La Beauce

Coupé Cloué

Le Nord-Médoc

artist

Vineuil
Cour-Cheverny is a commune in the Loir-et-Cher department in the Centre-Val de Loire region of France. The commune's land extends across the Loire Valley and across the Sologne region. Its inhabitants are known as Courchois.

Valdahon

Roussillon

A coupling reaction in organic chemistry is a general term for a variety of reactions where two hydrocarbon fragments are coupled with the aid of a metal catalyst. In one important reaction type a main group organometallic compound of the type RM (R = organic fragment, M = main group centre) reacts with an organic halide of the type R'X with formation of a new carbon-carbon bond in the product R-R' Richard F. Heck, Ei-ichi Negishi and Akira Suzuki were awarded the 2010 Nobel Prize in Chemistry for developing palladium catalyzed cross coupling reactions.Broadly speaking, two types of coupling reactions are recognized:heterocouplings couple two different partners, for example the Heck reaction of an Alkene (RC=CH) and an Alkyl halide (R'-X) to give a substituted Alkene (RC=CR').homocouplings couple two identical partners, for example, the Glaser coupling of two Acetylideo (RC≡CH) to form a dialkyne (RC≡C-C≡CR).^ Organic Synthesis using Transition Metals Rod Bates ISBN 978-1-84127-107-1^ New Trends in Cross-Coupling: Theory and Applications Thomas Colacot (Editor) 2014 ISBN 978-1-84973-896-5^ "The Nobel Prize in Chemistry 2010 - Richard F. Heck, Ei-ichi Negishi, Akira Suzuki". NobelPrize.org. 2010-10-06. Retrieved 2010-10-06. ^ Palladium-Catalyzed Cross-Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize Dr. Carin C. C. Johansson Seechurn, Dr. Matthew O. Kitching, Dr. Thomas J. Colacot, Prof. Victor Snieckus Angew. Chem. Int. Ed. 2012, 51, 5062-5085. doi:10.1002/anie.201107017