through numerous subdivisions in Anderson Township as a four lane road, Beechmont Avenue. After Nordyke Road, State Route 125 becomes Ohio Pike, the old Ohio Turnpike, originally built in 1831 by E.G. Penn, not related to the modern highway of the same name. Passing under Interstate 275, State Route 125 begins to lose its suburban feel after the villages of Amelia and Hamlet as it heads into the countryside of eastern Clermont, Brown, Adams, and Scioto Counties. Near its eastern terminus, the route passes through Shawnee State Forest, the largest in the state of Ohio, and by the Shawnee State Lodge and Park, , and . This section of State Route 125 is part of the Scenic Scioto Heritage Trail. See also National Scenic Byway, , and Shawnee State Forest and Park map

Ohio State Route 179

Ohio State Route 188

Ohio State Route 123

State Route 179 (SR 179) is a 15.52-mile (24.98 km) long north–south state highway in the central portion of the U.S. state of Ohio. SR 179 runs from its southern terminus at the duplex of SR 39 and SR 60 nearly 0.50 miles (0.80 km) northwest of the limits of the village of Nashville to its northern terminus at a signalized intersection with SR 60 in Hayesville.

Ohio State Route 33

State Route 242 (SR 242) was an east–west state highway in the west-central portion of Ohio. The western terminus of the route was at U.S. Route 127 approximately 5 miles (8.0 km) north of Greenville. Its eastern terminus was at a T-intersection with SR 121 adjacent to Darke County Airport about 1.5 miles (2.4 km) southwest of Versailles. Created in the middle of the 1920s, SR 242 ran through very flat farm country in the northeastern portion of Darke County. The highway abutted the western and northern edges of Darke County Airport along the way. The entire route was turned over to county and township control around 2013 in conjunction with a plan to extend the runway of the Darke County Airport.

State Route 235 (SR 235) is a 133.2-mile-long (214.4 km) north–south state highway in the western portion of the U.S. state of Ohio. Its southern terminus is at US 68 near the small town of Oldtown just north of Xenia, and its northern terminus is at State Route 65 at the Maumee River nearly 5 miles (8.0 km) east of Grand Rapids.

Ohio State Highway 800

Ohio State Horse Chestnuts

Ohio State Route 109

Ohio State Route 545

Ohio State Route 630

State Route 139 (SR 139) is a north–south road that stretches from New Boston at its southern terminus to Jackson, Ohio at its northern terminus. This route offers a quick, yet narrow and sharp route to Jackson. US 23 and SR 32 offer a more straight route with a higher speed limit, though less direct.

State Route 550 (SR 550) is an east–west state highway in the southeastern portion of the U.S. state of Ohio. The western terminus of SR 550 is at an interchange with U.S. Route 33 (US 33) just north of the city limits of Athens, immediately south of the southern terminus of SR 13. The eastern terminus of SR 550 is at an intersection with SR 7 just west of Marietta.

Ohio State Route 480

Ohio State Route 159

Ohio State Route 185 (1927-1937)

Ohio State Route 245 (1920s-1930s)

State Route 139 (SR 139) is a north–south road that stretches from New Boston at its southern terminus to Jackson, Ohio at its northern terminus. This route offers a quick, yet narrow and sharp route to Jackson. US 23 and SR 32 offer a more straight route with a higher speed limit, though less direct. SR 139 begins at an intersection with US 52 in New Boston. The route goes north through a couple of traffic lights before passing through Portsmouth, Eden Park, Twin Valley, Rubyville, and Clarktown before it continues due east toward Minford. From there it crosses SR 335 and then begins to turn north once again. After reaching the Scioto County and Jackson County line, SR 279 splits off of State Route 139 and heads toward Oak Hill. SR 139 crosses SR 32 just outside Jackson and SR 776 within less than mile of downtown. The route then briefly overlaps SR 93 in downtown Jackson, terminating 0.15 miles (0.24 km) north where State Route 93 turns east.

Ohio State Route 217

State Route 207 (SR 207, OH 207) is a 31.23-mile (50.26 km) long north–south state highway in the southern portion of the U.S. state of Ohio. The southern terminus of SR 207 is at a diamond interchange with U.S. Route 23 (US 23) nearly 4 miles (6.4 km) north of Chillicothe. Its northern terminus is in Mount Sterling, following a 0.33-mile (0.53 km) long concurrence with US 62 and SR 3, at the intersection where they meet SR 56.

State Route 685 (SR 685) is a short east–west state highway in southeastern Ohio, a U.S. state. The western terminus of SR 685 is at SR 78 in the village of Buchtel. Its eastern terminus is at SR 13 approximately one mile (1.6 km) southwest of Jacksonville. Existing in the northern portion of Athens County, SR 685 functions as a connector route between SR 78 and SR 13 as it makes its way through the Wayne National Forest. The designation of SR 685 came into being in the early 1960s, replacing what had been known as SR 675, due to the construction of Interstate 675 in the Dayton vicinity, and the fact that Ohio does not duplicate numbers among different types of highways.

State Route 278 (SR 278) is a north–south state highway located in the southeastern part of the U.S. state of Ohio. The southern terminus of SR 278 is at US 50 approximately 4.75 miles (7.64 km) east of McArthur. The highway's northern terminus is at the T-intersection it has with SR 595 nearly 5.50 miles (8.85 km) northwest of Nelsonville. Established in the early 1930s, SR 278 primarily connects rural communities in Vinton, Hocking, and Athens Counties. In Vinton County, it passes through and provides access to the Zaleski State Forest and Lake Hope State Park.

State Route 238 (SR 238) was a short northwest–southeast state highway in the southwestern portion of Ohio. At just over 1 mile (1.6 km) in length, State Route 238 had its southern terminus at the U.S. Route 62 (US 62)/SR 3 concurrency less than 1 mile (1.6 km) southeast of Bloomingburg. Its northern terminus was at SR 38 in the downtown of the Fayette County village. Designated in the mid-1920s and located in the northeastern quadrant of Fayette County, SR 238 essentially served as a spur route between the US 62/SR 3 concurrency and SR 38, as the two routes ran generally parallel with one another at a separation of about 1 mile (1.6 km) for a distance of approximately 3.5 miles (5.6 km) between Washington Court House and Bloomingburg. This route provided a connection for the parallel state-maintained roadways at the northeastern end of the run in parallel.

Ohio State Route 193

Ohio State Highway 99

Ohio State Route 695

James A. Rhodes Appalachian Highway

Ohio State Highway 781

Ohio State Highway 85

Ohio State Highway 752

State Route 345 (SR 345) is a north–south state highway in the eastern portion of the U.S. state of Ohio. The southern terminus of SR 345 is at a signalized intersection with the SR 13/SR 37 concurrency in New Lexington. Its northern terminus is at a T-intersection with U.S. Route 22 (US 22) in the unincorporated community of East Fultonham.

Ohio State Route 615

State Route 638 (SR 638) is a two-lane north–south state highway in the west central portion of Ohio, a U.S. state. SR 638 has its southern terminus at an intersection with U.S. Route 68 (US 68) just over six miles (9.7 km) north of the city of Bellefontaine. The northern terminus of the route is at SR 273 at the extreme southeastern corner of the village of Belle Center.

Ohio State Route 304

Ohio State Route 67

Ohio State Route 333

Ohio State Route 444

Ohio State Route 369

Ohio State Route 661

Ohio State Route 270 (1928-1962)

Ohio State Route 579

State Route 703 (SR 703) is a state highway in western Ohio. Its western terminus is in Montezuma at SR 219, and its eastern terminus is in St. Mary's at an intersection with SR 29, SR 66, and the southern terminus of SR 116 in St. Mary's. The route is mainly an east–west highway along the shores of Grand Lake St. Marys, although the section between Celina and Montezuma travels in a more north-south fashion.

Ohio State Route 52 (1923)

Ohio State Route 145

Ohio State Route 30 (1923-1927)

State Route 626 (SR 626) is a north–south state highway in the northeastern portion of the U.S. state of Ohio. The southern terminus of SR 626 is at SR 165 approximately one and a half miles (2.4 km) southeast of the hamlet of North Lima. Its northern terminus is at SR 7 nearly two miles (3.2 km) south of the township of Boardman. Established in the late 1930s, State Route 626 is a two-lane highway that primarily serves local traffic in the southeastern Mahoning County municipality of Beaver Township. Along its path, SR 626 is briefly concurrent with SR 164 to cross over the Ohio Turnpike (Interstate 76 or I-76) just west of the partial interchange it has with I-680.

State Route 110 (SR 110) is a 10.73-mile (17.27 km) state route that runs between Napoleon and north of McClure in the US state of Ohio. Most of the route is a rural two-lane highway and passes through both farmland and commercial properties. For much of its path, SR 110 runs generally parallel to the south of the Maumee River. The highway was first signed in 1923 on much the same alignment as today, bur got as far northeast as Perrysburg. SR 110 was moved to the north side of the Maumee River in 1927. In 1931, the eastern terminus of the route was moved to Grand Rapids. The route was moved back to the south side of the river and the route was extended to Bowling Green in 1942. The eastern terminus of SR 110 was moved to the intersection with SR 65 in 1958.