yes

CLEC1A (gene)

The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.

In Natural Language Processing, CLAWS is a program that performs Part-of-speech tagging.

CLA bulding

CLAY v. UNITED STATES

CLDN19

CLA Smith

Cleco Corp.

Chloride channel CLIC-like 1 also known as CLCC1 is a human gene.The protein encoded by this gene is a chloride channel which is related in sequence to the S. cerevisiae MID-1 stretch-activated channel. CLCC1 is located in the membranes of intracellular compartments including endoplasmic reticulum and the Golgi apparatus. It is highly expressed in the testis and moderately in the spleen, liver, kidney, heart, brain, and lung.

CLCN2

CLEC5A

CLAS was a standards-based assessment based on Outcomes Based Education principles given in California in the early 1990s. It was based on concepts of new standards such as whole language and reform mathematics. Instead of multiple choice tests with one correct answer, it used open written responses that were graded according to rubrics.

CLCS

CKU6

CLCN5

CLECSF11, CLECSF7

CLC-1 may refer to one of the following:USS Northampton, a United States Navy command light cruiser which served from 1953 until 1970CLC-1 Radar, a ground-based mobile tracking radar used by the People's Liberation Army of China

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Two alternatively spliced transcript variants that encode different isoforms have been identified for this gene.

The CLC-3 is a low altitude, mobile air defense radar that uses phased array and pulse doppler technologies to detect low flying targets such as helicopters and UAVs.The manufacturer of the system is Nanjing Research Institute of Electronics Technology(NRIET)/Nanjing Institute No. 1

Claudin-16 is a protein that in humans is encoded by the CLDN16 gene. It belongs to the group of claudins.Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space.

CLEI code

CLC International

Claudin-8 is a protein that in humans is encoded by the CLDN8 gene. It belongs to the group of claudins.

CLDN19 (gene)

H(+)/Cl(-) exchange transporter 5 is a protein that in humans is encoded by the CLCN5 gene.This gene encodes a member of the ClC family of chloride ion channels and ion transporters. Mutations in this gene have been found in Dent's Disease and renal tubular disorders complicated by nephrolithiasis. Although a member of a family of chloride channels, the CLCN5 protein allows movement of protons in the opposite direction of Cl(-), thus functioning as an antiporter.

Chloride channel 7 alpha subunit also known as H+/Cl− exchange transporter 7 is a protein that in humans is encoded by the CLCN7 gene. In melanocytic cells this gene is regulated by the Microphthalmia-associated transcription factor.

CLC1

CLD is a vibrant blue dye originally synthesized for application in nonlinear electro-optics.

Chloride channel Kb, also known as CLCNKB, is a protein which in humans is encoded by the CLCNKB gene.Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter syndrome. CLCNKA and CLCNKB are closely related (94% sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.

CLA (O)

CLC-1 short-range surveillance radar is a ground-based mobile tracking radar used by the People's Liberation Army of China.

CLD

CLCN4 (gene)

CLDF

CLEO (particle detector)

Claudin-9 is a protein that in humans is encoded by the CLDN9 gene. It belongs to the group of claudins.This gene is involved in hearing.

CKUA

United States

CLDN4 (gene)

CLCN3 (gene)

C-type lectin domain family 11 member A is a protein that in humans is encoded by the CLEC11A gene.This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined.

C-type lectin domain family 7 member A or Dectin-1 is a protein that in humans is encoded by the CLEC7A gene. CLEC7A is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with a partial immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor for a variety of β-1,3-linked and β-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Expression is found on myeloid dendritic cells, monocytes, macrophages and B cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Claudin-20 is a protein that in humans is encoded by the CLDN20 gene. It belongs to the group of claudins.

C-type lectin domain family 1 member A is a protein that in humans is encoded by the CLEC1A gene.This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded protein may play a role in regulating dendritic cell function.

CLDN14 (gene)

CLC H-24-66

CLASS R-80 Bush Caddy

CKKN-FM-2

This gene encodes L-SIGN , a type II integral membrane protein that is 77% identical to CD209 antigen, an HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

International Council

CLEI

CLAS (education)

CLEO - Cisco router in Low Earth Orbit, is an Internet router from Cisco Systems that was integrated into the UK-DMC Disaster Monitoring Constellation satellite built by Surrey Satellite Technology Ltd (SSTL) as a secondary experimental hosted payload, and launched into space with the satellite from Plesetsk on 27 September 2003.CLEO and the UK-DMC satellite were tested over five years to show the feasibility of extending the Internet to orbit, using both the Internet Protocol and Mobile IP.

H+/Cl− exchange transporter 3 is a protein that in humans is encoded by the CLCN3 gene.

CLCNKB (gene)

CLASS L-62 Max

CLEO Cisco router in Low Earth Orbit

C-type lectin domain family 4 member M is a protein that in humans is encoded by the CLEC4M gene. CLEC4M has also been designated as CD299 (cluster of differentiation 299).This gene encodes L-SIGN (liver/lymph node-specific intracellular adhesion molecules-3 grabbing non-integrin), a type II integral membrane protein that is 77% identical to CD209 antigen, an HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

CLAЯITY

CLEC12A

CLEC2B (gene)

CLC International is an International Christian Literature mission committed to the distribution of the Bible, Christian books and a variety of Christian media. CLC is short for "Christian Literature Crusade". CLC works in 58 countries and has more than 800 workers worldwide. It is represented by more than 180 bookshops, 18 distribution warehouses and 18 publishing houses.

C-type lectin domain family 16, also known as CLEC16A, is a protein that in humans is encoded by the CLEC16A gene.

Public

CLEAR campaign

CLB 5

CLC Academy

CLCNKB

Claudin-1 is a protein that in humans is encoded by the CLDN1 gene. It belongs to the group of claudins.

C-type lectin domain family 4 member A is a protein that in humans is encoded by the CLEC4A gene.This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

CLDC

CLB-26

CLCA1

CLBI

Eosinophil lysophospholipase is an enzyme that in humans is encoded by the CLC gene.Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias.

CLE

C-type lectin domain family 12 member A is a protein that in humans is encoded by the CLEC12A gene.This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function.

CLEC4A (gene)

CLEO was a general purpose particle detector at the Cornell Electron Storage Ring (CESR), and the name of the collaboration of physicists who operated the detector. The name CLEO is not an acronym; it is short for Cleopatra and was chosen to go with CESR (pronounced Caesar). CESR was a particle accelerator designed to collide electrons and positrons at a center-of-mass energy of approximately 10 GeV. The energy of the accelerator was chosen before the first three bottom quark Upsilon resonances were discovered between 9.4 GeV and 10.4 GeV in 1977. The fourth Υ resonance, the Υ(4S), was slightly above the threshold for, and therefore ideal for the study of, B meson production.CLEO was a hermetic detector that in all of its versions consisted of a tracking system inside a solenoid magnet, a calorimeter, particle identification systems, and a muon detector. The detector underwent five major upgrades over the course of its thirty-year lifetime, both to upgrade the capabilities of the detector and to optimize it for the study of B mesons. The CLEO I detector began collecting data in October 1979, and CLEO-c finished collecting data on March 3, 2008.CLEO initially measured the properties of the Υ(1–3S) resonances below the threshold for producing B mesons. Increasing amounts of accelerator time were spent at the Υ(4S) as the collaboration became more interested in the study of B mesons. Once the CUSB experiment was discontinued in the late 1980s, CLEO then spent most of its time at the Υ(4S) and measured many important properties of the B mesons.While CLEO was studying the B mesons, it was also able to measure the properties of D mesons and tau leptons, and discover many new charm hadrons. When the BaBar and Belle B factories began to collect large amounts of data in the early 2000s, CLEO was no longer able to make competitive measurements of B mesons. CLEO revisited the Υ(1-3S) resonances, then underwent its last upgrade to CLEO-c. CESR ran at lower energies and CLEO measured many properties of the ψ resonances and D mesons. CLEO was the longest running experiment in the history of particle physics.

CLCI

Claudin-5 is a protein that in humans is encoded by the CLDN5 gene. It belongs to the group of claudins.

CLDN9

CLC4

C-type lectin domain family 9 member A is a protein that in humans is encoded by the CLEC9A gene.

Claudin-14 is a protein that in humans is encoded by the CLDN14 gene. It belongs to a related family of proteins called claudins.The protein encoded by CLDN14 is an integral membrane protein and a component of tight junctions, one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets.

CLEC9A

CLB

The CLAW hypothesis proposes a negative feedback loop that operates between ocean ecosystems and the Earth's climate. The hypothesis specifically proposes that particular phytoplankton that produce dimethyl sulfide are responsive to variations in climate forcing, and that these responses act to stabilise the temperature of the Earth's atmosphere. The CLAW hypothesis was originally proposed by Robert Jay Charlson, James Lovelock, Meinrat Andreae and Stephen G.

H(+)/Cl(-) exchange transporter 4 is a protein that in humans is encoded by the CLCN4 gene.

CLEFIA is a proprietary block cipher algorithm, developed by Sony. Its name is derived from the French word clef, meaning "key". The block size is 128 bits and the key size can be 128 bit, 192 bit or 256 bit. It is intended to be used in DRM systems. It is among the cryptographic techniques recommended candidate for Japanese government use by CRYPTREC revision in 2013.

CLDN18

CLEC4M (gene)

CLEC2D

Chloride channel accessory 4, also known as CLCA4, is a protein which in humans CLCA4 gene. The protein encoded by this gene is a chloride channel. Protein structure prediction methods suggest the N-terminal region of CLCA4 protein is a zinc metalloprotease, and the protein is not an ion channel per se.

Claudin-2 is a protein that in humans is encoded by the CLDN2 gene. It belongs to the group of claudins.Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions (Sakaguchi et al., 2002).[supplied by OMIM]

CLDND1 (gene)

C-type lectin domain family 7 member A or Dectin-1 is a protein that in humans is encoded by the CLEC7A gene. CLEC7A is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with a partial immunoreceptor tyrosine-based activation motif.

CLDN11

The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer. Protein structure prediction methods suggest the N-terminal region of CLCA2 protein is a zinc metalloprotease.

Chloride transport protein 6 is a protein that in humans is encoded by the CLCN6 gene.The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 6 and 7 belong to a subbranch of this family. Chloride channel 6 has four different alternatively spliced transcript variants. This gene is in close vicinity to two other kidney-specific chloride channel genes, CLCNKA and CLCNKB.

Sony

CLC Bio

CLECO

Best songs, best variety!
CJPG-FM is a canadian radio station being licensed to Portage la Prairie, Manitoba, serving the Central Plains region of Manitoba broadcasting at 96.5 FM with a hot adult contemporary format branded as "Mix 96.5". The station is currently owned by Golden West Broadcasting, and is located at 2390 Sissons Drive, along with sister stations CFRY and CHPO-FM.

CLC 1

C-type lectin domain family 2 member B is a protein that in humans is encoded by the CLEC2B gene.This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen. An alternative splice variant has been described but its full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Claudin-19 is a protein that in humans is encoded by the CLDN19 gene. It belongs to the group of claudins. Claudin-19 has been implicated in magnesium transport.Claudins, such as CLDN19, are transmembrane proteins found at tight junctions. Tight junctions form barriers that control the passage of ions and molecules across an epithelial sheet and the movement of proteins and lipids between apical and basolateral domains of epithelial cells (Lee et al., 2006).[supplied by OMIM]

Claudin-6 is a protein that in humans is encoded by the CLDN6 gene. It belongs to the group of claudins.

CLB6

Sheffield, United Kingdom

CLDR

CLB-8

CLDN15

Claudin-10 is a protein that in humans is encoded by the CLDN10 gene. It belongs to the group of claudins.This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Two alternatively spliced transcript variants that encode different isoforms have been identified for this gene.

CLC CPA-16-4

Christian literature distribution

Claudin-12 is a protein that in humans is encoded by the CLDN12 gene. It belongs to the group of claudins.

CLEC7A (gene)

CLEAN Algorithm

CLEC3B

CK&N

CLC bio

CLC CFB-16-5

CLDN16

CLCN5 (gene)

CLB 15

CLEC5A (gene)

CLDN20

C J PortaGe la Prairie

CLEC2

CLCA1 (gene)

CLEC11A (gene)

CLEC7A

C-type lectin domain family 4, member C

Claudin 3, also known as CLDN3, is a protein which in humans is encoded by the CLDN3 gene. It is a member of the claudin protein family.Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space.

CLAS consultant

CLEC16A (gene)

CLDN22 (gene)

CLEFIA

CLC Protocol

Claudin-18 is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins.CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells . [supplied by OMIM]

CLEO

CLAW

CLCN6

The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane.

Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions .[supplied by OMIM]

Chloride channel protein 2 is a protein that in humans is encoded by the CLCN2 gene. Mutations of this gene have been found to cause leukoencephalopathy (PMID 23707145) and Idiopathic generalised epilepsy (OMIM: 600699). CLCN2 contains a transmembrane region that is involved in chloride ion transport as well two intracellular copies of the CBS domain.

CLED agar

CLCN7 (gene)

CLDN1 (gene)

CLB-15

C-type lectin domain family 12 member A is a protein that in humans is encoded by the CLEC12A gene.This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.

CLEC4C

CLEO Bachelor of the Year

C-type lectin domain family 5 member A or CLEC5A, also known as C-type lectin superfamily member 5 (CLECSF5) and myeloid DAP12-associating lectin 1 (MDL1) is a C-type lectin that in humans is encoded by the CLEC5A gene. It appears to be a member of a significant myeloid lineage activating pathway.

To make evangelical literature available to all nations

CLEAR (DOS)

CLCNKA (gene)

CLC3

CLAW hypothesis

CLC CPA-16-5

CLAWS

CLD (disambiguation)

CLCIMS

CLC Publications

CLEO (router)

Electricity

CLDN16 (gene)

CLEC4C is a membrane protein of plasmacytoid dendritic cells used as a marker for this kind of cells and denoted as CD303 in the nomenclature of the Cluster of differentiation.

CLD3

CLDN17

This gene encodes a member of the ClC family of chloride ion channels and ion transporters. Mutations in this gene have been found in Dent's Disease and renal tubular disorders complicated by nephrolithiasis. Although a member of a family of chloride channels, the CLCN5 protein allows movement of protons in the opposite direction of Cl, thus functioning as an antiporter.

CLC bio is a bioinformatics software company headquartered in Aarhus, Denmark, and with offices in Cambridge, Massachusetts, Tokyo, Taipei and Delhi. CLC bio's software has more than 250,000 users in more than 100 countries around the globe.

Tetranectin is a protein that in humans is encoded by the CLEC3B gene.

Claudins, such as CLDN7, are involved in the formation of tight junctions between epithelial cells. Tight junctions restrict lateral diffusion of lipids and membrane proteins, and thereby physically define the border between the apical and basolateral compartments of epithelial cells .[supplied by OMIM]

CLEC4M

CLEAN Energy Act

This gene encodes a member of the C-type lectin/C-type lectin-like domain superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.

Mix 96.5 FM

CLDN8 (gene)

CLDN9 (gene)

Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. It belongs to the group of claudins.Claudins, such as CLDN7, are involved in the formation of tight junctions between epithelial cells. Tight junctions restrict lateral diffusion of lipids and membrane proteins, and thereby physically define the border between the apical and basolateral compartments of epithelial cells (Zheng et al., 2003).[supplied by OMIM]

CLEAN (disambiguation)

CLE4

CLCN3

Chloride channel protein ClC-Ka is a protein that in humans is encoded by the CLCNKA gene. Multiple transcript variants encoding different isoforms have been found for this gene.

CLEC (disambiguation)

CLD chromophore

CLEC11A

CLEC2D (gene)

Chloride channel accessory 3, also known as CLCA3, is a protein which in humans is encoded by the CLCA3P pseudogene. The protein encoded by this gene is a chloride channel. This protein is not expressed in humans but is in certain other species such as mouse.

Claudins, such as CLDN19, are transmembrane proteins found at tight junctions. Tight junctions form barriers that control the passage of ions and molecules across an epithelial sheet and the movement of proteins and lipids between apical and basolateral domains of epithelial cells .[supplied by OMIM]

CLC (South Korean band)

CLAS was a standards-based assessment based on Outcomes Based Education principles given in California in the early 1990s. It was based on concepts of new standards such as whole language and reform mathematics. Instead of multiple choice tests with one correct answer, it used open written responses that were graded according to rubrics. Such tests were thought to be fairer to students of all abilities.Failure rates among all groups, particularly minorities, was so high that it generated concern. It was terminated in 1995 by the governor after two years.Maureen DiMarco testified to the California State Legislature in charge of the [CLAS] that no graders were allowed to give a "4" top score in mathematics in the first year. It was based on open responses scored holistically, so that the correct answer to how to share 5 apples among 4 people might be to give the 5th to a food bank.Minorities scored even lower than on standardized tests, huge numbers scored in the lowest categories, as open response questions with more than one answer proved to be even more difficult than multiple choice problems.It was replaced by STAR, which is a testing system based on traditional rigorous academic standards which largely discards the theory of outcome-based education which was widely rejected by the late 1990s in the United States.

CLB-5

Software and consulting

CLEI codes

CLEAR

Chloride transport protein 6 is a protein that in humans is encoded by the CLCN6 gene.The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 6 and 7 belong to a subbranch of this family. Chloride channel 6 has four different alternatively spliced transcript variants.

CLDN18 (gene)

C-type lectin domain family 2 member D is a protein that in humans is encoded by the CLEC2D gene.This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified, but the full-length nature of every transcript has not been defined.

CLB-13

CLAT (disambiguation)

CJPG-FM

CLDN6

CLDN10

Q8WTT0

CLB (disambiguation)

CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells . [supplied by OMIM]

CLCI MSG

CLDN2

CLB-31

CLDN3

CLDN8

C-type lectin domain family 10 member A also known as CLEC10A is a protein that in humans is encoded by the CLEC10A gene.

CLEC1A

Claudin-16 is a protein that in humans is encoded by the CLDN16 gene. It belongs to the group of claudins.Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are composed of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure.

The protein encoded by CLDN14 is an integral membrane protein and a component of tight junctions, one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets. Tight junctions form continuous seals around cells and serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space.

These junctions are composed of sets of continuous networking protein strands in the outer surface of the cell membrane, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The CLDN14 protein also binds to particular part of a protein called Yes-associated protein, known as its WW domain.

Defects in CLDN14 are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. Two transcript variants encoding the same protein have been found for this gene.

CLDN6 (gene)

This gene encodes a member of the C-type lectin/C-type lectin-like domain superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

CLDN7

CLCN6 (gene)

Chloride channel accessory 2 is a protein that in humans is encoded by the CLCA2 gene.The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions.

CLDN11 (gene)

CLEAN

CLCL

CLAS detector

The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen).Chloride channel protein, skeletal muscle (CLCN1) is a protein that in humans is encoded by the CLCN1 gene. Mutations in this protein cause congenital myotonia.CLCN1 is critical for the normal function of skeletal muscle cells. For the body to move normally, skeletal muscles must tense (contract) and relax in a coordinated way. Muscle contraction and relaxation are controlled by the flow of ions into and out of muscle cells. CLCN1 forms an ion channel that controls the flow of negatively charged chloride ions into these cells. The main function of this channel is to stabilize the cells' electrical charge, enabling muscles to contract normally.In people with congenital myotonia due to a mutation in CLCN1, the ion channel admits too few chloride ions into the cell. This shortage of chloride ions causes prolonged muscle contractions, which are the hallmark of myotonia.

CLB2

CLDN5 (gene)

CLC Class

The CLCN family of voltage-dependent chloride channel genes comprises nine members which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita and dominant myotonia .

CEBAF Large Acceptance Spectrometer (CLAS) is a nuclear and particle physics detector located in the experimental Hall B at Jefferson Laboratory in Newport News, Virginia, United States.

CLEC3B (gene)

CLC-36

Cardiotrophin-like cytokine factor 1 (CLCF1), also known as Novel Neurotrophin-1 (NNT-1) or B cell-stimulating factor-3 (BSF-3), is a protein that in humans is encoded by the CLCF1 gene.

CLDN22

CLDN17 (gene)

International Director

CLA (LO)

CLAY BUCHOLZ

CEBAF Large Acceptance Spectrometer (CLAS) is a nuclear and particle physics detector located in the experimental Hall B at Jefferson Laboratory in Newport News, Virginia, United States. It is used to study the properties of the nuclear matter by the collaboration of over 200 physicist (CLAS Collaboration) from many countries all around the world.The 0.5 to 12.0 GeV electron beam from the accelerator of Jefferson Laboratory is brought into "Hall B", the experimental hall that houses the CLAS system. Electrons or photons in the incoming beam collide with the nuclei of atoms in the physics "target" located at the center of CLAS. These collisions generally produce new particles, often after the target nucleons (protons and neutrons) are briefly excited to heavier-mass versions of the familiar protons and neutrons. A whole variety of intermediate-mass short-lived particles called "mesons" can be created. Scattered electron as well as the longer-lived produced particles travel through the CLAS detector, where they are measured. Particle physicists use these measurements to deduce the underlying structure of protons and neutrons and to better understand the interactions that create these new particles.The CLAS detector system was operational from 1998 until May 2012. From that time onward, analysis of archived data continued for some years, as can be traced in the publications. Since 2012, a similar but new system called CLAS12 was constructed, which is scheduled to start operations with particle beams in 2017.

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are composed of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure.

CLA (disambiguation)

CLEO - Cisco router in Low Earth Orbit, is an Internet router from Cisco Systems that was integrated into the UK-DMC Disaster Monitoring Constellation satellite built by Surrey Satellite Technology Ltd (SSTL) as a secondary experimental hosted payload, and launched into space with the satellite from Plesetsk on 27 September 2003.CLEO and the UK-DMC satellite were tested over five years to show the feasibility of extending the Internet to orbit, using both the Internet Protocol and Mobile IP. CLEO was configured by NASA's Glenn Research Center to be used with Virtual Mission Operations Center (VMOC) software from General Dynamics as part of a large internetworking exercise from the field at Vandenberg Air Force Base in June 2004.On 29 March 2007, CLEO was configured for and tested on IPsec and IPv6 use, making this the first use of IPv6 on board a satellite in orbit.The use of CLEO builds on and validates the approach to use of the Internet Protocol articulated by Keith Hogie with NASA Goddard and first demonstrated as part of the Operating Missions as Nodes on the Internet (OMNI) effort on board the UoSAT-12 satellite built by SSTL.CLEO was followed by the IRIS router on a geostationary Intelsat satellite.

CLEMI

CLEA

CLEC4E

CLCN1 (gene)

CLDN2 (gene)

worldwide

CLEAR’S

CKU7

CLB-24

CLASS R-80 BushCaddy

Chloride channel accessory 2 is a protein that in humans is encoded by the CLCA2 gene.The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer. Protein structure prediction methods suggest the N-terminal region of CLCA2 protein is a zinc metalloprotease.

CLC-Class

CLC-16

CLBV

CLB-22

CLC (gene)

C-type lectin domain family 4 member M is a protein that in humans is encoded by the CLEC4M gene. CLEC4M has also been designated as CD299 (cluster of differentiation 299).This gene encodes L-SIGN (liver/lymph node-specific intracellular adhesion molecules-3 grabbing non-integrin), a type II integral membrane protein that is 77% identical to CD209 antigen, an HIV gp120-binding protein.

CLEET

Claudin domain-containing protein 1 is a protein that in humans is encoded by the CLDND1 gene.

Claudin-15 is a protein that in humans is encoded by the CLDN15 gene. It belongs to the group of claudins.

CLC CFB-16-4

English

CLB 1

The CLCN family of voltage-dependent chloride channel genes comprises nine members which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 6 and 7 belong to a subbranch of this family. Chloride channel 6 has four different alternatively spliced transcript variants. This gene is in close vicinity to two other kidney-specific chloride channel genes, CLCNKA and CLCNKB.

CLCI S/S

This gene encodes a member of the C-type lectin/C-type lectin-like domain superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded protein may play a role in regulating dendritic cell function. Alternative splice variants have been described but their biological nature has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

CLB-3

CK&S

Chloride channel Kb, also known as CLCNKB, is a protein which in humans is encoded by the CLCNKB gene.Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter syndrome.

CLDN4

CLCF1

Cleco (formerly the Central Louisiana Electric Company) is an energy services company founded in January 1935 in Pineville in Rapides Parish in Central Louisiana. It operates a regulated electric utility company, Cleco Power, that serves approximately 281,000 customers across Louisiana. Cleco also operates an unregulated wholesale energy business, Cleco Midstream, with approximately 775 megawatts of generating capacity.

C-type lectin domain family 2 member B is a protein that in humans is encoded by the CLEC2B gene.This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen.

CLEM7

CLB-2

CLEC-2

CLCA3

CLB-6

CLA Young Adult Book Award

CLB 7

CLCA4 (gene)

CLCC1 (gene)

CLEMENTINE MAERSK

Claudin 4, also known as CLDN4, is a protein which in humans is encoded by the CLDN4 gene. It belongs to the group of claudins.This gene encodes an integral membrane protein, which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

CLC-1

CLEO was a general purpose particle detector at the Cornell Electron Storage Ring (CESR), and the name of the collaboration of physicists who operated the detector. The name CLEO is not an acronym; it is short for Cleopatra and was chosen to go with CESR (pronounced Caesar). CESR was a particle accelerator designed to collide electrons and positrons at a center-of-mass energy of approximately 10 GeV.

CLDND1

C-type lectin domain family 1 member B is a protein that in humans is encoded by the CLEC1B gene.Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells.[supplied by OMIM]

CLB-11

Claudin-17 is a protein that in humans is encoded by the CLDN17 gene. It belongs to the group of claudins. It forms anion-selective paracellular channels and is localized mainly in kidney proximal tubules.

CLC-3 Radar

CLEAR (DOS command)

CLEAN Energy Act of 2007

CLAWS (linguistics)

Claudin-22 is a protein that in humans is encoded by the CLDN22 gene. It belongs to the group of claudins.

CLC CPA16-5

CLDN15 (gene)

Claudin-11 is a protein that in humans is encoded by the CLDN11 gene. It belongs to the group of claudins.The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.

"Energy Smart"

CLDN3 (gene)

Chloride channel accessory 1 is a protein that in humans is encoded by the CLCA1 gene.This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. Protein structure prediction methods suggest the N-terminal region of CLCA1 protein is a zinc metalloprotease.

CLCN2 (gene)

CLDN12

CLEC10A (gene)

CLDN20 (gene)

C-type lectin domain family 4 member A is a protein that in humans is encoded by the CLEC4A gene.This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response.

CLEP

CLAT

CLC-1 Radar

CLC-11

over 800

CLEC1B

CLDN10 (gene)

CLC Convention

The CLAW hypothesis proposes a negative feedback loop that operates between ocean ecosystems and the Earth's climate. The hypothesis specifically proposes that particular phytoplankton that produce dimethyl sulfide are responsive to variations in climate forcing, and that these responses act to stabilise the temperature of the Earth's atmosphere. The CLAW hypothesis was originally proposed by Robert Jay Charlson, James Lovelock, Meinrat Andreae and Stephen G. Warren, and takes its acronym from the first letter of their surnames.

CLCN1

An improbable differential attack requiring 2126.83 chosen plaintexts breaks 13 rounds with a complexity of 2126.83 encryptions for the key size of length 128 bits . Similar attacks apply for 14 and 15 rounds of CLEFIA for the key sizes 192 and 256 bits, respectively.

CLC-23

CLCA3P (gene)

CLEF

CLCA2

Chloride channel accessory 1 is a protein that in humans is encoded by the CLCA1 gene.This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions.

CLB-1

Eosinophil lysophospholipase is an enzyme that in humans is encoded by the CLC gene.Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities.

CLCFFFB

CLCF1 (gene)

CLCD

CLDN7 (gene)

CLCA4

CLCNKA

CLB-4

CLCA

CLASS R-120 BushCaddy

CLDN12 (gene)

Claudin 3, also known as CLDN3, is a protein which in humans is encoded by the CLDN3 gene. It is a member of the claudin protein family.Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are composed of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intron-less gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares amino acid sequence similarity with a putative apoptosis-related protein found in rat.

CLEC

CLEC2B

Claudin-14 is a protein that in humans is encoded by the CLDN14 gene. It belongs to a related family of proteins called claudins.The protein encoded by CLDN14 is an integral membrane protein and a component of tight junctions, one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets. Tight junctions form continuous seals around cells and serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space.These junctions are composed of sets of continuous networking protein strands in the outer surface of the cell membrane, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The CLDN14 protein also binds to particular part of a protein called Yes-associated protein, known as its WW domain.Defects in CLDN14 are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. Two transcript variants encoding the same protein have been found for this gene.There are also suggestions that CLDN14 plays a role in tumour angiogenesis (blood vessel formation), as deletion of a single copy of this gene leads to tight junction defects and leaky blood vessels in a mouse model.

This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined.

Neil Wardrope

CLB-46

CLC H-12-46

CLEC12A (gene)

CLEC4A

CLB-7

CLEC1B (gene)

CLC-21

CLAUDE W. SOMERS

CLDN1

CLEAR (disambiguation)

CLEAN LIVING MOVEMENTS

This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified, but the full-length nature of every transcript has not been defined. CLEC2D encodes the gene for the Lectin Like Transcript-1 protein which is a functional ligand for the human NKR-P1A receptor, encoded by the KLRB1 gene.
In mice, there are many orthologs of the CLEC2D gene, and the presumed homolog is Clr-b/Ocil . Clr-b has been implicated in missing-self recognition by natural killer cells through engagement of the NKR-P1B receptor.

CLA (Country Land and Business Association)

CLCA2 (gene)

Natural killer cells express multiple calcium-dependent lectin-like receptors, such as CD94 and NKG2D , that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells.[supplied by OMIM]

CLDN14

CLEC16A

CLEC10A

Claudin-10 is a protein that in humans is encoded by the CLDN10 gene. It belongs to the group of claudins.This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets.

CLAS (disambiguation)

This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. Protein structure prediction methods suggest the N-terminal region of CLCA1 protein is a zinc metalloprotease.

C-type lectin domain family 1 member A is a protein that in humans is encoded by the CLEC1A gene.This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded protein may play a role in regulating dendritic cell function. Alternative splice variants have been described but their biological nature has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

CLC2

CLC CPA16-4

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias.

CLC (disambiguation)

C-type lectin domain family 2 member D is a protein that in humans is encoded by the CLEC2D gene.This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified, but the full-length nature of every transcript has not been defined. CLEC2D encodes the gene for the Lectin Like Transcript-1 (LLT1) protein which is a functional ligand for the human NKR-P1A receptor, encoded by the KLRB1 gene. In mice, there are many orthologs of the CLEC2D gene, and the presumed homolog is Clr-b/Ocil (Clec2d). Clr-b has been implicated in missing-self recognition by natural killer cells through engagement of the NKR-P1B receptor.

CLEAR (command)

CLCN7

CLEPUL

CLBA

Claudin-11 is a protein that in humans is encoded by the CLDN11 gene. It belongs to the group of claudins.The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function.

CLCC1

CLCN4

CLDN5

CLA Book of the Year for Children Award

CLBO

This gene encodes a member of the C-type lectin/C-type lectin-like domain superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen. An alternative splice variant has been described but its full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.