CYP79A2

CYW

CYXQ

CYP2W1 (cytochrome P450, family 2, subfamily W, polypeptide 1) is a protein that in humans is encoded by the CYP2W1 gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP2W1 is an interesting enzyme since it is mainly expressed in tumors and not in normal human tissue.

CYS Airport

CYRL

CYXX

CYPRES

CYP79D1

Cysteine-rich angiogenic inducer 61 (CYR61) or CCN family member 1 (CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. CYR61 is a secreted, extracellular matrix (ECM)-associated signaling protein of the CCN family (CCN intercellular signaling protein). CYR61 is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vessel formation in placenta, and vascular integrity. In adulthood CYR61 plays important roles in inflammation and tissue repair, and is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.

Cytochrome P450 4A11 is a protein that in humans is encoded by the CYP4A11 gene.

CYP7B1 (gene)

CYQV

CYVA

A CYYM filter is a color filter array. It has one cyan, two yellow, and one magenta element. Developed by Kodak, it was used in the Kodak DCS 620x and DCS 720x DSLRs.

CYUY

CYQH

CYYG

CYYU

CYSB

CYRS

CYP (disambiguation)

CYXJ

CYP2C9*3

CYR-101

CYPC

CYWM

CYP2R1 (gene)

CYP5

CYZS

CYTH2 (gene)

CYSP

CYP2A7 (cytochrome P450, family 2, subfamily A, polypeptide 7) is a protein that in humans is encoded by the CYP2A7 gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum; its substrate has not yet been determined. This gene, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Cytochrome P450 2C9 (CYP2C9), a member of the CYP2C enzyme subfamily, ranks amongst the mostimportant drug metabolizing enzymes in humans. Human CYP2C9 has been shown to exhibit genetic polymorphism. In addition to the wild-type protein CYP2C9*1, at least 32 single nucleotide polymorphisms (SNPs) have been reported within the coding region of the CYP2C9 gene producing the variant allozymes. CYP2C9*3 is one of them. CYP2C9*3 reflects an Ile359-Leu (I359L) change in the amino acid sequence, and have reduced catalytic activity compared with the wild type (CYP2C9*1).

CYP4F8 (gene)

CYP4X1 (cytochrome P450, family 4, subfamily X, polypeptide 1) is a protein which in humans is encoded by the CYP4X1 gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain.

CYP2C9*13

CYVO

CYTN

CYP4V2 (gene)

CYP2E1

CYWE

CYPY

Cytochrome P450 3A5 is a protein that in humans is encoded by the CYP3A5 gene.

CYPR

CYYN

Cytokine-like 1 (CYTL1) is a protein that in humans is encoded by the CYTL1 gene.

CYTF

Cytohesin-2 is a protein that in humans is encoded by the CYTH2 gene.

CYP2U1 (gene)

CYR61

CYTH1 (gene)

CYRCLE (CYRCLE.) is a two-man collective made up of, American artists David Leavitt (Davey Detail) and David Torres (Rabi), born in Los Angeles, California in 2010. Their artwork focuses on life, duality, and the human condition combined with the aesthetic consideration of form, typeface, color, and balance which is what creates their "signature" style. Their works can be seen all over the world and are in public and private collections including that of Shepard Fairey, Ari Emanuel, Sean Combs, and the MGM Grand in Las Vegas.

CYQG

CYP4F2 (gene)

CYYF Airport

CYP2J2

CYT (disambiguation)

Cytochrome P450 2C9 (CYP2C9), a member of the CYP2C enzyme subfamily, ranks amongst the most important drug metabolizing enzymes in humans. Human CYP2C9 has been shown to exhibit genetic polymorphism. In addition to the wild-type protein CYP2C9*1, at least 30 single nucleotide polymorphisms (SNPs) have been reported within the coding region of the CYP2C9 gene producing the variant allozymes. CYP2C9*13 is one of them. It involves a T-to-C transversion at nucleotide position 269 causing a mutation at codon 90, which results in a Leu->Pro substitution. Frequency analysis indicated approximately 2% of the Chinese population carry the allele.

CYXP

CYYH

CYP76B6

CYYO

CYP7A1

CYT Christian Youth Theater

CYP4A22

CYP90D1

CYR 101

CYQW

CYUX

CYP2C18 (gene)

CYSC

CYTH1

CYP4X1

CYP3A5 (gene)

CYSQ

CYP71C4 (gene)

CYP2E1 (gene)

CYPQ

CYP4F22 (gene)

CYP27C1 (gene)

CYP2C8

CYQI

CYVB

CYVP

CYP4Z1

CYP4F3 (gene)

CYP74D

CYSW

CYYR1 (gene)

CYZT

CYT387

CYPD

CYVV

CYP8A1

CYP3A4 (gene)

CYP4

CYT006-AngQb was an investigational vaccine against angiotensin II, designed to lower blood pressure. It was somewhat effective in clinical trials, but less so than conventional drugs against hypertension (elevated blood pressure).

CYWN

CYPK

CYP27B1 (gene)

CYP4A22 (cytochrome P450, family 4, subfamily A, polypeptide 22) also known as fatty acid omega-hydroxylase is a protein which in humans is encoded by the CYP4A22 gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33.

CYP80B1

CYXC

CYWK

CYP71C3 (gene)

CYSJ

CYP4A22 (gene)

CYP2DL1

Cytochrome P450, family 3, subfamily A, also known as CYP3A, is a human gene locus. A homologous locus is found in mice. The CYP3A locus includes all the known members of the 3A subfamily of the cytochrome P450 superfamily of genes. These genes encode monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The CYP3A cluster consists of four genes:
* CYP3A4
* CYP3A5,
* CYP3A7, and
* CYP3A43. The region also contains two pseudogenes:
* CYP3A51P and
* CYP3A52P,

CYPX

CYP5A1

CYVC

CYSD

CYYW

CYWY

CYP79B1

CYQM

CYXH

CYP4Z1 (cytochrome P450, family 4, subfamily Z, polypeptide 1) is a protein that in humans is encoded by the CYP4Z1 gene.

CYSK

CYVQ

CYUB

CYSAF

CYTZ

CYTS

CYTL

CYP7B1 oxysterol 7alpha-hydroxylase

CYPL

CYP90C1

Cytochrome P450 2C18 is a protein that in humans is encoded by the CYP2C18 gene.

CYSY

Cytochrome P450 2C19 (abbreviated CYP2C19) is an enzyme. This protein, a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics, including many proton pump inhibitors and antiepileptics. In humans, the CYP2C19 protein is encoded by the CYP2C19 gene. CYP2C19 is a liver enzyme that acts on at least 10% of drugs in current clinical use, most notably the antiplatelet treatment clopidogrel (Plavix) also drugs that treat pain associated with ulcers, such as omeprazole, antiseizure drugs such as mephenytoin, the antimalarial proguanil, and the anxiolytic diazepam.

CYP3A7

CYR

CYRJ

CYP8B1 (cytochrome P450, family 8, subfamily B, polypeptide 1) also known as sterol 12-alpha-hydroxylase is a protein which in humans is encoded by the CYP8B1 gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP8B1 is unique among the cytochrome P450 genes in that it is intronless.

CYYB

Cytochrome P4502C8 (abbreviated CYP2C8), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the body. Cytochrome P4502C8 also possesses epoxygenase activity, i.e. it metabolizes long-chain polyunsaturated fatty acids, e.g. arachidonic acid, eicosapentaenoic acid, docosahexaenoic acid, and Linoleic acid to their biologically active epoxides.

CYPZ

CYP7A1 (gene)

CYP2C12

Leukotriene-B(4) omega-hydroxylase 2 is an enzyme that in humans is encoded by the CYP4F3 gene. CYP4F3 encodes two distinct enzymes, CYP4F3A and CYP4F3B, which originate from the alternative splicing of a single pre-mRNA precursor molecule; selection of either isoform is tissue-specific with CYP3F3A being expressed mostly in leukocytes and CYP4F3B mostly in the liver.

CYP3

CYRQ

CYP39A1 (cytochrome P450, family 39, subfamily A, polypeptide 1) also known as oxysterol 7-α-hydroxylase 2 is a protein that in humans is encoded by the CYP39A1 gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 24-hydroxycholesterol, 25-hydroxycholesterol and 27-hydroxycholesterol.

CYTH

CYP39

CYP2C19

CYP2C19 (gene)

CYWG

CYTÛN

CYS (disambiguation)

CYPT

CYP2D7BP

CYZF

Leukotriene-B(4) omega-hydroxylase 1 is an enzyme that in humans is encoded by the CYP4F2 gene.

Cytohesin-1 formerly known as Pleckstrin homology, Sec7 and coiled/coil domains 1 (PSCD1) is a protein that in humans is encoded by the CYTH1 gene.

CYQT

CYPlA2

CYP74D1

CYSS

CYSLTR2 (gene)

CYPE

CYP4A11 (gene)

CYP8B1 (cytochrome P450, family 8, subfamily B, polypeptide 1) also known as sterol 12-alpha-hydroxylase is a protein which in humans is encoded by the CYP8B1 gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP8B1 is an endoplasmic reticulum membrane protein and catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of the two primary bile acids, cholic acid and chenodeoxycholic acid, both of which are secreted in the bile. In the intestine these bile acids affect the solubility of cholesterol and other lipids, promoting their absorption. CYP8B1 is unique among the cytochrome P450 genes in that it is intronless.

CYP4Z1 (gene)

CYZX

CYQB

CYQU

CYSL

CYP4A11

CYP2U1

CYVR

CYP46

Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene. CYP2D6 is primarily expressed in the liver. It is also highly expressed in areas of the central nervous system, including the substantia nigra. Other drugs may function as inhibitors of CYP2D6 activity or inducers of CYP2D6 enzyme expression that will lead to decreased or increased CYP2D6 activity respectively. If such a drug is taken at the same time as a second drug that is a CYP2D6 substrate, the first drug may affect the elimination rate of the second through what is known as a drug-drug interaction.

CYQN

CYP71Z6

CYPM

CYP79A1

CYP8

CYTH4 (gene)

CYP71BA1

CYYQ

CYX

CYQ

Cytochrome P450, family 3, subfamily A, also known as CYP3A, is a human gene locus. A homologous locus is found in mice. The CYP3A locus includes all the known members of the 3A subfamily of the cytochrome P450 superfamily of genes. These genes encode monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The CYP3A cluster consists of four genes:
* CYP3A4
* CYP3A5,
* CYP3A7, and
* CYP3A43. The region also contains two pseudogenes:
* CYP3A51P and
* CYP3A52P, as well as several extra exons which may or may not be included in transcripts produced from this region. Previously another CYP3A member, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4.

CYYJ

CYP2D6 (gene)

CYSJ (disambiguation)

CYWL

CYP8B1 (gene)

Cytochrome P450 3A4 (abbreviated CYP3A4) (EC 1.14.13.97) is an important enzyme in the body, mainly found in the liver and in the intestine. It oxidizes small foreign organic molecules (xenobiotics), such as toxins or drugs, so that they can be removed from the body. While many drugs are deactivated by CYP3A4, there are also some drugs which are activated by the enzyme. Some substances, such as grapefruit juice and some drugs, interfere with the action of CYP3A4. These substances will therefore either amplify or weaken the action of those drugs that are modified by CYP3A4. CYP3A4 is a member of the cytochrome P450 family of oxidizing enzymes. Several other members of this family are also involved in drug metabolism, but CYP3A4 is the most common and the most versatile one. Like all members of this family, it is a hemoprotein, i.e. a protein containing a heme group with an iron atom. In humans, the CYP3A4 protein is encoded by the CYP3A4 gene. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q22.1.

CYP71AJ4 (gene)

CYP79B2

CYXN

CYVK

CYPRIS (microchip)

CYXEL

CYPRIS (cryptographic RISC microprocessor) was a cryptographic module developed by the Lockheed Martin Advanced Technology Laboratories. The device was designed to implement NSA encryption algorithms and had a similar intent to the and crypto modules. However, the principal references date back to the late 1990s and it does not appear that the CYPRIS ever earned NSA's Type 1 certification, without which it could not be used to protect classified government traffic.

CYP2C11

CYSCC

Cytochrome P450 2C19 (abbreviated CYP2C19) is an enzyme. This protein, a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics, including many proton pump inhibitors and antiepileptics. In humans, the CYP2C19 protein is encoded by the CYP2C19 gene. CYP2C19 is a liver enzyme that acts on at least 10% of drugs in current clinical use, most notably the antiplatelet treatment clopidogrel (Plavix) also drugs that treat pain associated with ulcers, such as omeprazole, antiseizure drugs such as mephenytoin, the antimalarial proguanil, and the anxiolytic diazepam. CYP2C19 has been annotated as (R)-limonene 6-monooxygenase and (S)-limonene 6-monooxygenase in UniProt.

CYP51

CYP2B6 (gene)

CYP2D1

CYTH2

CYP3A

CYQA

CYSLTR1 (gene)

CYZR

CYP74 cytochrome P-450

CYYC

CYRP

CYTL1 (gene)

CYZY

CYSR

CYRC

CYP3A43 (gene)

CYTH3 (gene)

CYP2C18

CYVD

CYZE

CYSE

CYP88D6

CYXU

CYPS

CYRCLE

CYPN

CYP71AV1

CYP76M7

CYP2A (gene)

CYP2B6

CYPU

CYVZ

CYPG

CYSM

CYP2W1 (gene)

CYWP

Cytochrome P450 2J2 (CYP2J2) is a protein that in humans is encoded by the CYP2J2 gene. CYP2J2 is a member of the cytochrome P450 superfamily of enzymes. The enzymes are oxygenases which catalyze many reactions involved in the metabolism of drugs and other xenobiotics) as well as in the synthesis of cholesterol, steroids and other lipids.

CYST

CYSLTR1

CYSF

CYP8B1

CYP2C10

Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene. CYP2D6 is primarily expressed in the liver. It is also highly expressed in areas of the central nervous system, including the substantia nigra. CYP2D6, a member of the cytochrome P450 mixed-function oxidase system, is one of the most important enzymes involved in the metabolism of xenobiotics in the body. In particular, CYP2D6 is responsible for the metabolism and elimination of approximately 25% of clinically used drugs, via the addition or removal of certain functional groups – specifically, hydroxylation, demethylation, and dealkylation. CYP2D6 also activates some prodrugs. This enzyme also metabolizes several endogenous substances, such as hydroxytryptamines, neurosteroids, and both m-tyramine and p-tyramine which CYP2D6 metabolizes into dopamine in the brain and liver. Considerable variation exists in the efficiency and amount of CYP2D6 enzyme produced between individuals. Hence, for drugs that are metabolized by CYP2D6 (that is, are CYP2D6 substrates), certain individuals will eliminate these drugs quickly (ultrarapid metabolizers) while others slowly (poor metabolizers). If a drug is metabolized too quickly, it may decrease the drug's efficacy while if the drug is metabolized too slowly, toxicity may result. So, the dose of the drug may have to be adjusted to take into account of the speed at which it is metabolized by CYP2D6. Other drugs may function as inhibitors of CYP2D6 activity or inducers of CYP2D6 enzyme expression that will lead to decreased or increased CYP2D6 activity respectively. If such a drug is taken at the same time as a second drug that is a CYP2D6 substrate, the first drug may affect the elimination rate of the second through what is known as a drug-drug interaction.

CYP39A1 (gene)

CYTQ

CYQD

Cytochrome P450 3A4 (abbreviated CYP3A4) (EC 1.14.13.97) is an important enzyme in the body, mainly found in the liver and in the intestine. It oxidizes small foreign organic molecules (xenobiotics), such as toxins or drugs, so that they can be removed from the body. While many drugs are deactivated by CYP3A4, there are also some drugs which are activated by the enzyme. Some substances, such as grapefruit juice and some drugs, interfere with the action of CYP3A4. These substances will therefore either amplify or weaken the action of those drugs that are modified by CYP3A4.

CYP2D6 inhibitor

CYP 450

CYVL

CYP2D6 deficiency

CYTL1

CYZV

CYQR

CYP4F3

25-hydroxycholesterol 7-alpha-hydroxylase also known as oxysterol and steroid 7-alpha-hydroxylase is an enzyme that in humans is encoded by the CYP7B1 gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.

CYR101

CYYY

CYP4X1 (gene)

CYP2D6 inhibitors

CYTIP (gene)

CYRI

CYS

CYP79D4

CYP4A22 (cytochrome P450, family 4, subfamily A, polypeptide 22) also known as fatty acid omega-hydroxylase is a protein which in humans is encoded by the CYP4A22 gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33. CYP4A22 was once considered, along with CYP4A11, CYP4F2, and CYP4F3, as active in metabolizing arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE) by an omega oxidation reaction with the predominant 20-HETE-synthesizing enzymes in humans being CYP4F2 followed by CYP4A11; 20-HETE regulates blood flow, vascularization, blood pressure, and kidney tubule absorption of ions in rodents and possibly humans. However, human CYP4A22 is expressed at very low levels in few tissues and may not be a functional enzyme in regard to the metabolism of arachidnoic acid to 20-HETE.

CYRB

CYZ

CYP2J2 (gene)

CYXT

Cytochrome P450 2E1 (abbreviated CYP2E1, EC 1.14.13.n7) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body. This class of enzymes is divided up into a number of subcategories, including CYP1, CYP2, and CYP3, which as a group are largely responsible for the breakdown of foreign compounds in mammals.

CYP79B3

CYP7B1

CYQL

Cytochrome P450 4F8 is a protein that in humans is encoded by the CYP4F8 gene.

CYUH

Cytochrome P450 2S1 is a protein that in humans is encoded by the CYP2S1 gene. The gene is located in chromosome 19q13.2 within a cluster including other CYP2 family members such as CYP2A6, CYP2A13, CYP2B6, and CYP2F1.

CYYD

CYP3A7 is an enzyme belonging to the cytochrome P450 family. It is 503 amino acids in size and shares 87% of its sequence with CYP3A4. It carries out a similar role in fetuses that CYP3A4 serves in adults. The gene location is 7q22.1. The CYP3A group of enzymes are the most abundantly expressed members of the cytochrome P450 family in liver. They are responsible for the metabolism of more than 50% of all clinical pharmaceuticals.

CYQY

CYRV

CYZW

CYP4F2

CYP4F22

CYP2F1 (gene)

CYZG

CYZP

CYQS

CYRILLIC CAPITAL LETTER GHE WITH UPTURN

CYPH

CYTR

CYPRESS CYCLONES

CYSZ

CYP4F11 (gene)

CYPRIS (cryptographic RISC microprocessor) was a cryptographic module developed by the Lockheed Martin Advanced Technology Laboratories. The device was designed to implement NSA encryption algorithms and had a similar intent to the and crypto modules. However, the principal references date back to the late 1990s and it does not appear that the CYPRIS ever earned NSA's Type 1 certification, without which it could not be used to protect classified government traffic. CYPRIS was designed toaddress the cryptographic requirements of military software radiosand wireless systems. Designed under an NSA contract, CYPRIS wasoptimized to implement a variety oflegacy COMSEC and TRANSEC algorithmswhile enabling field upgrades tonew and emerging INFOSEC algorithms.CYPRIS contains a high performance RISCcore, a reconfigurable hardware unit, anda suite of programmable and automatic systemcheck features. Unprogrammed, CYPRIS is an unclassified, non CCI, exportable device; whenprogrammed it assumes the classification of its software.Over 20 core cryptoalgorithms were developed on CYPRIS.

CYRA

CYWH

CYPlAl

CYSG

CYP3A3

CYRO

CYP2C8 (gene)

CYTIP

CYP93E1

CYYM filter

CYQZ

CYYE

CYZ-10

CYTB

CYP4F12 (gene)

CYXZ

CYP2U1 (cytochrome P450, family 2, subfamily U, polypeptide 1) is a protein that in humans is encoded by the CYP2U1 gene

CYP2C9 (gene)

CYP 2C9

CYP 158A2

CYWA

CYP4F22 (cytochrome P450, family 4, subfamily F, polypeptide 22) is a protein that in humans is encoded by the CYP4F22 gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19 and encodes an enzyme thought to play a role in the 12(R)-lipoxygenase pathway. Mutations in this gene are the cause of ichthyosis lamellar type 3.

CYP450

CYSLTR2

CYYR

CYP39A1

CYP7

CYQF

CYP2A7

CYRA (disambiguation)

CYTE

CYP3A4

CYP4F8

CYP2D6

CYPP

CYP71C1 (gene)

CYUT

CYP2A7 (gene)

CYP99A3

CYP4A21

Cytochrome P450 2B6 is an enzyme that in humans is encoded by the CYP2B6 gene. CYP2B6 is a member of the Cytochrome P450 group of enzymes. Along with CYP2A6, it is involved with metabolizing nicotine, along with many other substances.

CYXS

CYXE

CYP71C2 (gene)

CYYL

Cysteine-rich angiogenic inducer 61 (CYR61) or CCN family member 1 (CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. CYR61 is a secreted, extracellular matrix (ECM)-associated signaling protein of the CCN family (CCN intercellular signaling protein). CYR61 is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vessel formation in placenta, and vascular integrity. In adulthood CYR61 plays important roles in inflammation and tissue repair, and is associated with diseases related to chr

CYSA

CYP2D7AP

CYP2D8P2

CYVM

CYXD

CYSV

CYP2S1 (gene)

CYQQ

CYSN

CYP79D2

CYPW

CYU

CYTB (disambiguation)

CYPO

CYP2C

CYSEC

CYP3A (gene)

CYP2S1

CYP51A1

CYXL

CYWO

CYP2U

CYRM

CYRT

CYRILLIC-ISO

CYWJ

CYP2W1

CYXY

CYP2D7P2

CYT93C

CYZU

CYXR

CYP4B1 (gene)

CYYF

CYVT

CYWV

CYVG

CYPIID6

CYP39A1 oxysterol 7alpha-hydroxylase

CYSU

CYYT

CYSH

CYSO

CYP97C1

CYP79D3

CYT006-AngQb

CYYZ

CYQX

CYXK

CYTJ

CYP720B1

Cytochrome P450 2C9 (CYP2C9), a member of the CYP2C enzyme subfamily, ranks amongst the most important drug metabolizing enzymes in humans. Human CYP2C9 has been shown to exhibit genetic polymorphism. In addition to the wild-type protein CYP2C9*1, at least 30 single nucleotide polymorphisms (SNPs) have been reported within the coding region of the CYP2C9 gene producing the variant allozymes. CYP2C9*13 is one of them. It involves a T-to-C transversion at nucleotide position 269 causing a mutation at codon 90, which results in a Leu->Pro substitution. Frequency analysis indicated approximately 2% of the Chinese population carry the allele. CYP2C9*13 was found in Japanese and Korean, too. CYP2C9*13 allele frequencies in East Asian populations is summarized in Table S of this paper. CYP2C9*13 allele was correlated with reduced plasma clearance of drugs that are substrates for CYP2C9.

CYR61 (gene)

Cytochrome P450 2E1 (abbreviated CYP2E1, EC 1.14.13.n7) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body. This class of enzymes is divided up into a number of subcategories, including CYP1, CYP2, and CYP3, which as a group are largely responsible for the breakdown of foreign compounds in mammals. The CYP2 subfamily is responsible for the majority of P450-mediated drug metabolism in humans. While CYP2E1 itself carries out a relatively low number of these reactions (~4% of known P450-mediated drug oxidations), it and related enzymes CYP1A2 and CYP3A4 are responsible for the breakdown of a large number of toxic environmental chemicals and carcinogens that enter the body, in addition to basic metabolic reactions such as fatty acid oxidations.

CYT

CYYM

CYUL

CYP3A5

CYQK