yes

Proline oxidase

Tyrone Kingwood
Western Illinois

Right

Benea

Lester Lanin Orchestra

Pete

studio

Football

Nyttend

GABA transporter 1

Central Intelligence Agency front organizations

Patriot League Coach of the Year

McDonnell XV-1

Supernova/Karma

Bell P-59

Howard R. Reiter

Lembo, Pete

GA-Class Alaska articles

Nate

Nathan Eugene Brooks

Canadian ice hockey defenceman

Cleveland State Vikings

Lafayette

Gerry Ashton

George Hoban

Little Mermaid (Disney)

Julian Schlossberg

Seddon

conference

Legends of the Demigods

Andy

Jim Rex

Wilbur Wade Card

Free Citizens Party

Low-importance Alaska articles

T–3rd

John Lindsay Barker

Kyosti

rivalry

United States

Wijk bij Duurstede, Netherlands

Hoban, George William; Hoban, George W.

Fadesga

Continental R-975-19

Hank

Whitehead, John C.

JL-Bot

Small

left|64px|link=:Category:Metra stations Healy

American soccer player-coach

Poster to Madame Aema

Glick

Adam, Jeff, Nathan, and Siri

Jane Boleyn

Волшебник

Rene

January 1993

AussieLegend

under £300,000

Jacob Cohen Bakri

Mike Cooley (American football)

Robertgreer

Wargods

149th overall

The Problem of the Wire Cage

Card, Wilbur Wade

American football coach, college athletics administrator

American football player, coach, official

Howard R.

T–2nd

Theatrical release poster

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It may associate with other G-protein-activated potassium channel subunits to form a heterotetrameric pore-forming complex.

Lowellian

English footballer

Mansfield

This gene encodes a membrane protein that mediates apical cell adhesion between trophoblastic cells and luminal epithelial cells of the endometrium and is implicated in the initial attachment during the process of embryo implantation. This gene is related to the MAGED gene family by sequence similarity and chromosome location. Multiple alternatively spliced transcript variants have been found for this gene; however, the full-length nature of some variants has not been defined.

Patterson Oti

Euclidean Steiner tree

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.

Aarktica

Whitehead, John
national

The Corpse in the Waxworks

Ketiltrout

American football coach, athletic director

Southwest Missouri State

Avoided

The Waxworks Murder

Idaho Steelheads (WCHL) players

Frank

Matession

Linden acres

51–30

Leckonby, William

Elon

Khazar2

James

This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene has a nonsynonymous nucleotide polymorphism at its start codon.

SUPT4H1

WilliamJE

Topbanana

Emerson, New Jersey

High-importance Alaska articles

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents.

Matesi, Greece

Southern Conference Coach of the Year

Scotland School

North Alabama

Leona Valley American Viticulture Area (AVA)

Prendergast pictured in Epitome 1946, Lehigh yearbook

Valparaiso

EmausBot

American football player and coach

L/LeckBi20

Atzori, Fernando

Jeff Blyth

Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene.

USH3A

Boxer

T–1st

Cooley, Mike

Spice Girls: Giving You Everything

Rolling Stone

T-3rd

John Whitehead

Ohconfucius

Jimmy Hogarth

MEP1A

center

STAU1

Karmion

Mike Cooley

Southwest Missouri State Bears

VMI

Billcasey905

Patriot League Championship
Kevin
Richmond

American baseball player

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2.

Myopotamus

75–38–2 (college)

Redding Ridge, Connecticut

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase . AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase and beta-hydroxy beta-methylglutaryl-CoA reductase , key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Joeykai

A. Austin Tate

Emilio Surita

Mansfield Football Club

National Security Agency facilities

Fernando Atzori

September 1967

Liechtenstein at the Olympics

olive

SNTB2

England

Madame Aema

The T-55AM2B has turret brow armour, laser rangefinder over the main gun, rubber side skirts, and thicker front hull armour than the T-55A. Panzermuseum Munster

American educator

Valley Industry and Commerce Association

single

American football player an dcoach

Edward Boleyn

Illinois-Chicago Flames

Michael G. Foster School of Business

coach

Dick Kooijman

Koumáni

9–41 (basketball)

"Supernova/Karma"

Bumar-Łabędy ,

This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.

Vilaetis family

Dual oxidase 1

Jrcla2

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID , which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.

Unknown-importance Alaska articles

Koumanis, Greece

CA12

NAD(P)H dehydrogenase, quinone 2

HIST1H2AM

Waacstats

Coen, Andy

Prendergast, L. F.

Pengo

Pyrope

Greenville, Ohio

Butler

USS Heath Hen

T-4th

Tarporley Painter

Basketball

Brian Bailey (Designer)

Lehigh

0-8217-3384-2 (Zebra paperback edition, 1990)

Lynah

Susan Brown

T–4th

Tony1

William Charles Seddon

Yobot

Central Intelligence Agency training facilities

PSCA (gene)

This gene encodes a member of the regulator of G-protein signaling family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known.

The optical lenticular

Dashiell Rae

National Security Agency operations

RussBot

English ship Swiftsure (1573)

Abraham Broidman

Oliver Hazard Perry class frigate infobox templates

American football player and coach, golf coach, college athletics administrator

Australian businessman

TAFII28

Karma/Supernova

Flowerparty

1–2 (NCAA D-I-AA playoffs)

The Enchanter

Frank Glick

Fram

T–5th

CL0012

RFX5

Mackensen

Korean

Interleukin 13 receptor, alpha 1

Black Joy (1977 film)

The Bushranger

Cooley

Leo Prendergast

Tbonnie

Grundle2600

Kevin Higgins (American football)

Western Illinois Leathernecks

TAF11

Night Vision Imaging System

Волшебник (Volshebnik)

Northwest Alabama

Choi Chun-ji

True True Lie

1985–86 Cleveland State Vikings men's basketball team

Kyösti Karjalainen

Ed Mash

The Citadel

MYH11

SPRR3

President of Columbia College

Central Intelligence Agency operations

not known

Black Joy

Margaret Butler

HMS Speedwell (1607)

Nate Brooks

Chubbles

Missouri State University

Dave

McDonnell Aircraft

Illia Connell

Valparaiso Crusaders

This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA decay candidates, hence not represented as reference sequences.

Brooks, Nate

Sue

N/A

Bakri, Jacob

Nathan Brooks

"Karma"

Martocticvs

QuartierLatin1968

Gordon

Connormah

A. Austin

Dutch footballer

USS Heed

Start-Class Alaska articles

Peter Pett, at Deptford Dockyard

Alaska articles by importance

Karjalainen, Kyosti

PPP2R2C

A-Class Alaska articles

NEFM

Andy Coen

United Kingdom

Eric Albertson

Percy L. Wendell

John

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID , which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. This gene encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas. Two transcripts encoding different isoforms have been identified.

Cheetah (1989 film)

Dcirovic

Who's in the House

Jackson

Association of Mid-Continent Universities

Bethlehem, Pennsylvania

Supernova/カルマ

Karmio, Greece

Tara Bai

Butler, Margaret, Lady

Card

Long Land

Bill Seddon

Healy (Metra)
true

* Emilio Surita
* Marcos Chiesa
* Tutinha

Salzwedel, Dave

Central Intelligence Agency domestic surveillance operations

Rene Chapdelaine

AMCU-8

Democratic nominee for South Carolina Superintendent of Education

Entertainment Weekly

NDUFS4

タチコマ robot

Kim Hui-su

Theanphibian

PI4KA

Chapdelaine, Rene

Hmainsbot1

Eagles

Abraham Broidman Kuttenlon

Reiter, Howard Roland

Potomski, Barry

Kilkenny Castle, County Kilkenny, Ireland

Print

B-Class Alaska articles

The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

William Boleyn

Fujiwara Motoo

Boston, Massachusetts

Broken Family Band

Lásdikas, Greece

Roman Catholic archbishops of Pisa

Bo Knows Bo

Helpful Pixie Bot

Chicago, Illinois 60639

J. W .Walker & Sons Ltd

Airwolf themes

American sports administrator

The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.

Manufactured Gas Plants

TSN

Lásdikas

Lee Seok-gi

T-55A and T-55AM2B

Prosperosity

RjwilmsiBot

The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.

EED

Citation bot 1

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a caspase-3 substrate, and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis. This encoded protein can form a complex with the Golgi matrix protein GOLGA2, and this complex binds to the vesicle docking protein p115. Several alternatively spliced transcript variants of this gene have been identified, but their full-length natures have not been determined.

GA-MHR

Jackboogie

TonyTheTiger

Lead pencil

Bovineboy2008

University of Northern Iowa

AP3B1

two passengers, or two litters

Kenneth Vaisman Litchman

Erik Tarloff

Potomac River Flotilla

William Leckonby

Claremont, New Hampshire

Shin Pyong-ha

TRO (gene)

Meiguoren

John Baldecchi

John of Reading

present

3–0 (NCAA D-II playoffs)

Elgin Womack

Dan Howers

Tate pictured in Epitome 1934, Lehigh yearbook

PPP3CB

HomeServices of America

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L6E family of ribosomal proteins. It is located in the cytoplasm. The protein can bind specifically to domain C of the tax-responsive enhancer element of human T-cell leukemia virus type 1, and it has been suggested that the protein may participate in tax-mediated transactivation of transcription. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

date unknown

FA-Class Alaska articles

Necropsies

Pânico na Band

Sunrise Ski

AXIN2

Royal Air Force air marshals
John Barker

Leckonby, William B.; Leckonby, Bill

Danny Tull

David Eppstein

Beyond My Ken

Cheetah

Western Illinois University
Northern Iowa Panthers

Swedish ice hockey player

Sports Network FCS Poll

men

VICA

Martin R. Smith

Brainiacal

161–62 (golf)

Morphologist

Koumánis

Navy Blue Gold

T-8th

Edge Lane

American producer

KCNJ5

Land and houses

Higgins, Kevin

Ball State

Warren Bradley

Citation bot

Tate, Albert Austin; Tate, Albert A.

EXOC4

Tara bai

85–53–5 (football)

2–2 (NCAA D-I playoffs)

Pânico na TV

Barker, John Lindsay

Roman Catholic archbishops of Genoa

PCK1

ArmbrustBot

"Karma/Supernova"

English

Portuguese

Unassessed Alaska articles

Democratic

Prendergast, Leo

Top-importance Alaska articles

Dave Salzwedel

Saskatchewan Rebellion

Salzwedel

at Boston, Massachusetts

Father Brian and The Fun Lovin' Cardinals - Who's in the House.ogg

Potomski

Leo

Hank Small

FrescoBot

MYO9B

Left

Tassedethe

5–21–1

Glen Harmeson (football coach)

Margaret Boleyn

Higgins

Positive link

Speedwell

Canadian ice hockey player

Stan Kyles

Pumpie

5–2–1

as built

Barry Potomski

Karjalainen

Wolvercote Platform railway station

Jim

Rankings from final Sports Network poll

SGGH

"Who's In The House"

Abductive

We Are Born

Thomas Burstyn

Lásdika, Greece

T–6th

Fernando

Clinton Ransey

small

Lady Boleyn

Ray Salters

Giving You Everything

Reiter pictured in The Epitome 1914, Lehigh yearbook

PON3

PRKAG1

UMass

Bduke

Mansfield Recreation Reserve

after 1607 rebuild

Glick pictured in The Epitome 1922, Lehigh yearbook

Danlindner

Bob Crawford

Magioladitis

PFN2

The Black Swan (album)

London and L.A. in 2007

Small, Hank

This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. By associating with these subunits only, the Transducin alpha subunit will remain active for longer. This will increase the amount of time of visual excitation.

This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.

XRCC2

Some People Have Real Problems US cover.jpg

Cool (producer)

Prendergast

Some People Have Real Problems

Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally related genes.

This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.

Seddon, Bill

Reiter, Howard R.

Wwoods

Paul Stewart

Ser Amantio di Nicolao

Lady Margaret Butler

Colour the Small One

Yeonbang Movies

Jweiss11

Hofstra

G. P. Putnam's Sons

Wilbur Wade

Wilbur Card

HMS Dreadnought (1592)

John Barker (RAF officer)

Brooks

George

Xqbot

Cydebot

Phosducin

Global Dance Tracks

Kevin Higgins

Matessi, Greece

Schlossberg

T-54/55 operators and variants

Alaska articles by quality

PEX14

Bill

3–15–1 (football)

Journalists killed while covering military conflicts

South Korea

National Security Agency images

University of Illinois at Chicago

James A. Baldwin (football coach)

Kyosti Karjalainen

yesbowl=yes

Lemnaminor

Antimalarial drugs

Hoban, George

link

John Whitehead (American football)

Wenli

Lee Mun-woong

TAF15

Mld74

Rex, Jim

Gordon Jackson

Pat Vuyancih

ZTS Martin

Lasdikas, Greece

Gallery of Hieracium anatomy

Eastern Illinois Panthers
Eastern Illinois University

Karmi, Greece

Good Olfactory

1–3 (NCAA D-I playoffs)

Wisconsin–Green Bay

Los Angeles Soccer Club

Alan Wambold

W. W. Card

Toy's FactoryTFCC-89153

Matessi

Cooley, Michael T.
Atlanta, Georgia

sia

Leckonby

Pete Lembo

Uniformed services of the United States

Madisonave620

Medical Materiel

American baseball player and coach

Jin (Korean history)

Chromatin assembly factor I is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.

Kyles at Brewers spring training in 2011

T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells . Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor gamma locus. The gamma locus includes V , J , and C segments. During T cell development, the gamma chain is synthesized by a recombination event at the DNA level joining a V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random addition of nucleotides by terminal deoxynucleotidyltransferase. Several V segments of the gamma locus are known to be incapable of encoding a protein and are considered pseudogenes. Somatic rearrangement of the gamma locus has been observed in T cells derived from patients with T cell leukemia and ataxia telangiectasia.

Sequenceome

Bgwhite

University of Wisconsin–Green Bay

MMP16

Towers hall

Northern Iowa

Malo malo malo malo

Lásdika

Reiter

Metra

Rex

Kyles

ZAK

Vannuysguy

Supernova -- Karma .jpg

at the Boston Navy Yard

HMS Antelope (1581)

Bakri

Faisal.akeel

Israel Aerospace Industries

Paine Ellsworth

PTPRM

Georgewilliamherbert

→ San Jose Hawks

Art Nouveau Magazine

William

Programa Pânico

Dudley Ward

Lynah, James

NAGA (gene)

Tumor necrosis factor alpha is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene.

RPL6

Jacob Bakri

Stub-Class Alaska articles

Small nuclear ribonucleoprotein polypeptide F

Muro Bot

HMS Dreadnought (1614)

RGS3

SF3A2

Jacob

Stan

USS Hendry

NIN (gene)

Anthony Boleyn

Royal Ceylon Air Force

ARD1A

John Martin

EIF3I

Nford24

Koumánis, Greece

Boghog

Lembo

Rjwilmsi

CHAF1B

HMS Antelope (1618)

This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif . This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Marty Sweeney
Steve Corbin

Everyking

screw-propelled

A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome . At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX . RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined.

Zimbabwe at the Olympics

Julian

List of best-selling CDs (Brazil)

American football player and coach, basketball coach

Autodyne reception

Schlossberg, Julian

Harding

Miym

CCL3L1

One

AMCU-8 Regular Season Champions

one 12-pounder howitzer

Hmains

Hotwiki

Proteins of the matrix metalloproteinase family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene produces at least two transcripts, one which encodes a membrane-bound form and another a soluble form of the protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.

Koumáni, Greece

Small, Henry

Jabaway

Tate, A. Austin

USS Trefoil (1865)

American football coach

Lasdika, Greece

Sir William Boleyn

LPP (gene)

Hoban

Chapdelaine

Valparaiso University

Coen

Gunki monogatari

WhisperToMe

Delaware

Gordon Jackson (businessman)

BOTijo

Eric Mudd

Karmion, Greece

Barry

W.W. Card

Flowerpotman

Anthony Appleyard

WHSC1

Eric Styles

Staufen is a member of the family of double-stranded RNA -binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum , implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.

History of the solar system

Undrafted

41–29

Barker

Vince Richards
Eddie Bryant

JQF

Kyles, Stan

Amhlaw

Tate

Unordered factorization

Stroud Union HS
NCAA Division II Championship

Swiftsure

Kooijman Dick

Wisconsin–Green Bay Phoenix

Lost, 1624

Health Care Procedure Coding System

WillowW

Glick, Frank

Roller Weblogger

Alice Boleyn

Sweet Sixteen vs. Navy

imp

The Problem Of The Wire Cage

Hersey Strong

TRG@

Ohwell32

Cooley pictured in Epitome 1965, Lehigh yearbook

Laurenece Mark

Livingston, New Jersey

"Planetarium"

VLGR1

NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II .

Wolvercote, Oxfordshire

DMahalko

CACNB2

James Lynah

Missionary

LMBR1

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, which are known to be involved in the homologous recombination and repair of DNA. This protein forms a complex with several other members of the RAD51 family, including RAD51L1, RAD51L2, and XRCC2. The protein complex formed with this protein has been shown to catalyze homologous pairing between single- and double-stranded DNA, and is thought to play a role in the early stage of recombinational repair of DNA. Several alternatively spliced transcript variants of this gene have been described, but the biological validity of some of them has not been determined.

Illinois Chicago

KCNB1

Jackson, Gordon

DarknessBot

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

PPP3R1

US Army recognition poster

John Lindsay

HMS Didon

Atzori

one 30-pounder Parrott rifle

Simon School of Business

This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases.

White pictured in Epitome 1980, Lehigh yearbook

* Bell XV-3
* Fairey Jet Gyrodyne
* CarterCopter

AMCU-8 Tournament Champions

COPS4

RAD51L3

Compound gyroplane

Whitehead

Tevildo

Armchair QB

Summit, Hill, Pennsylvania

Merck, Finck & Co.

Hoban pictured in Epitome 1916, Lehigh yearbook

Shawn Hood

Acwbuff276

Reclaim Australia: Reduce Immigration

John Boleyn

htafii18/htafii28 heterodimer crystal structure with bound pcmbs

RTC

D-DOC

Addbot

R'n'B

Eastern Illinois

Mike

SFRS5

KristinaHanspers

132nd overall

Bob Smeaton

Solarra

Dysplasis spondyloepiphysaria congenita

AvicBot

MADD (gene)

MusikAnimal

Trimpe

GORASP1

ProudGamecock

Alex Avery (politician)

Pittsburgh, Pennsylvania