Zinc finger protein 106 homolog is a protein that in humans is encoded by the ZFP106 gene.

Mid-State Sisters of Skate (MSSOS) is a women's flat track roller derby league based in Stevens Point, Wisconsin. Founded in 2010, the league consists of two travel teams which play teams from other leagues. Mid-State is a member of the Women's Flat Track Derby Association (WFTDA).

PDZ and LIM domain protein 2 is a protein that in humans is encoded by the PDLIM2 gene.

Crisaborole (trade name Eucrisa) is a nonsteroidal topical medication used for the treatment of mild-to-moderate atopic dermatitis (eczema) in people two years or older. It was approved by U.S. Food and Drug Administration on Dec 14, 2016.

"Debout Congolais" (Kongo: Telama besi Kongo; English: Stand up, Congolese, lit. Arise Congolese) is the national anthem of the Democratic Republic of the Congo. It was originally adopted in 1960 upon independence from Belgium, but was replaced by "La Zaïroise" when Congo changed its name to Zaire in 1971. It was finally reinstated when Congo was reorganized in 1997. The words are by Joseph Lutumba and the music is composed by .

Lithuanian nationality law operates on the jus sanguinus principle, whereby persons who have a claim to Lithuanian ancestry, either through parents, grandparents, great-grandparents may claim Lithuanian nationality.. Citizenship may also be granted by naturalization. Naturalization requires a residency period, an examination in the Lithuanian language, examination results demonstrating familiarity with the Lithuanian Constitution, a demonstrated means of support, and an oath of loyalty. A right of return clause was included in the 1991 constitution for persons who left Lithuania after its occupation by the Soviet Union in 1940 and their descendants. Lithuanian citizens are also citizens of the European Union and thus enjoy rights of free movement and have the right to vote in elections for the European Parliament.

GDP-fucose transporter 1 is a protein that in humans is encoded by the SLC35C1 gene. Defects can be associated with Congenital disorder of glycosylation type IIc.

YLP motif-containing protein 1 is a protein that in humans is encoded by the YLPM1 gene.

All-trans-retinol 13,14-reductase is an enzyme that in humans is encoded by the RETSAT gene. Alternative names:
* All-trans-13,14-dihydroretinol saturase Short name:
* RetSat
* PPAR-alpha-regulated and starvation-induced gene protein

Phosphorylated adapter RNA export protein is a protein that in humans is encoded by the PHAX gene.

In moral philosophy, deontological ethics or deontology (from Greek δέον, deon, "obligation, duty")is the normative ethical theory that the morality of an action should be based on whether that action itself is right or wrong under a series of rules, rather than based on the consequences of the action. It is sometimes described as "duty-" or "obligation-" or "rule-" based ethics, because rules "bind one to one's duty". Deontological ethics is commonly contrasted to consequentialism, virtue ethics, and pragmatic ethics. In this terminology, action is more important than the consequences.

CAAX prenyl protease 2 is an enzyme that in humans is encoded by the RCE1 gene. This gene encodes an integral membrane protein which is classified as a member of the metalloproteinase family. This enzyme is thought to function in the maintenance and processing of CAAX-type prenylated proteins.

Nucleoporin p58/p45 is a protein that in humans is encoded by the NUPL1 gene. This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

"A Fox, a Rabbit, and a Cabbage" is the ninth and penultimate episode of the first season of the FX anthology series Fargo. The episode aired on June 10, 2014 in the United States on FX. It was written by series creator and showrunner Noah Hawley and directed by Matt Shakman. The episode title refers to a variation of the fox, goose and bag of beans puzzle. "A Fox, a Rabbit, and a Cabbage" received critical acclaim, and was seen by 1.90 million viewers.

Kingston Town (31 August 1976 – March 1991) was an outstanding Australian bred Thoroughbred racehorse who once held a record three Cox Plates and 11 other Group One races in a career spanning from 1979 to 1982. In 1980 he was awarded the honour of being the Australian Champion Racehorse of the Year. He was by Bletchingly, later a Leading sire in Australia, his dam, Ada Hunter (GER) was by Andrea Mantegna (FR). Ada Hunter was the dam of nine foals, but Private Thoughts (a brother to Kingston Town) was her only other stakes winner. She was later exported to the United States. Kingston Town was bred by David Hains, who sold a share in him to G. Monsborough and his wife after the horse failed to reach his reserve as a yearling.

Gregory Shantha Kumar Francis (B.Th., PGDip.P&CC), was an Anglican Bishop of Kurunegala, Sri Lanka. Gregory Shantha Kumar Francis was born in 1955 in the village of Polgahawela, Sri Lanka. He is an upcountry Tamil, and fluent in Sinhala, English and Tamil. Francis was appointed as deacon in 1978, receiving his Bachelor of Theology from the University of Serampore the same year. In 1980 he obtained a postgraduate diploma in pastoral and clinical counselling from of Psychology, Colombo and was ordained as a priest in the Church of Ceylon. He was the chaplain at Hillwood College, Kandy (1993-2000), Trinity College, Kandy (2001-2004). Francis also obtained a higher diploma in comprehensive drug abuse prevention and counselling from the Anti Narcotic Association of Sri Lanka. On 7 November 2010 Rowan Williams, Archbishop of Canterbury, appointed Francis as the fifth Bishop of Kurunegala in the Church of Ceylon, succeeding retired Bishop Kumara Illangasinghe. In 2012, Francis was nominated by the International Counter Narcotic Association to be a consultant on rehabilitation and counselling. On 6 January 2015 the Archbishop of Canterbury, Justin Welby, announced that Francis had resigned as Bishop of Kurunegala. In a statement by Francis he advised that he had been threatened by Tamil diaspora groups opposing his stand for a unitary state and the sovereignty of the country. Francis is married to Priyadharshin and has two sons, Prabath and Pramith.

The Host is a romance novel by Stephenie Meyer. The book is about Earth, in a post apocalyptic time, being invaded by a parasitic alien race, known as "Souls", and follows one Soul's predicament when the consciousness of her human host refuses to co-operate with the takeover of her body. The Host was released on May 6, 2008, with an initial print run of 750,000 copies. An international version of the novel was released on April 2, 2009, in the United Kingdom, Ireland, Indonesia, the Philippines, Australia and Hong Kong by the UK publishing division. It was translated into many languages.

Importin-11 is a protein that in humans is encoded by the IPO11 gene.

The Cancer Act 1939 is an Act of Parliament of the United Kingdom passed in 1939 to make further provision for the treatment of cancer, to authorise the Minister of Health to lend money to the National Radium Trust, to prohibit certain advertisements relating to cancer, and for purposes connected with the matters aforesaid. The Act does not apply in Northern Ireland. As of December 2014, the sole remaining provision is in respect of advertising to treat or cure cancer, all other provisions having been repealed or subsumed into other legislation.

Protocadherin-12 is a protein that in humans is encoded by the PCDH12 gene. This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no effect on cell migration or growth.

Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure, and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Lamin B, along with heterochromatin, is anchored to the inner surface of the nuclear membrane by the lamin B receptor.

Heavy is a 1995 American drama film written and directed by James Mangold, and starring Liv Tyler, Pruitt Taylor Vince, Shelley Winters, and Deborah Harry. The plot focuses on an unhappy overweight cook (Vince) whose life is changed after an enchanting college drop-out (Tyler) begins working as a waitress at his and his mother's roadside tavern. The film explores themes of loneliness, false hope, unrequited love, and self-worth.

Histone-lysine N-methyltransferase NSD3 is an enzyme that in humans is encoded by the WHSC1L1 gene. This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. The function of the protein has not been determined. Two alternatively spliced variants have been described. The WHSC1L1 gene is amplified in several cancers, including lung cancer and head and neck cancer, and may play a role in carcinogenesis.

Programmed cell death protein 7 is a protein that in humans is encoded by the PDCD7 gene. This gene encodes a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signalling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells.

Mory Koné (born 21 April 1994) is a French footballer who plays for Troyes. He plays as a central defender. Koné is of Ivorian descent and has represented both his birth and ancestral nation at international level. He has represented France at under-17 and under-18 level, while he represented Ivory Coast at the 2011 FIFA U-17 World Cup.

Vacuolar protein sorting-associated protein 13D is a protein that in humans is encoded by the VPS13D gene. This gene encodes a protein belonging to the vacuolar-protein-sorting-13 gene family. In yeast, vacuolar-protein-sorting-13 proteins are involved in trafficking of membrane proteins between the trans-Golgi network and the prevacuolar compartment. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode distinct isoforms.

SEC14-like protein 1 is a protein that in humans is encoded by the SEC14L1 gene. The protein encoded by this gene belongs to the SEC14 cytosolic factor family. It has similarity to yeast SEC14 and to Japanese flying squid RALBP which suggests a possible role of the gene product in an intracellular transport system.

p21-activated protein kinase-interacting protein 1 is an enzyme that in humans is encoded by the PAK1IP1 gene.

Mobb Deep was an American hip hop duo from Queensbridge, Queens, New York. The group consisted of Havoc and Prodigy, and were a hardcore East Coast hip hop group. They were known for their dark, hardcore delivery as exemplified in "Shook Ones (Part II)." Mobb Deep became one of the most successful rap duos in hip hop, having sold over 3 million records. Three of their notable albums were The Infamous (1995), Hell On Earth (1996) and Murda Muzik (1999), and their top hits include "Shook Ones, Pt. II", "Survival of the Fittest" and "Hell on Earth".

Glutamine-dependent NAD(+) synthetase is an enzyme that in humans is encoded by the NADSYN1 gene. Nicotinamide adenine dinucleotide (NAD) is a coenzyme in metabolic redox reactions, a precursor for several cell signaling molecules, and a substrate for protein posttranslational modifications. NAD synthetase (EC 6.3.5.1) catalyzes the final step in the biosynthesis of NAD from nicotinic acid adenine dinucleotide (NaAD).

Pyrgoteles is an unplaced genus of bugs in the family Fulgoridae: species can be found in Africa.

28S ribosomal protein S17, mitochondrial is a protein that in humans is encoded by the MRPS17 gene. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 1p, 3p, 6q, 14p, 18q, and Xq.

Leo Gudas (born May 20, 1965) is a Czech former professional ice hockey player. He is the father of Philadelphia Flyers defenseman Radko Gudas. Leo Gudas is coach for Sport Club Csíkszereda.

Protocadherin beta-7 is a protein that in humans is encoded by the PCDHB7 gene. This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell a

John Alan Means (born April 24, 1993) is an American professional baseball pitcher for the Baltimore Orioles of Major League Baseball (MLB). He made his MLB debut in 2018.

Mitogen-activated protein kinase 4 is an enzyme that in humans is encoded by the MAPK4 gene. Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus where it phosphorylates nuclear targets. The Arabidopsis MAPK4 is important in signalling

The tōyō kanji, also known as the Tōyō kanjihyō (当用漢字表, "list of kanji for general use") are the result of a reform of the Kanji characters of Chinese origin in the Japanese written language. They were the kanji declared "official" by the Japanese Ministry of Education (文部省) on November 16, 1946. They were replaced in 1981 by the Jōyō kanji.

In moral philosophy, deontological ethics or deontology (from Greek δέον, deon, "obligation, duty")is the normative ethical theory that the morality of an action should be based on whether that action itself is right or wrong under a series of rules, rather than based on the consequences of the action. It is sometimes described as "duty-" or "obligation-" or "rule-" based ethics, because rules "bind one to one's duty". Deontological ethics is commonly contrasted to consequentialism, virtue ethics, and pragmatic ethics. In this terminology, action is more important than the consequences. It is an ethical framework that depends on the predefined sets of rules and policies for the proper functioning of a system in the environment. The deontology is simply based on the checklist which includes certain rules to be followed while performing a particular task. According to this framework, the work is considered virtuous only if this checklist is completed.This procedure is very simple to implement and understand. Minimum time is consumed to decide between right and wrong. However, its simplicity ignores the consequences of the decision taken under this approach. The term deontological was first used to describe the current, specialised definition by C. D. Broad in his 1930 book, Five Types of Ethical Theory Older usage of the term goes back to Jeremy Bentham, who coined it before 1816 as a synonym of Dicastic or Censorial Ethics (i.e. ethics based on judgement).The more general sense of the word is retained in French, especially in the term code de déontologie (ethical code), in the context of professional ethics. Depending on the system of deontological ethics under consideration, a moral obligation may arise from an external or internal source, such as a set of rules inherent to the universe (ethical naturalism), religious law, or a set of personal or cultural values (any of which may be in conflict with personal desires).

SLIT-ROBO Rho GTPase-activating protein 1 is an enzyme that in humans is encoded by the SRGAP1 gene.

The 2019 Advance Auto Parts Clash was a Monster Energy NASCAR Cup Series race held on February 10, 2019, at Daytona International Speedway in Daytona Beach, Florida. Contested over 59 laps, shortened from 75 due to rain, it was the first exhibition race of the 2019 Monster Energy NASCAR Cup Series season.

Histone H2B type 2-F is a protein that in humans is encoded by the HIST2H2BF gene.

28S ribosomal protein S16, mitochondrial is a protein that in humans is encoded by the MRPS16 gene. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S16P family. The encoded protein is one of the most highly conserved ribosomal proteins between mammalian and yeast mitochondria. Three pseudogenes (located at 8q21.3, 20q13.32, 22q12-q13.1) for this gene have been described.

Arthur Ocean Waskow (born Arthur I. Waskow; 1933) is an American author, political activist, and rabbi associated with the Jewish Renewal movement.

Vesicular glutamate transporter 1 (VGLUT1) is a protein that in humans is encoded by the SLC17A7 gene. The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family.

Ubiquitin-conjugating enzyme E2 R2 is a protein that in humans is encoded by the UBE2R2 gene. Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

Black Friday is a 1940 American science fiction gangster psychological thriller starring Boris Karloff. Béla Lugosi, although second-billed, has only a small part in the film and does not appear with Karloff. Writer Curt Siodmak would revisit this theme again in Donovan's Brain (1953) and Hauser's Memory (1970).

The Toccata and Fugue in F Major, BWV 540 is an organ work written by Johann Sebastian Bach. The toccata is thought to be written after 1714, and the fugue before 1731.

Zinc finger protein 268 is a protein that in humans is encoded by the ZNF268 gene.

Muscleblind-like protein 3 is a protein that in humans is encoded by the MBNL3 gene.

Protocadherin-7 is a protein that in humans is encoded by the PCDH7 gene. This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell–cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails.

Dr H.A. Hellyer , a British scholar and analyst, writes on the politics of the modern Arab world, religion and politics in Europe and internationally, majority-minority relations, security issues and the Muslim world - West relations. He is a senior nonresident fellow at the Atlantic Council's Center for the Middle East, and associate fellow at the Royal United Services Institute. Previously a nonresident fellow at the Brookings Institution's Foreign Policy section, and he was also Democracy Non-Resident Fellow for the academic year 2014 - 2015 at the John F. Kennedy School of Government of Harvard University.

MKL/myocardin-like protein 2 is a protein that in humans is encoded by the MKL2 gene. Members of the myocardin family bind to the transcription factor serum response factor (SRF) and act as coactivators controlling genes of relevance for myogenic differentiation and motile function.

Maspardin is a protein that in humans is encoded by the SPG21 gene. The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4.

SOX12 is a protein that in humans is encoded by the SOX12 gene. Sox12 belongs to the SoxC group of Sox family of transcription factors, together with Sox4 and Sox11. Sox12-null knockout mice appear normal, unlike Sox4 or Sox11 knockout mice. This probably comes from functional redundancy with Sox4 and Sox11. Sox12 is a weaker activator than both Sox4 and Sox11 in mouse. Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.

Ubiquitin carboxyl-terminal hydrolase 34 is an enzyme that in humans is encoded by the USP34 gene.

Receptor-type tyrosine-protein phosphatase H is an enzyme that in humans is encoded by the PTPRH gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. The extracellular region contains eight fibronectin type III-like repeats and multiple N-glycosylation sites. The gene was shown to be expressed primarily in brain and liver, and at a lower level in heart and stomach. It was also found to be expressed in several can

Alpha-1-acid glycoprotein 1 is a protein that in humans is encoded by the ORM1 gene. This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression.

This is a list of notable events in country music that took place in the year 2006.

William Clifford Musselman (August 13, 1940 – May 5, 2000) was an American basketball coach in the NCAA, the ABA, the WBA, the CBA and the NBA. He was known for his trademark intensity, once being quoted as saying, "Defeat is worse than death” because “you have to live with defeat."

Félix Sesúmaga Ugarte (born 12 October 1898 – 24 August 1925) was a Spanish (Basque) footballer during the 1910s and the 1920s. Born in Lejona, Vizcaya, he played as a forward for Arenas Club de Getxo, FC Barcelona, Racing de Sama de Langreo, Athletic Bilbao and Spain. Sesúmaga won the Copa del Rey three times with three clubs and also played in two successive finals for two clubs. In 1920 Sesúmaga was also a member of the very first Selección that played at the Olympic Games in Belgium. He scored twice as Spain beat the Netherlands 3–1 in the play-off for the silver medal. He played 8 times for Spain, scoring 4 goals between 1920 and 1923.

Protein disulfide-isomerase TMX3 is an enzyme that in humans is encoded by the TMX3 gene.

Ras-associating and dilute domain-containing protein is a protein that in humans is encoded by the RADIL gene.

Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 is an enzyme that in humans is encoded by the HS3ST3B1 gene.Heparan sulfate biosynthetic enzymes are key components in generating myriad distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity ( HS3ST3A1). The Sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1 and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta.

Signal-transducing adaptor protein 2 is a protein that in humans is encoded by the STAP2 gene. This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants.

Rap1 GTPase-GDP dissociation stimulator 1 is an enzyme that in humans is encoded by the RAP1GDS1 gene.

THAP domain-containing protein 4 is a protein that in humans is encoded by the THAP4 gene.

Ghislaine Landry (born April 27, 1988) is a Canadian rugby union player. She won a gold medal at the 2015 Pan American Games as a member of the Canadian women's rugby sevens team. As of the 2016-17 season, Landry succeeded Jen Kish as captain of the national sevens. On 20 October 2018, Landry became the first woman to hit the 1,000 point milestone in the women's sevens World Series. In 2016, Landry was named to Canada's first ever women's rugby sevens Olympic team, which won the bronze medal in a match against Great Britain. In 2017, Landry moved into first place all-time in HSBC World Rugby Women's Sevens Series scoring with 706 points. Landry attended Saint Francis Xavier University.

Gerace (Italian pronunciation: [dʒeˈraːtʃe]; Greek: Hierax, Gerakion) is a town and comune in the Metropolitan City of Reggio Calabria, Calabria, southern Italy.Gerace is located some 10 kilometres (6 mi) inland from Locri, yet the latter town and the sea can be seen from Gerace's perch atop a 500-metre (1,600 ft) vertical rock. The town stands on a hill formed of conglomerates of sea fossils from 60 millions years ago. It is inscribed into I Borghi più belli d'Italia list.

Solute carrier family 2, facilitated glucose transporter member 9 is a protein that in humans is encoded by the SLC2A9 gene. This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene. SLC2A9 has also recently been found to transport uric acid, and genetic variants of the transporter have been linked to increased risk of development of both hyperuricemia, gout and Alzheimer's disease.

Solute carrier family 22 member 7 is a protein that in humans is encoded by the gene SLC22A7. The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described.

Mark F. Miller (born February 1, 1943) is a Democratic member of the Wisconsin Senate. Miller has represented the 16th District since 2005. He served as Minority Leader from 2011 to 2012. He was previously a member of the Wisconsin State Assembly, representing the from 1999 through 2005.

Interleukin-20 receptor beta chain is a protein that in humans is encoded by the IL20RB gene.

Ubiquitin-like protein 5 is a protein that in humans is encoded by the UBL5 gene. It has been shown that in C. elegans mitochondria treated to lower expression of certain electron transport chain proteins during the L3/L4 stage, its expression levels is higher leading to increased lifespans. Ubiquitin-like proteins (UBLs) are thought to be reversible modulators of protein function rather than protein degraders like ubiquitin (MIM 191339).[supplied by OMIM]

Protocadherin beta-7 is a protein that in humans is encoded by the PCDHB7 gene. This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. The transcript for this particular family member uses more than one polyadenylation site.

Ntozake Shange ( EN-toh-zah-kee SHAHNG-gay; October 18, 1948 – October 27, 2018) was an American playwright and poet. As a Black feminist, she addressed issues relating to race and Black power in much of her work. She is best known for her Obie Award-winning play, For Colored Girls Who Have Considered Suicide / When the Rainbow Is Enuf. She also penned novels including Sassafrass, Cypress & Indigo (1982), Liliane (1994), and Betsey Brown (1985), about an African-American girl runaway from home. Among Shange's honors and awards were fellowships from the Guggenheim Foundation and Lila Wallace Reader's Digest Fund, and a Pushcart Prize. In April 2016, Barnard College announced it had acquired Shange's archive. Shange lived in Brooklyn, New York.

Rho-related BTB domain-containing protein 1 is a protein that in humans is encoded by the RHOBTB1 gene. The protein encoded by this gene belongs to the Rho family of the Ras superfamily of small GTPases. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate transcriptional splice variants have been characterized.

Otoraplin is a protein that in humans is encoded by the OTOR gene. The protein encoded by this gene is secreted via the Golgi apparatus and may function in cartilage development and maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness. This gene is a member of the melanoma-inhibiting activity gene family. In addition, alternate polyA sites exist for this gene.

Hexagonal chess refers to a group of chess variants played on boards composed of hexagon cells. The best known is Gliński's variant, played on a symmetric 91-cell hexagonal board. Since each hexagonal cell not on a board edge has six neighbor cells, there is increased mobility for pieces compared to a standard orthogonal chessboard. (E.g., a rook has six natural directions for movement instead of four.) Three colours are typically used so that no two neighboring cells are the same colour, and a colour-restricted game piece such as the orthodox chess bishop usually comes in sets of three per player in order to maintain the game's balance.

NEDD4 family-interacting protein 2 is a protein that in humans is encoded by the NDFIP2 gene.

UDP-N-acetylhexosamine pyrophosphorylase is an enzyme that in humans is encoded by the UAP1 gene.

KIAA1166 is a human gene.

NACHT, LRR and PYD domains-containing protein 12 is a protein that in humans is encoded by the NLRP12 gene. NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP12, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003).[supplied by OMIM]

William Alexander Sutherland (December 1, 1876 – May 21, 1969) was a lawyer and an American football coach. He served as the head football coach at New Mexico State University–then known at New Mexico A&M–in 1900. Sutherland was an 1898 graduate of New Mexico A&M and served as a lawyer in Las Cruces.

High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A is an enzyme that in humans is encoded by the PDE8A gene. Work by Sebastiaan Bol et al. showed that 5 different transcript variants and their corresponding isoforms are expressed in human macrophages, and suggests that this protein may be required by HIV-1 for its replication.

The Music Machine was an American rock band formed in Los Angeles, California in 1966. Fronted by chief songwriter and lead vocalist Sean Bonniwell, the band cultivated a characteristically dark and rebellious image reflected in an untamed musical approach. Sometimes it made use of distorted guitar lines and hallucinogenic organ parts, punctuated by Bonniwell's distinctively throaty vocals. Although they managed to attain national chart success only briefly with two singles, the Music Machine is today considered by many critics to be one of the groundbreaking acts of the 1960s. Their style is now recognized as a pioneering force in proto-punk; yet within a relatively short period of time, they began to employ more complex lyrical and instrumental arrangements that went beyond the typical garage band format. In 1965, the band came together as a folk rock trio known as the Raggamuffins, before expanding to the quintet that was later rechristened the Music Machine. The group was known for their style of dress, clothing themselves in all-black attire. In 1966, the Music Machine was signed to Original Sound, and released its first single "Talk Talk" in the latter half of the year, with it reaching the Top 20 of the Billboard Hot 100. Their debut album (Turn On) The Music Machine and the moderate hit "The People in Me" followed. The band's original lineup fragmented in late 1967 after managerial and financial disputes. Bonniwell reassembled the group under the name The Bonniwell Music Machine. In 1968, a second album, The Bonniwell Music Machine appeared, but the group disbanded in early 1969.

Ras-related protein Rab-5C is a protein that in humans is encoded by the RAB5C gene. RAB5C belongs to the Ras-related protein family.

The football sporting event at the 1917 Far Eastern Championship Games was participated by three nations; Philippines, China and football debutant and hosts Japan. China was represented by South China A.A. and Japan was represented by a selection from the Tokyo Higher Normal School.

Kelch-like protein 8 is a protein that in humans is encoded by the KLHL8 gene.

Zinc finger and BTB domain-containing protein 7B is a protein that in humans is encoded by the ZBTB7B gene.ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes (e.g. COL1A1; MIM 120150) and has a role in development.[supplied by OMIM]

The Lost Provinces were relatively inaccessible regions of North Carolina in the 19th and early 20th centuries, under-served by roads and railroads. In the mountainous northwest corner of the state, west of the Eastern Continental Divide. Ashe, Alleghany and Watauga counties in the New River basin were cut off from the rest of the state by the high Blue Ridge Mountains. The area's mountainous topography caused these counties to be most closely connected to Smyth and Grayson counties in Virginia, and to Johnson and Carter counties in Tennessee. The first highway to connect the area to points east was the Blowing Rock Turnpike. Started in 1911, it ran to Lenoir in Caldwell County. In 1914 a railroad was built to connect Ashe County to Abingdon, Virginia. After 1921 North Carolina Highway 16

The American Shoal Light is located east of the Saddlebunch Keys, just offshore from Sugarloaf Key, close to Looe Key, in Florida, United States. It was completed in 1880, and first lit on July 15, 1880. The structure was built to the same plan and dimensions as the Fowey Rocks lighthouse, completed in 1878.

Keywan Karimi (Persian: کیوان کریمی‎ ; born 21 September 1985) is an Iranian independent filmmaker of Kurdish origin. He graduated with ad degree communication studies form the . Karimi began his work with a series of short documentary films which were a critique of human life in contemporary Iran. He was sentenced to six years in prison and 223 lashes because of the content of his films.

Ectoderm-neural cortex protein 2 is a protein that in humans is encoded by the KLHL25 gene.

The Normans in Ireland, or Hiberno-Normans, were a group of Normans who invaded the various realms of Gaelic Ireland. They arrived from the Kingdom of England and Wales from the 12th century onwards and established themselves as a feudal aristocracy and merchant oligarchy in the Lordship of Ireland which existed throughout the High Middle Ages and Late Middle Ages. They can in many ways be seen as a branch of the Normans in England and Wales. Most of the Normans eventually became Gaelicised, especially in the West. For instance, in Gaelic Munster where Cork was the Norman capital, proven statistically by the dominance of French names and linguistics. These Normans nominally owed their position and claims to territory due to the King of England and were also closely associated with the Gregorian Reform of the Catholic Church in Ireland. Their fortunes took a dip in the 17th century, when they became known as The Old English and much of their caste merged with native Irish Gaels under the denominator of "Irish Catholic." This was because a New English Protestant elite had arrived as a new ruling class in Ireland during the Tudor period. Some Normans opted to assimilate with these Anglo-Irish people. Their descendants live in Ireland to this day and have spread out through the Irish diaspora, but no longer commonly identify as Norman. Some of the most prominent Norman families were the FitzMaurices, FitzGeralds, Burkes and Butlers. One of the most popular Irish surnames, Walsh, derives from the Normans based in Wales who arrived in Ireland as part of this group.

SOX12 is a protein that in humans is encoded by the SOX12 gene. Sox12 belongs to the SoxC group of Sox family of transcription factors, together with Sox4 and Sox11. Sox12-null knockout mice appear normal, unlike Sox4 or Sox11 knockout mice. This probably comes from functional redundancy with Sox4 and Sox11. Sox12 is a weaker activator than both Sox4 and Sox11 in mouse.

Membrane-spanning 4-domains subfamily A member 7 is a protein that in humans is encoded by the MS4A7 gene. This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

General elections were held in Bosnia and Herzegovina on 12 October 2014. Voters elected the national Presidency and House of Representatives, as well as the Presidents and legislatures of the two entities.

Pantothenate kinase 4 is an enzyme (pantothenate kinase) that in humans is encoded by the PANK4 gene. This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues.

A fermata (Italian: [ferˈmaːta]; "from fermare, to stay, or stop"; also known as a hold, pause, colloquially a birdseye or cyclops eye, or as a grand pause when placed on a note or a rest) is a symbol of musical notation indicating that the note should be prolonged beyond the normal duration its note value would indicate. Exactly how much longer it is held is up to the discretion of the performer or conductor, but twice as long is common. It is usually printed above but can be occasionally below (when it is upside down) the note to be extended. When a fermata is placed over a bar or double-bar, it is used to indicate the end of a phrase or section of a work. In a concerto, it indicates the point at which the soloist is to play a cadenza. A fermata can occur at the end of a piece (or movement) or in the middle of a piece. It can be followed by either a brief rest or more notes. Fermata is the Italian name for the sign (𝄐), which in English is commonly called a Pause, and signifies that the note over which it is placed should be held on beyond its natural duration. It is sometimes put over a bar or double bar, in which case it intimates a short interval of silence. Other names for a fermata are corona (Italian), point d'orgue (French), Fermate (German), calderón (Spanish), suspensão (Portuguese).

E3 ubiquitin-protein ligase MARCH6 is an enzyme that in humans is encoded by the MARCH6 gene.

Urbs Reggina 1914, commonly referred to as Reggina, is an Italian football club based in Reggio Calabria. Founded in 1914, they currently play in Serie C, and play their home matches at the 27,763 seater Stadio Oreste Granillo. Their majority shareholder is Mimmo Praticò, former regional president of CONI. He took over control of the club in 2015 after bankruptcy was declared. They are nicknamed the amaranto (amaranth) after their official colours. The club also formerly known as Reggina Calcio as well as A.S.D. Reggio Calabria or S.S.D. Reggio Calabria in 2015–16 season.

Jujhar Khaira (born August 13, 1994) is a Canadian professional ice hockey centre currently playing for the Edmonton Oilers in the National Hockey League (NHL). Khaira was drafted 63rd overall by the Oilers in the 2012 NHL Entry Draft.

"A Fox, a Rabbit, and a Cabbage" is the ninth and penultimate episode of the first season of the FX anthology series Fargo. The episode aired on June 10, 2014 in the United States on FX. It was written by series creator and showrunner Noah Hawley and directed by Matt Shakman. The episode title refers to a variation of the fox, goose and bag of beans puzzle. The episode is set after the one-year ellipsis featured in the previous episode: Lorne Malvo (Billy Bob Thornton) now has a completely new life as a dentist known as "Mick Michaelson". However, his plans are compromised when Lester Nygaard (Martin Freeman) incidentally runs into him. Meanwhile, Gus Grimly (Colin Hanks), now a mailman, is happily married to Molly Solverson (Allison Tolman), whose theory that Lester was involved in the murders finds new supporters in FBI agents Pepper (Keegan-Michael Key) and Budge (Jordan Peele). "A Fox, a Rabbit, and a Cabbage" received critical acclaim, and was seen by 1.90 million viewers.

Casa Padre is a shelter for unaccompanied or separated immigrant minors in custody of the U.S. Office of Refugee Resettlement, a division of Health & Human Services, located in Brownsville, Texas . The building was formerly a Walmart store. The center is run by the nonprofit group Southwest Key Programs under contract from the federal government. Casa Padre is the largest licensed childcare facility in the United States, housing approximately 1,500 youths. According to the Internal Revenue Service, the group houses approximately 5,129 immigrant children in the United States. On June 3, 2018, Oregon Senator Jeff Merkley was denied entrance to the Casa Padre facility as part of his investigation into the living conditions of the children. The recorded exchange between Merkley and the empl

Receptor-type tyrosine-protein phosphatase H is an enzyme that in humans is encoded by the PTPRH gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. The extracellular region contains eight fibronectin type III-like repeats and multiple N-glycosylation sites. The gene was shown to be expressed primarily in brain and liver, and at a lower level in heart and stomach. It was also found to be expressed in several cancer cell lines, but not in the corresponding normal tissues.

Gregory Shantha Kumar Francis (B.Th., PGDip.P&CC), was an Anglican Bishop of Kurunegala, Sri Lanka. Gregory Shantha Kumar Francis was born in 1955 in the village of Polgahawela, Sri Lanka. He is an upcountry Tamil, and fluent in Sinhala, English and Tamil. On 7 November 2010 Rowan Williams, Archbishop of Canterbury, appointed Francis as the fifth Bishop of Kurunegala in the Church of Ceylon, succeeding retired Bishop Kumara Illangasinghe. In 2012, Francis was nominated by the International Counter Narcotic Association to be a consultant on rehabilitation and counselling.

Nicalin is a protein that in humans is encoded by the NCLN gene.

Club Atlético Aldosivi (usually called simply Aldosivi) is an Argentine football club based in the city of Mar del Plata. The institution was founded on March 29, 1913, and plays in the Argentine Primera División. The club's name comes from the first two letters of the last name of their founders, Allard, Doulfus, Sillard, and Wiriott (the "w" was changed to a "v" because there was no "W" available to telegraph the official announcement). In 1979, Aldosivi merged with two other clubs from Mar del Plata, Talleres and Banfield, and was known by the name Defensores del Puerto until 1981 when it returned to the traditional name, which it still uses today.

Strength of a Woman is the thirteenth studio album by American singer Mary J. Blige. It was released on April 28, 2017 by Capitol Records. The album features Guests appearances by Quavo, DJ Khaled, Missy Elliott, Prince Charlez, and Kaytranada.

Oscar Erik Anders Klefbom (born 20 July 1993) is a Swedish professional ice hockey defenceman currently playing for the Edmonton Oilers of the National Hockey League (NHL). He was selected 19th overall in the 2011 NHL Entry Draft by the Oilers.

DXDE-TV channel 29, is a television station owned by Golden Broadcasting Professionals, Inc.. and currently is the affiliated station of the Philippine television network 5 Plus. The station is operated and co-owned by TV5 Network Inc.. Its studios and transmitter are located at GBPI Building, Campaner Street, Zamboanga City. Currently, 5 Plus Channel 29 Zamboanga is inactive on analog, because they have switched to digital TV by eMedia.

General elections were held in Bosnia and Herzegovina on 7 October 2018. Voters elected the national Presidency and House of Representatives, as well as the Presidents and legislatures of the two entities and the legislatures of the ten cantons of the federation of Bosnia and Herzegovina

E3 ubiquitin-protein ligase Praja1 is an enzyme that in humans is encoded by the PJA1 gene.

Interleukin-2 receptor alpha chain (also called CD25) is a protein that in humans is encoded by the IL2RA gene. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolysis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is currently unknown.

Kingston Town (31 August 1976 – March 1991) was an outstanding Australian bred Thoroughbred racehorse who once held a record three Cox Plates and 11 other Group One races in a career spanning from 1979 to 1982. In 1980 he was awarded the honour of being the Australian Champion Racehorse of the Year.

Michaela Blyde (born 29 December 1995) is a New Zealand rugby sevens player. Blyde debuted for New Zealand as a 17 year-old in the 2013 Oceania Women's Sevens Championship. She was the top try scorer of the 2016-17 World Rugby Women's Sevens Series, and was named 2017 World Rugby Women's Sevens Player of the Year.In 2018, Blyde was named World Rugby Women's Sevens Player of the Year for the second year running.

Ubiquitin carboxyl-terminal hydrolase 40 is an enzyme that in humans is encoded by the USP40 gene.

DNA-directed RNA polymerase III subunit RPC5 is an enzyme that in humans is encoded by the POLR3E gene.

Peroxisomal proliferator-activated receptor A interacting complex 285, also known as PRIC285, is a human gene. The protein encoded by this gene is a nuclear transcriptional co-activator for peroxisome proliferator activated receptor alpha. The encoded protein contains a zinc finger and is a helicase that appears to be part of the peroxisome proliferator activated receptor alpha interacting complex. This gene is a member of the DNA2/NAM7 helicase gene family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Microsomal prostaglandin E synthase-1 (mPGES-1) or Prostaglandin E synthase is an enzyme that in humans is encoded by the PTGES gene. The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53-induced apoptosis.

Oxysterol-binding protein-related protein 2 is a protein that in humans is encoded by the OSBPL2 gene. This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.

Basic salivary proline-rich protein 3 is a protein that in humans is encoded by the PRB3 gene. The protein encoded by this gene is a proline-rich salivary protein. It is a major constituent of parotid saliva. This protein is proposed to act as a bacterial receptor. This gene and five other genes that also encode salivary proline-rich proteins (PRPs), as well as a gene encoding a lacrimal gland PRP, form a PRP gene cluster in the chromosomal 12p13 region.

Peter Seitz (born 1931) is a graphic designer, author, teacher and business owner who served as the first Design Director at The Walker Art Center (Minneapolis, MN), and helped establish the graphic design program at the Minneapolis College of Art and Design.

Tensin-4 is a protein that in humans is encoded by the TNS4 gene.

This article summarizes the highlights of professional and amateur golf in the year 2006.

Protein LMBR1L is a protein that in humans is encoded by the LMBR1L gene.

‹ The template Infobox gene is being considered for merging. › KANSL3, or KAT8 regulatory NSL complex subunit 3 is a protein that in humans is encoded by the KANSL3 gene.

La Cenicienta (Cinderella) is an opera in three acts composed by Chilean artist Jorge Peña Hen (1928–1973), to a libretto by the Chilean author, (1910–1988). This opera is one of the few operas in the world composed with the aim to be sung, acted and played exclusively by children. It was written in 1966 and played by Jorge Peña Hen's first at the Theater of the Girls Public School in La Serena, a city in the northern region of Coquimbo. In 1967, a production of La Cenicienta went on a tour through several cities in Chile: Valparaíso, Viña del Mar, Concepción and Santiago, the capital. Its debut was considered a great success. In 1986, a new version of this children's opera was played in Colombia. In 1998, 25 years after Jorge Peña Hen's assassination by Chile's military coup officials, another version was re-made in La Serena. In 2004, a new staging by , and in 2005 by University of Chile's Theatre in Santiago, Chile. The plot of the opera is based on Charles Perrault's classic fairy tale Cinderella.

Semaphorin-6C is a protein that in humans is encoded by the SEMA6C gene. This gene product is a member of the semaphoring family of proteins. Semaphorins represent important molecular signals controlling multiple aspects of the cellular response that follows CNS injury, and thus may play an important role in neural regeneration.

Ryan Keith Zinke (; born November 1, 1961) is an American politician and businessman who served as United States Secretary of the Interior in the Trump Administration from 2017 until his resignation in 2019. He previously served as the U.S. Representative for Montana's at-large congressional district from 2015 to 2017. From 2009 to 2013, he served as a member of the Montana Senate, representing the 2nd district. Zinke played college football at the University of Oregon and earned a Bachelor of Science degree in geology. He also has a Master of Business Administration and a Master of Science in global leadership. He was a U.S. Navy SEAL from 1986 until 2008, retiring with the rank of commander. The first Navy SEAL to be elected to the United States House of Representatives, Zinke formerly served as a member on the Natural Resources Committee and the Armed Services Committee. As a member of Congress, Zinke supported the use of ground troops in the Middle East to combat ISIS and opposed the Affordable Care Act, various environmental regulations, and the transfer of federal lands to individual states. Zinke was appointed as United States Secretary of the Interior by President Donald Trump. Zinke was confirmed on March 1, 2017, becoming the first Navy SEAL and the first Montanan since statehood to occupy a Cabinet position. As Secretary, Zinke opened more federal lands for oil, gas and mineral exploration and extraction. Zinke's expenditures as Secretary of the Interior, which included expensive flights, raised ethical questions and controversy, and were investigated by the Interior Department's Office of Inspector General. His ethical troubles were the subject of a PBS News Hour report on October 19, 2018. On October 30, 2018, the investigation into Zinke was referred to the Justice Department by Interior's Inspector General. Trump announced on December 15, 2018, that Zinke would leave his post on January 2, 2019, to be replaced by his deputy David Bernhardt.

Sujanagar (Bengali: সুজানগর) is an Upazila of Pabna District in the Division of Rajshahi, Bangladesh. The upazila is the home of agriculture across the district. Kashinathpur bazar and Nagarbari is the famous place in sujanagar which is basically commercial capital of the Upazila.

VIPAS39, formerly known as C14orf133, is a protein that in humans is encoded by the VIPAS39 gene. This protein is involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2 (arthrogryposis, renal dysfunction, and cholestasis-2). Alternative splicing results in multiple transcript variants.

Microsomal prostaglandin E synthase-1 (mPGES-1) or Prostaglandin E synthase is an enzyme that in humans is encoded by the PTGES gene. The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53-induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.

Lene Cecilia Sparrok (born 6 October 1997) is a Norwegian Southern Sámi actress. She was the star of the Swedish 2016 film Sami Blood. Sporrok was born in Namsskogan, Nord-Trøndelag. Outside of acting, she is a professional reindeer herder.

Tetratricopeptide repeat protein 35 is a protein that in humans is encoded by the TTC35 gene.

Myeloid-associated differentiation marker is a protein that in humans is encoded by the MYADM gene.

Bryan Pamba (born January 7, 1992 in Paris, France) is a French basketball player who plays for French Pro A league club Orleans.

Vacuolar protein sorting-associated protein 52 homolog is a protein that in humans is encoded by the VPS52 gene. This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18.

José María Callejón Bueno (Spanish pronunciation: [xoˈse kaʎeˈxon]; born 11 February 1987) is a Spanish professional footballer who plays for Italian club S.S.C. Napoli as a forward or winger. He began his career with the reserve teams of Real Madrid, but made a name for himself at Espanyol. In 2011 he returned to his previous club and, two years later, left for Napoli. A under-21 international, Callejón made his senior debut for Spain in 2014.

SLC35F6 is a protein that in humans is encoded by the SLC35F6 gene. The orthologue in mice is 4930471M23Rik.

Ras-related protein Rab-33A is a protein that in humans is encoded by the RAB33A gene. The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is GTP-binding protein and may be involved in vesicle transport.

Oxford Blue is the official colour of the University of Oxford. The official Oxford branding guidelines set the definition of Oxford Blue as Pantone 282, equivalent to the hex code #002147. With a hue code of 212, this colour is a very dark tone of azure. Azure colours are those colours with a hue code of between 195 and 225.

Sentrin-specific protease 7 is an enzyme that in humans is encoded by the SENP7 gene.

This article summarizes the events, album releases, and album release dates in hip hop music for the year 2006.

706 Hirundo is a minor planet orbiting the Sun.

Splicing factor, arginine/serine-rich 11 is a protein that in humans is encoded by the SFRS11 gene. This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing.

Nina Boucicault (27 February 1867 – 2 August 1950) was an English actress born to playwright Dion Boucicault and his wife, actress Agnes Kelly Robertson. She had three brothers, Dion William (1855–1876), Dion Boucicault Jr. and Aubrey Boucicault, and two sisters, Eva and Patrice. Her debut was at the Louisville Opera House and as a child she performed with her father. Beginning in 1892, she played Kitty Verdun in the original production of the hit comedy Charley's Aunt. She was the first to play the title role in J. M. Barrie's Peter Pan, beginning in 1904 at the Duke of York's Theatre.

Michael Nestor is an American musician. He is the lead singer of Underlined Passages, and the founder of The Beechfields Record Label.

T-cell receptor-associated transmembrane adapter 1 is a protein that in humans is encoded by the TRAT1 gene.

Sialic acid synthase is an enzyme that in humans is encoded by the NANS gene. This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively. However, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.

Paper is a thin unwoven material made from milled plant fibers, is primarily used for writing, artwork, and packaging; it is commonly white. The first papermaking process was documented in China during the Eastern Han period (25–220 CE), traditionally attributed to the court official Cai Lun. Officially paper was invented by the Ancient Chinese. Papyrus is different and was invented by Egyptians. During the 8th century, Chinese papermaking spread to the Islamic world, where pulp mills and paper mills were used for papermaking and money making. By the 11th century, papermaking was brought to Europe. By the 13th century, papermaking was refined with paper mills utilizing waterwheels in Spain. Later European improvements to the papermaking process came in the 19th century with the invention o

Mitochondrial import inner membrane translocase subunit Tim23 is an enzyme that in humans is encoded by the TIMM23 gene.

39S ribosomal protein L4, mitochondrial is a protein that in humans is encoded by the MRPL4 gene. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified alternatively spliced variants that encode different protein isoforms.

Neurexophilin-3 is a protein that in humans is encoded by the NXPH3 gene.

Mark Batson (born September 9, 1968) is an American producer, musician and songwriter. He has worked on albums by artists including Alicia Keys, Leann Rimes, Jay Z, Dave Matthews Band, Beyoncé, Maroon 5, Dr. Dre, Eminem, 50 Cent, James Blunt, Anthony Hamilton, Skylar Grey, Grace Potter and the Nocturnals, Seal, Nas, and Sting.

Zinc finger protein 44 is a protein that in humans is encoded by the gene.

Robert Forbes Hawkes (August 25, 1865 – August 24, 1940) was an American physician and surgeon who was prominent in New York society during the Gilded Age.

Acoustical Intelligence (ACOUSTINT, sometimes ACINT) is an intelligence gathering discipline that collects and processes acoustic phenomena. It is a subdiscipline of MASINT (Measurement and Signature Intelligence). This uses broadband and narrowband analysis of acquired acoustic signatures from surface ships and submarines, although it can also be used for low-flying aircraft such as helicopters. Broadband analysis concerns the overall noise created by a platform, whereas narrowband analysis examines the spectra of the received energy at a more precise level. Broadband analysis is useful for identifying any vessel at a long range, whereas narrowband analysis is generally more useful for identifying the category, type and ideally the individual vessel name. The category might be for example differentiating between a commercial vessel and a warship; the type might be narrowing this down to an individual class and hence identifying nationality, and the individual name might identify the specific ship or submarine. As a simple example, narrowband analysis might identify whether a subject of interest has single or multiple propeller shafts; how many blades per shaft and other salients that may help identify the platform. This may include the fundamental or harmonic emissions based on the electric services used, the gearing between shaft and engine and also the combination of gear teeth used in the ratio(s). For nuclear vessels, necessary pump frequencies can be detected. It is possible for an expert to work out how many gears, teeth and ratios are used from engine right through to propeller; this can be used to identify a particular type. Sometimes, there are machining faults - however small - introduced at the manufacturing stage. This can help to identify individual platforms.

Protocadherin alpha-5 is a protein that in humans is encoded by the PCDHA5 gene. This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Replication termination factor 2 is a protein that in humans is encoded by the RTF2 gene.

Immunoglobulin superfamily, member 2 (IGSF2) also known as CD101 (Cluster of Differentiation 101), is a human gene.

Signal-regulatory protein gamma is a protein that in humans is encoded by the SIRPG gene. SIRPG has also recently been designated CD172G (cluster of differentiation 172G). The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described.

Myosin regulatory light chain 12A is a protein that in humans is encoded by the MYL12A gene.

A fermata (Italian: [ferˈmaːta]; "from fermare, to stay, or stop"; also known as a hold, pause, colloquially a birdseye or cyclops eye, or as a grand pause when placed on a note or a rest) is a symbol of musical notation indicating that the note should be prolonged beyond the normal duration its note value would indicate. Exactly how much longer it is held is up to the discretion of the performer or conductor, but twice as long is common. It is usually printed above but can be occasionally below (when it is upside down) the note to be extended.

Calcineurin subunit B type 2 is a protein that in humans is encoded by the PPP3R2 gene. Among its related pathways are MAPK signaling pathway and . GO annotations related to this gene include calcium ion binding. An important paralog of this gene is .

The subfamily Poiocerinae include Hemipteran insects in the family Fulgoridae, found especially in the tropics.

Henry Farrell (September 27, 1920 – March 29, 2006) was an American novelist and screenwriter, best known as the author of the renowned gothic horror story What Ever Happened to Baby Jane?, which was made into a film starring Bette Davis and Joan Crawford.

Stand By Your Man is an American sitcom that aired on Fox from April 5, 1992 to May 17, 1992. The series was created by Nancy Steen and Neil Thompson, who also wrote some of the episodes. It is notable for being Melissa Gilbert's return to series television after the conclusion of Little House on the Prairie nine years earlier, and the first lead sitcom role for Rosie O'Donnell, who was then on the verge of breaking into major fame. The series was created as an American adaptation of the British sitcom Birds of a Feather, which was still in production at the time.

SH3 and PX domain-containing protein 2A is a protein that in humans is encoded by the SH3PXD2A gene.

Transmembrane BAX inhibitor motif-containing protein 1 is a protein that in humans is encoded by the TMBIM1 gene.

Protein pellino homolog 1 is a protein that in humans is encoded by the PELI1 gene.

Ribonucleoside-diphosphate reductase large subunit is an enzyme that in humans is encoded by the RRM1 gene. This gene encodes one of two non-identical subunits which constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. This gene is oriented in a head-to-tail configuration with the stromal interaction molecule 1 gene (STIM1), with the 3' end of STIM1 situated 1.6 kb from the 5' end of this gene.

Alfredo Carlos Arias Sánchez (born November 28, 1958 in Shangrilá, Uruguay) is a Uruguayan football manager and former footballer who played for different clubs in Uruguay, Chile and Mexico. He currently manages Club Universidad de Chile in Chile.

Ribonucleoside-diphosphate reductase large subunit is an enzyme that in humans is encoded by the RRM1 gene. This gene encodes one of two non-identical subunits which constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. This gene is oriented in a head-to-tail configuration with the stromal interaction molecu

RNA-binding protein 28 is a protein that in humans is encoded by the RBM28 gene.

Rex1 (Zfp-42) is a known marker of pluripotency, and is usually found in undifferentiated embryonic stem cells. In addition to being a marker for pluripotency, its regulation is also critical in maintaining a pluripotent state. As the cells begin to differentiate, Rex1 is severely and abruptly downregulated.

The Music Machine was an American rock band formed in Los Angeles, California in 1966. Fronted by chief songwriter and lead vocalist Sean Bonniwell, the band cultivated a characteristically dark and rebellious image reflected in an untamed musical approach. Sometimes it made use of distorted guitar lines and hallucinogenic organ parts, punctuated by Bonniwell's distinctively throaty vocals. Although they managed to attain national chart success only briefly with two singles, the Music Machine is today considered by many critics to be one of the groundbreaking acts of the 1960s. Their style is now recognized as a pioneering force in proto-punk; yet within a relatively short period of time, they began to employ more complex lyrical and instrumental arrangements that went beyond the typical g

28S ribosomal protein S17, mitochondrial is a protein that in humans is encoded by the MRPS17 gene. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs

Dichoptera is a genus of plant-hoppers found in tropical Asia. They were formerly placed in the family Dictyopharidae. They have large and stout bodies with long membranous forewings. The head is short and may have a long process. There are 11 species in the genus. Often found on the bark of Ficus trees, they are tended by ants and sometimes parasitized by Dryinidae.

Casa Padre is a shelter for unaccompanied or separated immigrant minors in custody of the U.S. Office of Refugee Resettlement, a division of Health & Human Services, located in Brownsville, Texas . The building was formerly a Walmart store. The center is run by the nonprofit group Southwest Key Programs under contract from the federal government. Casa Padre is the largest licensed childcare facility in the United States, housing approximately 1,500 youths. According to the Internal Revenue Service, the group houses approximately 5,129 immigrant children in the United States. On June 3, 2018, Oregon Senator Jeff Merkley was denied entrance to the Casa Padre facility as part of his investigation into the living conditions of the children. The recorded exchange between Merkley and the employees of the facility was uploaded to YouTube and was shared 1.1 million times.

Xanxerê is a city in Santa Catarina, southern Brazil. Italian and German are the mainstream cultures, having been brought by immigrants in the early 20th century through the migration of the "gauchos". The city is one of the main production centers of corn in Brazil and serves as an important industrial, commercial and service center for western Santa Catarina. It is located in a key position for trades via Mercosul. Xanxerê is the headquarters of the Association of Cities of Alto Irani (AMAI), composed of 17 "municípios". On April 20, 2015, two tornadoes struck the city; two people died and another 120 were injured, according to the news. These tornadoes was most likely an F3 on the Fujita Scale, according to Mamedes Luiz Melo, a INMET meteorologist. At least 2,600 homes were damaged.

THO complex subunit 2 is a protein that in humans is encoded by the THOC2 gene. THO2 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), HPR1 (MIM 606930), ALY (MIM 604171), and UAP56 (MIM 606390).[supplied by OMIM]

Retinoic acid receptor responder protein 1 is a protein that in humans is encoded by the RARRES1 gene. This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.

Chris Gittins (4 July 1902 – 20 August 1988) was a British character actor who played the role of Walter Gabriel in the long-running BBC radio series The Archers. Gittins was born in Stourbridge, Worcestershire. His first radio part was on 13 November 1935. He played the role of Walter Gabriel, a tenant farmer, in The Archers for 35 years from 1953 to 1988, and was known nationally for the character's phrase "My old pal, my old beauty". He also appeared in several TV series including Hilda Lessways (1959) and Swizzlewick (1964).

ADP-sugar pyrophosphatase is an enzyme that in humans is encoded by the NUDT5 gene. Nudix hydrolases, such as NUDT5, eliminate toxic nucleotide derivatives from the cell and regulate the levels of important signaling nucleotides and their metabolites (McLennan, 1999).[supplied by OMIM]

Protocadherin alpha-5 is a protein that in humans is encoded by the PCDHA5 gene. This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasm

John Wick: Chapter 3 – Parabellum is an upcoming American neo-noir action thriller film starring Keanu Reeves as the titular character in the third installment in the John Wick film series, following John Wick (2014) and John Wick: Chapter 2 (2017). The film is directed by Chad Stahelski and written by Derek Kolstad, Shay Hatten, Chris Collins and Marc Abrams, based on a story by Kolstad. It also stars Halle Berry, Laurence Fishburne, Mark Dacascos, Asia Kate Dillon, Lance Reddick, Anjelica Huston and Ian McShane. The first film was always intended to begin a franchise, and a third installment was announced in June 2017. Much of the returning cast and crew was confirmed in February 2018, with new members joining that May. Filming began that month and lasted through November, taking place in New York City, Montreal, Russia, Morocco and Spain. The film is scheduled to be theatrically released in the United States on May 17, 2019, by Lionsgate.

Neurotrimin is a protein that in humans is encoded by the NTM gene. This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML) on chromosome 11. Multiple alternatively spliced variants have been found but only two variants have had their full-length sequences determined.

Putative methyltransferase NSUN5 is an enzyme that in humans is encoded by the NSUN5 gene. This gene encodes a protein with similarity to p120 (NOL1), a 120-kDa proliferation-associated nucleolar antigen that is a member of an evolutionarily conserved protein family. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

The Lost Provinces were relatively inaccessible regions of North Carolina in the 19th and early 20th centuries, under-served by roads and railroads. In the mountainous northwest corner of the state, west of the Eastern Continental Divide. Ashe, Alleghany and Watauga counties in the New River basin were cut off from the rest of the state by the high Blue Ridge Mountains. The area's mountainous topography caused these counties to be most closely connected to Smyth and Grayson counties in Virginia, and to Johnson and Carter counties in Tennessee. The first highway to connect the area to points east was the Blowing Rock Turnpike. Started in 1911, it ran to Lenoir in Caldwell County. In 1914 a railroad was built to connect Ashe County to Abingdon, Virginia. After 1921 North Carolina Highway 16 connected Ashe County to Wilkesboro. Other references to "lost provinces" of North Carolina have been applied to eastern counties north of the Albemarle Sound that had historically related more closely to Virginia than to the rest of the state.

Tetraspanin-3 is a protein that in humans is encoded by the TSPAN3 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Two alternative transcripts encoding different isoforms have been described.

The 2009 Tampa Bay Buccaneers season was the franchise's 34th season in the National Football League the 12th playing their home games at Raymond James Stadium, and the first under head coach Raheem Morris. The Buccaneers looked to improve on their 9–7 record from their 2008 season and 3rd-place finish in the NFC South but failed to do so as they finished the season at 3–13, missing the playoffs for the second straight year.

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.

Phosphoribosyl pyrophosphate synthetase-associated protein 1 is an enzyme that in humans is encoded by the PRPSAP1 gene.

SLC2A4 regulator is a protein that in humans is encoded by the SLC2A4RG gene. The protein encoded by this gene is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. The encoded protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene.

Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (PP2BC) is an enzyme that in humans is encoded by the PPP3CC gene. Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha (CALNA1; MIM 114105), calcineurin A-beta (CALNA2; MIM 114106), and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).[supplied by OMIM]

Matthew Brett Cardona (born May 14, 1985) is an American professional wrestler. He is currently signed to WWE, where he performs on the Raw brand under the ring name Zack Ryder where he is one half of the Raw Tag Team Champions with Curt Hawkins. After joining WWE, he has since become a one-time Intercontinental Champion, a one-time United States Champion and a one-time WWE Tag Team Champion.

Probable ribosome biogenesis protein RLP24 is a protein that in humans is encoded by the RSL24D1 gene. This gene encodes a protein sharing a low level of sequence similarity with human ribosomal protein L24. Although this gene has been referred to as RPL24, L30, and 60S ribosomal protein L30 isolog in the sequence databases, it is distinct from the human genes officially named RPL24 (which itself has been referred to as ribosomal protein L30) and RPL30. The function of this gene is currently unknown. This gene utilizes alternative polyadenylation signals.

Xanxerê is a city in Santa Catarina, southern Brazil. Italian and German are the mainstream cultures, having been brought by immigrants in the early 20th century through the migration of the "gauchos". The city is one of the main production centers of corn in Brazil and serves as an important industrial, commercial and service center for western Santa Catarina. It is located in a key position for trades via Mercosul. Xanxerê is the headquarters of the Association of Cities of Alto Irani (AMAI), composed of 17 "municípios".

The 2008 Tampa Bay Buccaneers season was the franchise's 33rd season in the National Football League the 11th playing their home games at Raymond James Stadium, and the seventh and final under head coach Jon Gruden. Though the team finished with a winning record (9–7), they failed to defend their 2007 NFC South championship and did not qualify for the playoffs for the first time since 2006, after finishing the year on a four-game losing streak. Just weeks after the conclusion of the regular season, head coach Jon Gruden was fired,a move that came as a surprise both to sports writers and Gruden himself. General manager Bruce Allen was also fired.

Harris Corner Detector is a corner detection operator that is commonly used in computer vision algorithms to extract corners and infer features of an image. It was first introduced by Chris Harris and Mike Stephens in 1988 upon the improvement of Moravec's corner detector. Compared to the previous one, Harris' corner detector takes the differential of the corner score into account with reference to direction directly, instead of using shifting patches for every 45 degree angles, and has been proved to be more accurate in distinguishing between edges and corners. Since then, it has been improved and adopted in many algorithms to preprocess images for subsequent applications.

Tobitakyū Station (飛田給駅 Tobitakyū-eki) is a railway station in Chōfu, Tokyo, Japan, operated by the private railway operator Keio Corporation. It serves as the main train station for access to Ajinomoto Stadium, home of J. League football teams F.C. Tokyo and Tokyo Verdy.

Lipoma HMGIC fusion partner is a protein that in humans is encoded by the LHFP gene. This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. This gene is fused to a high-mobility group gene in a translocation-associated lipoma. Mutations in another LHFP-like gene (LHFPL1, LHFPL2) result in deafness in humans and mice. Alternatively spliced transcript variants have been found; however, their full-length nature is not known.

tRNA wybutosine-synthesizing protein 2 homolog is a protein that in humans is encoded by the TRMT12 gene.

Dulcify (1975–1979) was a New Zealand-bred Thoroughbred racehorse. His British-bred sire was the 1970 Irish 2,000 Guineas winner, Decies, a grandson of Pharis, the very important French sire whom Thoroughbred Heritage says is considered one of the greatest French-bred runners of the century. Dulcify's dam was the Australian mare Sweet Candy, a daughter of 1957 Golden Slipper Stakes winner and Australian Racing Hall of Fame inducteeTodman. Dulcify was owned and raced by Colin Hayes, who purchased him for $3,250. Hayes called him the best horse he ever raced. Dulcify was a patient, come-from-behind runner. His most important career win came in the 1979 Cox Plate, which he won by a still-standing record of seven lengths.The betting favourite for the 1979 Melbourne Cup, he suffered a broken pelvis during the race and had to be euthanized. Inducted into the Australian racing Hall of Fame in 2014

Ghislaine Landry (born April 27, 1988) is a Canadian rugby union player. She won a gold medal at the 2015 Pan American Games as a member of the Canadian women's rugby sevens team. As of the 2016-17 season, Landry succeeded Jen Kish as captain of the national sevens. On 20 October 2018, Landry became the first woman to hit the 1,000 point milestone in the women's sevens World Series. Landry attended Saint Francis Xavier University.

Ryan Keith Zinke (; born November 1, 1961) is an American politician and businessman who served as United States Secretary of the Interior in the Trump Administration from 2017 until his resignation in 2019. He previously served as the U.S. Representative for Montana's at-large congressional district from 2015 to 2017. From 2009 to 2013, he served as a member of the Montana Senate, representing the 2nd district.

28S ribosomal protein S16, mitochondrial is a protein that in humans is encoded by the MRPS16 gene. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs

Ubiquitin-conjugating enzyme E2 O is a protein that in humans is encoded by the UBE2O gene. UBE2O functions during terminal erythroid differentiation to eliminate generic cellular components in parallel with abundant synthesis of hemoglobin.

Methionine-R-sulfoxide reductase B1 is an enzyme that in humans is encoded by the SEPX1 gene. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein belongs to the methionine sulfoxide reductase B (MsrB) family, and it is expressed in a variety of adult and fetal tissues.

The 10.30 Slot was a music and variety show that aired on ABC TV on Friday nights between 1999 and 2000, which was hosted by Dylan Lewis and Angus Sampson. It was similar in format to Lewis and Sampson's previous show, Recovery, although The 10.30 Slot's late-night timeslot allowed for more adult-oriented content, compared to Recovery's youth-based focus. Ironically the program often did not start at 10:30pm as the title would suggest, but the time of its airing was contingent on the late edition of ABC News and other ABC broadcasting priorities on a particular Friday night. After the series ended Lewis presented Pepsi Live from 2001. Sampson was later a performer and series winner on the improvised comedy show, Thank God You're Here.

The 2018 Advance Auto Parts Clash was a Monster Energy NASCAR Cup Series race held on February 11, 2018, at Daytona International Speedway in Daytona Beach, Florida. Contested over 75 laps, it was the first exhibition race of the 2018 Monster Energy NASCAR Cup Series season.

Charles J. Moore is an oceanographer and boat captain known for articles that recently brought attention to the 'Great Pacific Garbage Patch', an area of the Pacific Ocean strewn with floating plastic debris which is three times the size of Texas.

Thomas Wentworth Wills (19 August 1835 – 2 May 1880) was a sportsman who is credited with being Australia's first cricketer of significance and a founder of Australian rules football. Born in the British colony of New South Wales to a wealthy family descended from convicts, Wills grew up in the bush on properties owned by his father, the pastoralist and politician Horatio Wills, in what is now the Australian state of Victoria. He befriended local Aborigines, learning their language and customs. At the age of 14, Wills went to England to attend Rugby School, where he became captain of its cricket team, and played an early version of rugby football. After Rugby, Wills represented the Cambridge University Cricket Club in the annual match against Oxford, and played at first-class level for Kent and the Marylebone Cricket Club. An athletic all-rounder with exceptional bowling skills, he was regarded as one of the finest young cricketers in England. Returning to Victoria in 1856, Wills achieved Australia-wide stardom as a cricketer, captaining the Victorian team to repeated victories in intercolonial matches. He played for, but often came to blows with the Melbourne Cricket Club, his larrikin streak and defections to rival clubs straining their relationship. In 1858 he called for the formation of a "foot-ball club" with a "code of laws" to keep cricketers fit during winter. After founding the Melbourne Football Club in 1859, Wills co-wrote the first laws of Australian rules football. He and his cousin H. C. A. Harrison spearheaded the sport's development as captains, umpires and administrators. In 1861, at the height of his fame, Wills joined his father on an eight-month trek into the Queensland outback to found a new property. Soon after their arrival, Wills' father and 18 others perished in the deadliest massacre of settlers by Aborigines in Australian history. Wills survived and resumed playing sport upon his return to Victoria in 1864, and in 1866–67, led an Aboriginal cricket team on an Australian tour as its captain-coach. In a career marked by controversy, Wills challenged cricket's amateur-professional divide, and developed a reputation for bending sporting rules to the point of cheating. In 1872, he became the first bowler to be called for throwing in a top-class Australian match. Dropped from the Victoria XI, he failed in an 1876 comeback attempt, by which time he was considered a relic of a bygone era. His remaining years were characterised by social alienation, flights from creditors, and heavy drinking, likely as a means of coping with posttraumatic stress disorder (PTSD) symptoms that plagued him after the massacre. In 1880, suffering from delirium tremens, Wills committed suicide by stabbing himself in the heart. Australia's first sporting celebrity, Wills fell into obscurity after his death, but has undergone a revival in Australian culture since the 1980s. Today he is described as an archetypal tragic sports hero and as a symbol of reconciliation between Indigenous and non-Indigenous Australians. He has also become the central figure in "football's history wars"—an ongoing dispute over whether features of an Aboriginal game were incorporated into early Australian rules football. According to biographer Greg de Moore, Wills "stands alone in all his absurdity, his cracked egalitarian heroism and his fatal self-destructiveness—the finest cricketer and footballer of the age".

Club Atlético Aldosivi (usually called simply Aldosivi) is an Argentine football club based in the city of Mar del Plata. The institution was founded on March 29, 1913, and plays in the Argentine Primera División. The club's name comes from the first two letters of the last name of their founders, Allard, Doulfus, Sillard, and Wiriott (the "w" was changed to a "v" because there was no "W" available to telegraph the official announcement).

This is a list of murdered political dissidents and human rights activists. The list is chronological.

Wrongful execution is a miscarriage of justice occurring when an innocent person is put to death by capital punishment. Cases of wrongful execution are cited as an argument by opponents of capital punishment, while proponents suggest that the argument of innocence concerns the credibility of the justice system as a whole and does not solely undermine the use of death penalty. A number of people are claimed to have been innocent victims of the death penalty. Newly available DNA evidence has allowed the exoneration and release of more than 20 death row inmates since 1992 in the United States, but DNA evidence is available in only a fraction of capital cases. Others have been released on the basis of weak cases against them, sometimes involving prosecutorial misconduct; resulting in acquittal at retrial, charges dropped, or innocence-based pardons. The Death Penalty Information Center (U.S.) has published a list of 10 inmates "executed but possibly innocent". Of all executions in the United States, 144 prisoners have been exonerated while on death row. In the UK, reviews prompted by the Criminal Cases Review Commission have resulted in one pardon and three exonerations for people executed between 1950 and 1953 (when the execution rate in England and Wales averaged 17 per year), with compensation being paid.

Protein phosphatase 1F is an enzyme that in humans is encoded by the PPM1F gene. The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length

Mobb Deep was an American hip hop duo from Queensbridge, Queens, New York. The group consisted of Havoc and Prodigy, and were a hardcore East Coast hip hop group. They were known for their dark, hardcore delivery as exemplified in "Shook Ones (Part II)." Mobb Deep became one of the most successful rap duos in hip hop, having sold over 3 million records. Three of their notable albums were The Infamous (1995), Hell On Earth (1996) and Murda Muzik (1999), and their top hits include "Shook Ones, Pt. II", "Survival of the Fittest" and "Hell on Earth". The duo disbanded in 2012 but reunited in 2013. Prodigy died on June 20, 2017.

Dr H.A. Hellyer , a British scholar and analyst, writes on the politics of the modern Arab world, religion and politics in Europe and internationally, majority-minority relations, security issues and the Muslim world - West relations. He is a senior nonresident fellow at the Atlantic Council's Center for the Middle East, and associate fellow at the Royal United Services Institute. Previously a nonresident fellow at the Brookings Institution's Foreign Policy section, and he was also Democracy Non-Resident Fellow for the academic year 2014 - 2015 at the John F. Kennedy School of Government of Harvard University. Dr Hellyer was previously Senior Practice Consultant at the Abu Dhabi Gallup Center, and Senior Research Fellow at the University of Warwick. Dr Hellyer was appointed to the British government's Taskforce on Tackling Radicalisation and Extremism. Dr. Hellyer was appointed as deputy convener of the United Kingdom taskforce on tackling radicalization and extremism after the 7/7 bombings in London in 2005. He also served as the U.K. Foreign and Commonwealth Office’s (FCO) first economic and social research council fellow, within its Islam team and counter-terrorism team. He is the author of a number of books and articles, including "Muslims of Europe: the 'Other' Europeans" published by Edinburgh University Press, and "A Revolution Undone: Egypt's Road beyond Revolt" published and distributed by Hurst and Company & Oxford University Press.

John Wick: Chapter 3 – Parabellum is an upcoming American neo-noir action thriller film starring Keanu Reeves as the titular character in the third installment in the John Wick film series, following John Wick (2014) and John Wick: Chapter 2 (2017). The film is directed by Chad Stahelski and written by Derek Kolstad, Shay Hatten, Chris Collins and Marc Abrams, based on a story by Kolstad. It also stars Halle Berry, Laurence Fishburne, Mark Dacascos, Asia Kate Dillon, Lance Reddick, Anjelica Huston and Ian McShane.

Protocadherin beta-9 is a protein that in humans is encoded by the PCDHB9 gene. This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Heavy is a 1995 American drama film written and directed by James Mangold, and starring Liv Tyler, Pruitt Taylor Vince, Shelley Winters, and Deborah Harry. The plot focuses on an unhappy overweight cook (Vince) whose life is changed after an enchanting college drop-out (Tyler) begins working as a waitress at his and his mother's roadside tavern. The film explores themes of loneliness, false hope, unrequited love, and self-worth. The film was Mangold's directorial debut, and he wrote the screenplay for it while attending filmmaking seminars at Columbia University. The film features an original soundtrack by Thurston Moore, as well as songs by Evan Dando of The Lemonheads, who also had a minor role in the film. Filming took place on location in and around Barryville and Hyde Park, New York; some scenes were filmed at the Culinary Institute of America's campus there. Heavy premiered at the Sundance Film Festival where it won the Special Jury Prize and was later screened at Cannes before receiving major theatrical releases. It was first released in the United Kingdom on December 29, 1995, and later received a limited release in the United States on June 5, 1996. It has since had several home video releases, including two DVD releases which are both currently out of production.

Shea Michael Weber (born August 14, 1985) is a Canadian professional ice hockey defenceman who currently serves as the captain for the Montreal Canadiens of the National Hockey League (NHL). He is an NHL All-Star and a two-time Olympic gold medalist. Drafted in the second round, 49th overall, by the Nashville Predators in the 2003 NHL Entry Draft, Weber had spent his entire NHL career with the Predators until being traded to Montreal. He had previously played for the Sicamous Eagles of the Kootenay International Junior Hockey League (KIJHL), the Kelowna Rockets of the Western Hockey League (WHL) and the Milwaukee Admirals of the American Hockey League (AHL). Weber has represented Canada at a number of International Ice Hockey Federation (IIHF)-sanctioned events, winning a World Junior Ice Hockey Championship gold medal in 2005, an Ice Hockey World Championships gold medal in 2007, and two Olympic gold medals at the 2010 and 2014 Winter Olympics. Weber was traded to the Canadiens in exchange for P. K. Subban on June 29, 2016.

The 10.30 Slot was a music and variety show that aired on ABC TV on Friday nights between 1999 and 2000, which was hosted by Dylan Lewis and Angus Sampson. It was similar in format to Lewis and Sampson's previous show, Recovery, although The 10.30 Slot's late-night timeslot allowed for more adult-oriented content, compared to Recovery's youth-based focus. Ironically the program often did not start at 10:30pm as the title would suggest, but the time of its airing was contingent on the late edition of ABC News and other ABC broadcasting priorities on a particular Friday night.

Protocadherin beta-9 is a protein that in humans is encoded by the PCDHB9 gene. This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell a

Protocadherin beta-4 is a protein that in humans is encoded by the PCDHB4 gene. This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell a

Nina Boucicault (27 February 1867 – 2 August 1950) was an English actress born to playwright Dion Boucicault and his wife, actress Agnes Kelly Robertson. She had three brothers, Dion William (1855–1876), Dion Boucicault Jr. and Aubrey Boucicault, and two sisters, Eva and Patrice. Her debut was at the Louisville Opera House and as a child she performed with her father. Beginning in 1892, she played Kitty Verdun in the original production of the hit comedy Charley's Aunt. She was the first to play the title role in J. M. Barrie's Peter Pan, beginning in 1904 at the Duke of York's Theatre. She retired aged 60 in 1927, returning to the stage in 1935 and 1936 in Frolic Wind and Waste, respectively, and died at Hamilton Road, Ealing. She was married three times: firstly to G. D. Pitman; secondly to E. H. Kelly; and thirdly to Donald Innes-Smith.

Lithuanian nationality law operates on the jus sanguinus principle, whereby persons who have a claim to Lithuanian ancestry, either through parents, grandparents, great-grandparents may claim Lithuanian nationality.. Citizenship may also be granted by naturalization. Naturalization requires a residency period, an examination in the Lithuanian language, examination results demonstrating familiarity with the Lithuanian Constitution, a demonstrated means of support, and an oath of loyalty. A right of return clause was included in the 1991 constitution for persons who left Lithuania after its occupation by the Soviet Union in 1940 and their descendants. Lithuanian citizens are also citizens of the European Union and thus enjoy rights of free movement and have the right to vote in elections for

Protocadherin beta-4 is a protein that in humans is encoded by the PCDHB4 gene. This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Hexagonal chess refers to a group of chess variants played on boards composed of hexagon cells. The best known is Gliński's variant, played on a symmetric 91-cell hexagonal board. Since each hexagonal cell not on a board edge has six neighbor cells, there is increased mobility for pieces compared to a standard orthogonal chessboard. (E.g., a rook has six natural directions for movement instead of four.) Three colours are typically used so that no two neighboring cells are the same colour, and a colour-restricted game piece such as the orthodox chess bishop usually comes in sets of three per player in order to maintain the game's balance. Many different shapes and sizes of hexagon-based boards are used by variants. The nature of the game is also affected by the 30° orientation of the board's cells; the board can be horizontally (Wellisch's, de Vasa's, Brusky's) or vertically (Gliński's, Shafran's, McCooey's) oriented. (E.g., when the sides of hexagonal cells face the players, pawns typically have one straightforward move direction. If a variant's gameboard has cell vertices facing the players, pawns typically have two oblique-forward move directions.) The six-sidedness of the symmetric hexagon gameboard has also resulted in a number of three-player variants. The first applications of chess on hexagonal boards probably occurred mid-19th century, but two early examples did not include checkmate as the winning objective. More chess-like games for hexagon-based boards started appearing regularly at the beginning of the 20th century. Hexagon-celled gameboards have grown in use for strategy games generally; for example, they are popularly used in modern wargaming.

Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (PP2BC) is an enzyme that in humans is encoded by the PPP3CC gene. Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha (CALNA1; MIM 114105), calcineurin A-beta (CALNA2; MIM 114106), and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been iden

Solute carrier family 2, facilitated glucose transporter member 9 is a protein that in humans is encoded by the SLC2A9 gene. This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene.

Paper is a thin unwoven material made from milled plant fibers, is primarily used for writing, artwork, and packaging; it is commonly white. The first papermaking process was documented in China during the Eastern Han period (25–220 CE), traditionally attributed to the court official Cai Lun. Officially paper was invented by the Ancient Chinese. Papyrus is different and was invented by Egyptians. During the 8th century, Chinese papermaking spread to the Islamic world, where pulp mills and paper mills were used for papermaking and money making. By the 11th century, papermaking was brought to Europe. By the 13th century, papermaking was refined with paper mills utilizing waterwheels in Spain. Later European improvements to the papermaking process came in the 19th century with the invention of wood-based papers. Although precursors such as papyrus and amate existed in the Mediterranean world and pre-Columbian Americas, respectively, these materials are not defined as true paper. Nor is true parchment considered paper; used principally for writing, parchment is heavily prepared animal skin that predates paper and possibly papyrus. In the twentieth century with the advent of plastic manufacture some plastic "paper" was introduced, as well as paper-plastic laminates, paper-metal laminates, and papers infused or coated with different products that give them special properties.

The 2008 Tampa Bay Buccaneers season was the franchise's 33rd season in the National Football League the 11th playing their home games at Raymond James Stadium, and the seventh and final under head coach Jon Gruden. Though the team finished with a winning record (9–7), they failed to defend their 2007 NFC South championship and did not qualify for the playoffs for the first time since 2006, after finishing the year on a four-game losing streak. Just weeks after the conclusion of the regular season, head coach Jon Gruden was fired,a move that came as a surprise both to sports writers and Gruden himself. General manager Bruce Allen was also fired. The failure of the Buccaneers to return to the Super Bowl marked the 24th consecutive year in which the Super Bowl did not include the team in whose region the game was being played a feat that never has been achieved since the 49ers in 1984. The 2008 season marked a turning point in Tampa's history. From 2008 to present, the Tampa Bay Buccaneers have failed to make the playoffs.

Theodosius I (Latin: Flavius Theodosius Augustus; Greek: Θεοδόσιος Αʹ; 11 January 347 – 17 January 395), also known as Theodosius the Great, was a Roman Emperor from 379 to 395, and the last emperor to rule over both the Eastern and the Western halves of the Roman Empire. On accepting his elevation, he campaigned against Goths and other barbarians who had invaded the Empire. His resources were not sufficient to destroy them or drive them out, which had been Roman policy for centuries in dealing with invaders. By treaty, which followed his indecisive victory at the end of the Gothic War, they were established as foederati, autonomous allies of the Empire, south of the Danube, in Illyricum, within the Empire's borders. They were given lands and allowed to remain under their own leaders, a grave departure from Roman hegemonic ways. This turn away from traditional policies was accommodationist and had grave consequences for the Western Empire from the beginning of the century, as the Romans found themselves with the impossible task of defending the borders and deal with unruly federates within. Theodosius I was obliged to fight two destructive civil wars, successively defeating the usurpers Magnus Maximus in 387-388 and Eugenius in 394, though not without material cost to the power of the Empire. He issued decrees that effectively made Nicene Christianity the official state church of the Roman Empire. He neither prevented nor punished the destruction of prominent Hellenistic temples of classical antiquity, including the Temple of Apollo in Delphi and the Serapeum in Alexandria. He dissolved the Order of the Vestal Virgins in Rome. In 393, he banned the pagan rituals of the Olympics in Ancient Greece. After his death, Theodosius's young sons Arcadius and Honorius inherited the east and west halves of the empire respectively, and the Roman Empire was never again re-united, though Eastern Roman emperors after Zeno would claim the united title after Julius Nepos's death in 480. Theodosius is considered a saint by the Armenian Apostolic Church and Eastern Orthodox Church, and his feast day is on January 19.

Shea Michael Weber (born August 14, 1985) is a Canadian professional ice hockey defenceman who currently serves as the captain for the Montreal Canadiens of the National Hockey League (NHL). He is an NHL All-Star and a two-time Olympic gold medalist. Weber has represented Canada at a number of International Ice Hockey Federation (IIHF)-sanctioned events, winning a World Junior Ice Hockey Championship gold medal in 2005, an Ice Hockey World Championships gold medal in 2007, and two Olympic gold medals at the 2010 and 2014 Winter Olympics.

Félix Sesúmaga Ugarte (born 12 October 1898 – 24 August 1925) was a Spanish (Basque) footballer during the 1910s and the 1920s. Born in Lejona, Vizcaya, he played as a forward for Arenas Club de Getxo, FC Barcelona, Racing de Sama de Langreo, Athletic Bilbao and Spain. Sesúmaga won the Copa del Rey three times with three clubs and also played in two successive finals for two clubs. In 1920 Sesúmaga was also a member of the very first Selección that played at the Olympic Games in Belgium. He scored twice as Spain beat the Netherlands 3–1 in the play-off for the silver medal. He played 8 times for Spain, scoring 4 goals between 1920 and 1923. In the 1919 Copa del Rey final, Sesúmaga scored a hat-trick for Arenas Club de Getxo as they beat FC Barcelona 5–2. FC Barcelona were impressed enough to sign him and in the 1920 Copa final he helped his new club beat Athletic Bilbao 2–0. He was a member of the legendary FC Barcelona team, coached by Jack Greenwell, that also included Paulino Alcántara, Sagibarba, Ricardo Zamora and Josep Samitier. During his time at the club he also helped them win three Championat de Catalunya titles. After a season at Racing de Sama de Langreo, he joined Athletic Bilbao and won the Copa del Rey for a third time in 1923 when they beat CE Europa 1–0. He died from tuberculosis at the age of 26.

Dulcify (1975–1979) was a New Zealand-bred Thoroughbred racehorse. His British-bred sire was the 1970 Irish 2,000 Guineas winner, Decies, a grandson of Pharis, the very important French sire whom Thoroughbred Heritage says is considered one of the greatest French-bred runners of the century. Dulcify's dam was the Australian mare Sweet Candy, a daughter of 1957 Golden Slipper Stakes winner and Australian Racing Hall of Fame inducteeTodman. Dulcify was owned and raced by Colin Hayes, who purchased him for $3,250. Hayes called him the best horse he ever raced.

La Cenicienta (Cinderella) is an opera in three acts composed by Chilean artist Jorge Peña Hen (1928–1973), to a libretto by the Chilean author, (1910–1988). This opera is one of the few operas in the world composed with the aim to be sung, acted and played exclusively by children. It was written in 1966 and played by Jorge Peña Hen's first at the Theater of the Girls Public School in La Serena, a city in the northern region of Coquimbo. In 1986, a new version of this children's opera was played in Colombia. The plot of the opera is based on Charles Perrault's classic fairy tale Cinderella.

Protein phosphatase 1F is an enzyme that in humans is encoded by the PPM1F gene. The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined.

Acoustical Intelligence (ACOUSTINT, sometimes ACINT) is an intelligence gathering discipline that collects and processes acoustic phenomena. It is a subdiscipline of MASINT (Measurement and Signature Intelligence). This uses broadband and narrowband analysis of acquired acoustic signatures from surface ships and submarines, although it can also be used for low-flying aircraft such as helicopters. Broadband analysis concerns the overall noise created by a platform, whereas narrowband analysis examines the spectra of the received energy at a more precise level.

The Normans in Ireland, or Hiberno-Normans, were a group of Normans who invaded the various realms of Gaelic Ireland. They arrived from the Kingdom of England and Wales from the 12th century onwards and established themselves as a feudal aristocracy and merchant oligarchy in the Lordship of Ireland which existed throughout the High Middle Ages and Late Middle Ages. They can in many ways be seen as a branch of the Normans in England and Wales. Most of the Normans eventually became Gaelicised, especially in the West. For instance, in Gaelic Munster where Cork was the Norman capital, proven statistically by the dominance of French names and linguistics.

Matthew Brett Cardona (born May 14, 1985) is an American professional wrestler. He is currently signed to WWE, where he performs on the Raw brand under the ring name Zack Ryder where he is one half of the Raw Tag Team Champions with Curt Hawkins. After joining WWE, he has since become a one-time Intercontinental Champion, a one-time United States Champion and a one-time WWE Tag Team Champion. Cardona began working in the professional wrestling industry in 2004, mainly as a tag team with Curt Hawkins on the independent circuit and then eventually in WWE, where they won the WWE's tag team championship. After the team split in 2009, Cardona made appearances on ECW. After ECW ended, he was featured sparingly on WWE television. In 2011, he started publishing a YouTube web series called Z! True Long Island Story where he proclaimed himself WWE's "", though this championship was not sanctioned by WWE. This and his use of social networking websites helped him in establishing a fan following and a bigger television role with WWE as a result.

39S ribosomal protein L4, mitochondrial is a protein that in humans is encoded by the MRPL4 gene. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence anal

The 2009 Tampa Bay Buccaneers season was the franchise's 34th season in the National Football League the 12th playing their home games at Raymond James Stadium, and the first under head coach Raheem Morris. The Buccaneers looked to improve on their 9–7 record from their 2008 season and 3rd-place finish in the NFC South but failed to do so as they finished the season at 3–13, missing the playoffs for the second straight year. The Buccaneers played seven of their home games at Raymond James Stadium. One of their home games was played at Wembley Stadium, as part of the International Series, in which they lost to the New England Patriots 35–7. The Buccaneers unveiled a Ring of Honor to celebrate the 30th anniversary of the 1979 franchise. Lee Roy Selmon was the first inductee when the team wore throwback uniforms on November 8 in a game against Green Bay that they won 38–28.