Captain of the ship doctrine
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Louis Henri
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type: Person
birth place: Paris
spouse: Bathilde d'Orléans
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death date: 1830-08-30
active years end year: 1818
type: NaturalPerson
resting place: Basilica of St Denis
predecessor: Louis Joseph, Prince of Condé
birth place: France
type: Agent
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death place: Château de Saint-Leu
parent: Charlotte de Rohan
parent: Louis Joseph, Prince of Condé
type: Royalty
birth date: 1756-04-13
active years start year: 1818
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name: Louis Henri Joseph de Bourbon
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death place: France
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birth place: Hôtel de Condé

2016 Kaikoura earthquake
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Shahe University Park Station
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Aleksandr Shervashidze
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subject: Category:Abkhazia scenic designers
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Gonghuacheng Station
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Imatinib
comment: Imatinib, sold under the brand names Gleevec and Glivec, used in the treatment of multiple cancers, most notably Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML). Due in large part to the development of Gleevec and related drugs having a similar mechanism of action, the five year survival rate for people with chronic myeloid leukemia nearly doubled from 31% in 1993 (before Gleevec's 2001 FDA approval) to 59% for those diagnosed between 2003 and 2009.
tradename: Gleevec, Glivec
wiki page revision ID: 749539151
pdb ligand: STI
atc prefix: L01
align: left
metabolism: Hepatic
drug name: Imatinib
unii: BKJ8M8G5HI
pregnancy us: D
licence us: IMATINIB
alt: Ball-and-stick model of the imatinib molecule
legal us: Rx-only
caption: Crystallographic structure of tyrosine-protein kinase ABL complexed with imatinib .
drugbank: DB00619
legal ca: Rx-only
pregnancy au: D
routes of administration: Oral
wiki page modified: 2016-11-14T21:30:29Z
excretion: Fecal and renal
synonyms: STI-571
wiki page length: 48707
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legal au: S4
medlineplus: a606018
legal uk: POM
kegg: D08066
atc suffix: XE01
abstract: Imatinib, sold under the brand names Gleevec and Glivec, used in the treatment of multiple cancers, most notably Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML). Due in large part to the development of Gleevec and related drugs having a similar mechanism of action, the five year survival rate for people with chronic myeloid leukemia nearly doubled from 31% in 1993 (before Gleevec's 2001 FDA approval) to 59% for those diagnosed between 2003 and 2009. Median survival for imatinib-treated people with gastrointestinal stromal tumors (GIST) is nearly 5 years compared to 9 to 20 months in the pre-imatinib-era.Compared to older drugs imatinib has a relatively benign side effect profile, allowing many patients to live a normal lifestyle. Imatinib is a tyrosine-kinase inhibitor. It kills cancer cells by blocking the action of tyrosine kinases. In order to survive, cells need signaling through proteins (signal cascade) to keep them alive. Some of the proteins in this cascade use a phosphate group as an "on" switch. This phosphate group is added by a tyrosine kinase enzyme. In healthy cells, these tyrosine kinase enzymes are turned on and off as needed. In Ph-positive CML cells, one tyrosine kinase enzyme, BCR-Abl, is stuck on the "on" position, and keeps adding phosphate groups. Imatinib blocks this BCR-Abl enzyme, and stops it from adding phosphate groups. As a result, these cells stop growing, and even die by a process of cell death (apoptosis). Because the BCR-Abl tyrosine kinase enzyme exists only in cancer cells and not in healthy cells, imatinib works as a form of targeted therapy—only cancer cells are killed through the drug's action. In this regard, imatinib was one of the first cancer therapies to show the potential for such targeted action, and is often cited as a paradigm for research in cancer therapeutics.It is on the World Health Organization's List of Essential Medicines, a list of the medications needed to cover the majority of health[cell cut: 2743 characters, first 2000 kept]
image: Imatinib xtal-2007-balls-and-sticks.png
smiles: Cc1cccNCc4cccCN5CCNC
licence eu: Glivec
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stdinchikey: KTUFNOKKBVMGRW-UHFFFAOYSA-N

Civil society
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Captaincies of the Kingdom of Hungary
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bot: InternetArchiveBot
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fix attempted: yes
date: November 2016
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Shahe Station
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Heroes of Might and Magic IV
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For King & Country (band)
wiki page modified: 2016-11-14T21:30:27Z
comment: For King & Country, stylized as for KING & COUNTRY and formerly known as Joel & Luke as well as Austoville, is a Christian pop duo composed of Australian brothers Joel (born 5 June 1984) and Luke Smallbone (born 22 October 1986). The Nashville-based brothers' 2012 debut record Crave, has received praise, and the brothers were declared by Billboard as one of the "New Artists To Watch" for 2012.
wiki page revision ID: 749539144
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abstract: For King & Country, stylized as for KING & COUNTRY and formerly known as Joel & Luke as well as Austoville, is a Christian pop duo composed of Australian brothers Joel (born 5 June 1984) and Luke Smallbone (born 22 October 1986). The Nashville-based brothers' 2012 debut record Crave, has received praise, and the brothers were declared by Billboard as one of the "New Artists To Watch" for 2012. American Songwriter described them as "Australian's answer to Coldplay."SUSIE Magazine raves, "It takes only one listen to the brothers' rich, upbeat, alternative sounds and thoughtful lyrics to understand their sudden popularity."They describe their philosophy as such:"The power of music can impact our mood, emotions, our day. But when you merge the strength of music with the heart, hope and passion of the Gospel... it has the ultimate power not only to change someone's day, but to impact them for eternity. This is why we write music and sing songs - we hope that people will be moved, encouraged and stirred to live a life for Someone greater than themselves."They cite U2, Mutemath, OneRepublic, The Beatles, The Goo Goo Dolls, and Switchfoot, as well as film scores such as those from Braveheart and Gladiator, as their musical influences.

KBH96
contributor ID: 21621838

Disneyland
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Clonaid
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type: Q24229398
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Jamila Rizvi
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Sephia karta
contributor ID: 288846

Demographics of Liverpool
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Synesthesia
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York St John University Rowing Club
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treasurer: Luke Skelton
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social secretaries: Luke Skelton & Seb Harvey
men's captain: Michael O'Dwyer
women's captain: Thomas Crawley
wiki page length: 6306
name: York St John University Rowing Club
blade image: York St John Rowing Club blade.jpg
motto: Feel the rythym, feel the beat, come on YSJ row your feet
president: Brad Simmons
wiki page modified: 2016-11-14T21:30:25Z

ChicaGo Dash
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Road Recycler
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Rongjingdongjie Station
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Arduino
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United States elections, 2022
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wiki page length: 3107
comment: The 2022 United States elections will be held on Tuesday, November 8, 2022 in the middle of the term of the President who is elected in 2020. During this mid-term election year, all 435 seats in the United States House of Representatives and 34 of the 100 seats in the United States Senate will be contested. 38 state and territorial governorships and numerous other state and local elections will also be contested.
abstract: The 2022 United States elections will be held on Tuesday, November 8, 2022 in the middle of the term of the President who is elected in 2020. During this mid-term election year, all 435 seats in the United States House of Representatives and 34 of the 100 seats in the United States Senate will be contested. 38 state and territorial governorships and numerous other state and local elections will also be contested. This will be the first election affected by the redistricting that will follow the 2020 United States Census.

Wilmington Savings Fund Society
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type: Q24229398
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One Mississippi (TV series)
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comment: One Mississippi is an American comedy television series created by comedian Tig Notaro. The pilot episode aired on Amazon Prime on November 5, 2015, and was picked up for a full series after positive feedback from audiences. Diablo Cody and Louis C.K. worked on the series as executive producers. One Mississippi premiered on September 9, 2016. On November 14, 2016 Amazon renewed the show for a second season.
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Wanyuanjie Station
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AnonWikiEditor
contributor ID: 20535840

GreenC bot
contributor ID: 27823944

PDB complex
type: Property

InternetArchiveBot
contributor ID: 27015025

Puerto Rico national basketball team
wiki page extracted: 2016-11-14T21:30:34Z

Yizhuang Culture Park Station
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Chris the speller
contributor ID: 525927

MOA text
type: Property

Beth Ann Bauman
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Ramón Carnicer
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Vangelis Sklavos
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Life Science Park Station
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wiki page length: 1921
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Mcj1
contributor ID: 29654385

The Siberian Curse
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