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23S rRNA (cytidine2498-2'-O)-methyltransferase (EC 2.1.1.186, YgdE, rRNA large subunit methyltransferase M, RlmM) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (cytidine2498-2'-O-)-methyltransferase.

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23S rRNA (cytidine2498-2'-O)-methyltransferase (EC 2.1.1.186, YgdE, rRNA large subunit methyltransferase M, RlmM) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (cytidine2498-2'-O-)-methyltransferase. This enzyme catalyses the following chemical reactionS-adenosyl-L-methionine + cytidine2498 in 23S rRNA ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + 2'-O-methylcytidine2498 in 23S rRNA^ Purta, E.; O'Connor, M.; Bujnicki, J.M.; Douthwaite, S. (2009). "YgdE is the 2′-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA". Mol. Microbiol. 72: 1147–1158. doi:10.1111/j.1365-2958.2009.06709.x. PMID 19400805.